Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jules L. Griffin"'
Autor:
Ross A. Breckenridge, Izabela Piotrowska, Keat-Eng Ng, Timothy J. Ragan, James A. West, Surendra Kotecha, Norma Towers, Michael Bennett, Petra C. Kienesberger, Ryszard T. Smolenski, Hillary K. Siddall, John L. Offer, Mihaela M. Mocanu, Derek M. Yelon, Jason R. B. Dyck, Jules L. Griffin, Andrey Y. Abramov, Alex P. Gould, Timothy J. Mohun
Publikováno v:
PLoS Biology, Vol 11, Iss 12 (2013)
Externí odkaz:
https://doaj.org/article/6a8fd36805ff492ba96d5efe8f050325
Publikováno v:
Metabolomics
Introduction Inductively coupled plasma mass spectrometry (ICP-MS) experiments generate complex multi-dimensional data sets that require specialist data analysis tools. Objective Here we describe tools to facilitate analysis of the ionome composed of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33fcc63f5e0d826505debde213918cb
https://www.repository.cam.ac.uk/handle/1810/329853
https://www.repository.cam.ac.uk/handle/1810/329853
Autor:
David C. Rubinsztein, Jules L. Griffin, Benjamin R. Underwood, Zeyn W. Green-Thompson, Peter J. Pugh, Roger A. Barker, P Simon Jones, Stanley E. Lazic, Sarah L Mason, James B. Rowe
Publikováno v:
Journal of Neurology
Preclinical data have shown that rilmenidine can regulate autophagy in models of Huntington’s disease (HD), providing a potential route to alter the disease course in patients. Consequently, a 2-year open-label study examining the tolerability and
Autor:
Andrew N. J. McKenzie, Lira Mamanova, Jhuma Pramanik, Steven Woodhouse, Anna V. Protasio, Xi Chen, Eviatar Natan, Zhichao Miao, Jennifer A. Walker, Jules L. Griffin, Jillian L. Barlow, Johan Henriksson, Gordon Dougan, Gozde Kar, Liora Haim-Vilmovsky, Jasmin Fisher, Matthew Berriman, Evelina Charidemou, Mirjana Efremova, John C. Marioni, Simon Clare, Proserpio, Sarah A. Teichmann
The transcription factorRorahas been shown to be important for the development of ILC2 and the regulation of ILC3, macrophages and Treg cells. Here we investigate the role ofRoraacross CD4+ T cells, bothin vitroas well as in the context of severalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793f3ebbb4cabcabd4ab16017be92585
Autor:
Laura B. L. Wittemans, Nita G. Forouhi, E.D.L. Rolfe, F. Imamura, Jake P. Mann, Claudia Langenberg, Nicholas J. Wareham, L.A. Lotta, Michael Allison, Albert Koulman, Jules L. Griffin
Publikováno v:
Journal of Hepatology. 68:S331-S332
Autor:
Jules L. Griffin, Tim Raine, Arthur Kaser, Ghazaleh Assadi, Katharina Boroviak, Mauro D'Amato, Markus Tschurtschenthaler, Svetlana Saveljeva, Nicole C. Kaneider, Karen Brown, Subhankar Mukhopadhyay, Simon Clare, Jonathan W. Ashcroft, Qifeng Zhang, Michael J.O. Wakelam, Gavin W. Sewell, Allan Bradley, Sarah L. Kempster, R. Andres Floto, Brendan Doe, M. Zaeem Cader, Gordon Dougan, Edwin R. Chilvers
Single-nucleotide variations in C13orf31 (LACC1) that encode p.C284R and p.I254V in a protein of unknown function (called 'FAMIN' here) are associated with increased risk for systemic juvenile idiopathic arthritis, leprosy and Crohn's disease. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2063f231f1f8a409d227212555ea2df0
Autor:
Lucy, Yang, Joseph, Cheriyan, David D, Gutterman, Ruth J, Mayer, Zsuzsanna, Ament, Jules L, Griffin, Aili L, Lazaar, David E, Newby, Ruth, Tal-Singer, Ian B, Wilkinson
Publikováno v:
Chest
Background Smoking and COPD are risk factors for cardiovascular disease, and the pathogenesis may involve endothelial dysfunction. We tested the hypothesis that endothelium-derived epoxyeicosatrienoic acid (EET)-mediated endothelial function is impai
Autor:
Rita Romano Adao, Ana Filipa Domingues, Cecilia Castro, Antonio Curti, Jules L. Griffin, Cristina Pina, Alice V Taylor
Publikováno v:
Blood. 132:2605-2605
Epigenetic dysregulation is at the heart of Acute Myeloid Leukemia (AML), and its mechanistic understanding holds promise in improving AML dismal prognosis. Modification of chromatin accessibility through post-translational modification of histones a
Autor:
Wang Min, Eleanor M. Bolton, Edward Chung Yern Wang, Jordan S. Pober, Rafia S. Al-Lamki, John Bradley, Jules L. Griffin, Paul Moore, Jun Wang, Aviva M. Tolkovsky, Sathia Thiru, J. Andrew Bradley
Publikováno v:
Journal of the American Society of Nephrology. 19:953-960
Death receptor 3 (DR3), a member of the TNF receptor (TNFR) superfamily, is induced in human renal tubular epithelial cells (TEC) in response to injury. This study examined the expression and actions of TL1A, the principal ligand for DR3. In histolog
Autor:
Matthew Harvey, X. Li, S. Wassell, Evelina Charidemou, Ben D. McNally, Jules L. Griffin, Tom Ashmore, Elise R. Orford, Michelle C. Venables
Publikováno v:
Clinical Nutrition. 36:S176