Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Jules Freund"'
Publikováno v:
The Journal of Experimental Medicine
1. Rabbits infected with bovine tubercle bacilli develop hyper-sensitiveness to an intracutaneous injection of tuberculin. This sensitiveness appears from the 2nd to the 6th week after infection and increases rapidly thereafter. Tests, as a rule, sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c806347af8fd27dcd10d12e26a3fe101
https://pubmed.ncbi.nlm.nih.gov/19870554
https://pubmed.ncbi.nlm.nih.gov/19870554
Autor:
Jules Freund
Publikováno v:
The Journal of Experimental Medicine
1. When toxic filtrates from cultures of B coli, B. typhosus, or meningococci are injected into the blood stream, peritoneal cavity, or subcutaneous tissue of tuberculous guinea pigs, the skin at the site of a tuberculin reaction becomes hemorrhagic.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e8717a43ff5a46833a101f504ce76b
https://pubmed.ncbi.nlm.nih.gov/19870331
https://pubmed.ncbi.nlm.nih.gov/19870331
Autor:
Jules Freund
Publikováno v:
The Journal of Experimental Medicine
1. Young and adult rabbits react differently to intracutaneous injection of virulent pneumococci. In adult rabbits a very extensive inflammation develops at the site of infection and bacteriemia and death occur only in a relatively few rabbits. Young
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10910a734b78e35a0b7370a3397bb354
https://doi.org/10.1084/jem.54.2.171
https://doi.org/10.1084/jem.54.2.171
Autor:
Jules Freund, D. Murray Angevine
Publikováno v:
The Journal of Immunology. 35:271-288
Willis (1) studied the passage of tubercle bacilli from the skin to the regional lymph nodes of normal and previously infected guinea pigs and found that their spread was greatly retarded in the reinfected animals. He demonstrated the presence or abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::731fa09370ed2586dd789a81908076e6
https://doi.org/10.4049/jimmunol.35.4.271
https://doi.org/10.4049/jimmunol.35.4.271
Autor:
Jules Freund, Eugene L. Opie
Publikováno v:
The Journal of Experimental Medicine
Heat killed tubercle bacilli repeatedly injected into or below the skin of rabbits increase conspicuously their resistance against infection with virulent tubercle bacilli. Protection against tuberculous infection following the administration of heat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c9e3fe2b00211e64dc5ad20019c95a
https://doi.org/10.1084/jem.66.6.761
https://doi.org/10.1084/jem.66.6.761
Publikováno v:
The Journal of Immunology. 71:380-384
Summary Pregnant guinea pigs were given a subcutaneous injection of CNS tissue in water-in-oil emulsion containing killed mycobacteria. Their offspring delivered at the time of the onset of encephalomyelitis in the mothers had no lesions in the CNS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bae8f94a3d641ea463c5fa0d995fdc0a
https://doi.org/10.4049/jimmunol.71.5.380
https://doi.org/10.4049/jimmunol.71.5.380
Autor:
Jules Freund, Mary V. Bonanto
Publikováno v:
The Journal of Immunology. 45:71-78
Summary Groups of rabbits were immunized by two courses of intravenous injections of alum precipitated diphtheric toxoid; the two courses were one or more months apart. One injection after the rest period gave far greater antibody response than could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49194fc23fdda08b3824139f0c605b3c
https://doi.org/10.4049/jimmunol.45.1.71
https://doi.org/10.4049/jimmunol.45.1.71
Autor:
Jules Freund
Publikováno v:
The Journal of Immunology. 21:127-137
As long as the chemical constitution of antibodies is not established and as long as antibodies are not available in pure state it seems desirable to study the action of substances that have a similar effect upon antigens. Probably of all the antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8af85dc8411d52d2df727ec1d6f2a127
https://doi.org/10.4049/jimmunol.21.2.127
https://doi.org/10.4049/jimmunol.21.2.127
Publikováno v:
The Journal of Immunology. 77:453-461
Summary and Conclusions Lethal anaphylactic shock has been elicited in rats sensitized with bovine serum albumin combined with adjuvants. Of 10 rats sensitized with bovine serum albumin combined with paraffin oil adjuvants containing mycobacteria, 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e33d973f3e86cf2c0274ad0f75b9cfcf
https://doi.org/10.4049/jimmunol.77.6.453
https://doi.org/10.4049/jimmunol.77.6.453
Publikováno v:
The Journal of Immunology. 60:383-398
Summary and Conclusions Antibody formation was enhanced and sustained when the antigen (typhoid bacillus) was incorporated into a water-in-oil emulsion prepared with paraffin oil and Falba or anhydrous lanolin or Arlacel A (mannide monooleate) or myr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0c126100182576e689051d59f10e165
https://doi.org/10.4049/jimmunol.60.3.383
https://doi.org/10.4049/jimmunol.60.3.383