Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jules, Deforges"'
Autor:
Laetitia Fend, Eric Quemeneur, Jean-Baptiste Marchand, Nathalie Silvestre, Johann Foloppe, Christelle Remy, Patricia Kleinpeter, Jules Deforges, Fadi Azar, Christelle Demeusoit, Clémentine Spring-Giusti
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background TG6050 was designed as an improved oncolytic vector, combining the intrinsic properties of vaccinia virus to selectively replicate in tumors with the tumor-restricted expression of recombinant immune effectors to modify the tumor immune ph
Externí odkaz:
https://doaj.org/article/51ec8ad7965d4c9fa9fa907be1c0686c
Autor:
Hélène Lê, Jules Deforges, Pasquale Cutolo, Anissa Lamarque, Guoqiang Hua, Véronique Lindner, Shreyansh Jain, Jean-Marc Balloul, Nadia Benkirane-Jessel, Eric Quéméneur
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Onco-virotherapy is an emergent treatment for cancer based on viral vectors. The therapeutic activity is based on two different mechanisms including tumor-specific oncolysis and immunostimulatory properties. In this study, we evaluated onco-virothera
Externí odkaz:
https://doaj.org/article/6c17b8192e2d4ef1ad592594a56141d4
Autor:
Hélène Lê, Jules Deforges, Guoqiang Hua, Ysia Idoux-Gillet, Charlotte Ponté, Véronique Lindner, Anne Olland, Pierre-Emanuel Falcoz, Cécile Zaupa, Shreyansh Jain, Eric Quéméneur, Nadia Benkirane-Jessel, Jean-Marc Balloul
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108094- (2023)
Summary: This work describes a patient-derived tumoroid model (PDTs) to support precision medicine in lung oncology. The use of human adipose tissue-derived microvasculature and patient-derived peripheral blood mononuclear cells (PBMCs) permits to ac
Externí odkaz:
https://doaj.org/article/f04495021d784eabb48ecdf7bddeee29
Autor:
Laetitia Fend, Eric Quemeneur, Monika Semmrich, Jean-Baptiste Marchand, Matilda Rehn, Nathalie Silvestre, Linda Mårtensson, Johann Foloppe, Ingrid Teige, Björn Frendeus, Petra Holmkvist, Carolin Svensson, Christelle Remy, Patricia Kleinpeter, Jules Deforges, Fred Junghus, Kirstie L Cleary, Mimoza Bodén
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/715bfd92355a4c01a650b6be33e6abb9
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-17 (2019)
Abstract Background Long intergenic non-coding RNAs (lincRNAs) can act as regulators of expression of protein-coding genes. Trans-natural antisense transcripts (trans-NATs) are a type of lincRNAs that contain sequence complementary to mRNA from other
Externí odkaz:
https://doaj.org/article/1cf4a0fac1d44603980180ea426c9ded
Autor:
Ghazanfar Abbas Khan, Jules Deforges, Rodrigo S Reis, Yi-Fang Hsieh, Jonatan Montpetit, Wojciech Antosz, Luca Santuari, Christian S Hardtke, Klaus D Grasser, Yves Poirier
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008732 (2020)
Transcription termination has important regulatory functions, impacting mRNA stability, localization and translation potential. Failure to appropriately terminate transcription can also lead to read-through transcription and the synthesis of antisens
Externí odkaz:
https://doaj.org/article/de9b24e55b2f43aeb703628591f84efa
Autor:
Clémentine Delan-Forino, Jules Deforges, Lionel Benard, Bruno Sargueil, Marie-Christine Maurel, Claire Torchet
Publikováno v:
Viruses, Vol 6, Iss 2, Pp 489-506 (2014)
Viroids are small pathogenic circular single-stranded RNAs, present in two complementary sequences, named plus and minus, in infected plant cells. A high degree of complementarities between different regions of the RNAs allows them to adopt complex s
Externí odkaz:
https://doaj.org/article/30d39edfaf1a42fa86a0c4ef724df0a3
Autor:
Yves Poirier, Thomas Dresselhaus, Jules Deforges, Wojciech Antosz, Kevin Begcy, Astrid Bruckmann, Klaus D. Grasser
Publikováno v:
Plant Cell
The Plant Cell, vol. 32, no. 5, pp. 1449-1463
The Plant Cell, vol. 32, no. 5, pp. 1449-1463
Transcript elongation factors associate with elongating RNA polymerase II (RNAPII) to control the efficiency of mRNA synthesis and consequently modulate plant growth and development. Encountering obstacles during transcription such as nucleosomes or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083e8898abe270e0a4029911aacd31d0
https://doi.org/10.1105/tpc.19.00891
https://doi.org/10.1105/tpc.19.00891
Autor:
Lucas Walther, Caroline Tosch, Jules Deforges, Christine Carapito, Magali Rompais, Marie-Christine Claudepierre, Nathalie Silvestre, Kaïdre Bendjama, Eric Quemeneur, Jacky Goetz, Vincent Hyenne, Karola Rittner
Publikováno v:
Cancer Research. 83:697-697
Virus-based therapies show promise in inducing systemic anti-tumor immunity. Over the past years, modified poxviruses were developed to induce a sustained antitumoral immune response. Several studies confirm this hypothesis and report induction of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e10a2154fee5ec2aecf7e6b5565cb8b
https://doi.org/10.1158/1538-7445.am2023-697
https://doi.org/10.1158/1538-7445.am2023-697
Autor:
Philippe Erbs, Annie Findeli, Johann Foloppe, Juliette Kempf, Isabelle Farine, Baptiste Moreau, Julie Hortelano, Christelle Pichon, Jules Deforges, Eric Quemeneur
Publikováno v:
Cancer Research. 83:6796-6796
Oncolytic virus (OV) therapy has emerged as a promising approach for cancer treatment with the potential to be less toxic and more efficient than classic cancer therapies. Various types of OVs in clinical development, including Vaccinia virus (VACV)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::486168b7be0dae9647bd796f09e698bc
https://doi.org/10.1158/1538-7445.am2023-6796
https://doi.org/10.1158/1538-7445.am2023-6796