Study Design of the Phase 3 Sparsentan Versus Irbesartan (DUPLEX) Study in Patients With Focal Segmental Glomerulosclerosis

Autor: Ulysses Diva, Radko Komers, William E. Rote, Andrea Loewen, Howard Trachtman, Jula K. Inrig

Publikováno v: Kidney International Reports, Vol 5, Iss 4, Pp 494-502 (2020)
Kidney International Reports

Introduction: Focal segmental glomerulosclerosis (FSGS), a histologic lesion in the kidney caused by varied pathophysiological processes, leads to end-stage kidney disease in a large proportion of patients. Sparsentan is a first-in-class orally activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cce3450b96edfd9b2d4decbb2a4742
https://doi.org/10.1016/j.ekir.2019.12.017

There's no place like home: 35-year patient survival on home hemodialysis

Autor: Anna Jin, Jerry Z. Yu, Wei Ling Lau, Alex Li, Connie M. Rhee, Uttam Reddy, Antoney Ferrey, Kamyar Kalantar-Zadeh, Yongen Chang, Jula K. Inrig, Jason A. Chou

Publikováno v: Seminars in Dialysis. 31:300-304

The vast majority of maintenance dialysis patients suffer from poor long-term survival rates and lower levels of health-related quality of life. However, home hemodialysis is a historically significant dialysis modality that has been associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a07bbd07aff8c8710476f7b4f0117d
https://doi.org/10.1111/sdi.12660

Extracellular Volume Overload and Increased Vasoconstriction in Patients With Recurrent Intradialytic Hypertension

Autor: Javier A. Neyra, Yunyun Zhou, Wanpen Vongpatanasin, Guanghua Xiao, Peter N. Van Buren, Jula K. Inrig, Robert D. Toto

Publikováno v: Kidney & Blood Pressure Research, Vol 41, Iss 6, Pp 802-814 (2016)
Kidney & blood pressure research

Background/Aims: Intradialytic hypertension (IH) occurs frequently in some hemodialysis patients and increases mortality risk. We simultaneously compared pre-dialysis, post-dialysis and changes in extracellular volume and hemodynamics in recurrent IH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373f724ef31b0ea80b128cc30b305fcf
http://www.karger.com/Article/FullText/450565

Comparison of Ambulatory Blood Pressure Patterns in Patients With Intradialytic Hypertension and Hemodialysis Controls

Autor: Guanghua Xiao, Catherine Hompesch, Lindsay Ripley, Tsung Wei Ma, Javier A. Neyra, Jula K. Inrig, Robert D. Toto, Peter N. Van Buren

Publikováno v: Kidney & blood pressure research
Kidney & Blood Pressure Research, Vol 41, Iss 3, Pp 240-249 (2016)

Background/Aims: Intradialytic hypertension (IH) patients have higher mortality risk than other hemodialysis patients and have been shown to have higher ambulatory blood pressure (BP). We hypothesized that interdialytic BP patterns would differ in IH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608b9bac5ca68a2ab0cc12173b613334
http://europepmc.org/articles/PMC4919278

Intradialytic hypotension, blood pressure changes and mortality risk in incident hemodialysis patients

Autor: Csaba P. Kovesdy, Jason A. Chou, Yoshitsugu Obi, Danh V. Nguyen, Kamyar Kalantar-Zadeh, Jula K. Inrig, Elani Streja, John J. Sim, Alpesh Amin, Connie M. Rhee

Publikováno v: Chou, JA; Streja, E; Nguyen, DV; Rhee, CM; Obi, Y; Inrig, JK; et al.(2018). Intradialytic hypotension, blood pressure changes and mortality risk in incident hemodialysis patients. NEPHROLOGY DIALYSIS TRANSPLANTATION, 33(1), 149-159. doi: 10.1093/ndt/gfx037. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5619t55v

Intradialytic hypotension (IDH) occurs frequently in maintenance hemodialysis (HD) patients and may be associated with higher mortality. We hypothesize that nadir intradialytic systolic blood pressure (niSBP) is inversely related to death risk while

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18f717ae3a71d46ebd5b5d07d6b7563
https://europepmc.org/articles/PMC5837776/