Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Jukka Kero"'
Autor:
Markus Eszlinger, Alexandra Stephenson, Shideh Mirhadi, Konrad Patyra, Michael F Moran, Moosa Khalil, Jukka Kero, Ralf Paschke
Publikováno v:
European Thyroid Journal, Vol 12, Iss 6, Pp 1-13 (2023)
Objective: Nonautoimmune hyperthyroidism (NAH) is rare and occurs due to a constitutively activating thyroid stimulating hormone receptor (TSHR) mutation. In contrast to other thyroid nodules, no further evaluation for malignancy is recommended for h
Externí odkaz:
https://doaj.org/article/ec09ffec7d2645cb934c4d925b01088d
Autor:
Maria Månsson Martinez, Lampros Spiliopoulos, Falastin Salami, Daniel Agardh, Jorma Toppari, Åke Lernmark, Jukka Kero, Riitta Veijola, Päivi Tossavainen, Sauli Palmu, Markus Lundgren, Henrik Borg, Anastasia Katsarou, Helena Elding Larsson, Mikael Knip, Marlena Maziarz, Carina Törn, and the TEDDY-Family (TEFA) Study Group
Publikováno v:
Clinical Diabetes and Endocrinology, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Background Individuals with multiple islet autoantibodies are at increased risk for clinical type 1 diabetes and may proceed gradually from stage to stage complicating the recruitment to secondary prevention studies. We evaluated multiple is
Externí odkaz:
https://doaj.org/article/633ec09640614810b01fefb6b4393c39
Autor:
Junguee Lee, Ki Cheol Park, Hae Joung Sul, Hyun Jung Hong, Kun-Ho Kim, Jukka Kero, Minho Shong
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The primary cilium is well-preserved in human differentiated thyroid cancers such as papillary and follicular carcinoma. Specific thyroid cancers such as Hürthle cell carcinoma, oncocytic variant of papillary thyroid carcinoma (PTC), and PT
Externí odkaz:
https://doaj.org/article/7690e024f6ab4de3af52ee9ea641e697
Autor:
Elin Schoultz, Ellen Johansson, Carmen Moccia, Iva Jakubikova, Naveen Ravi, Shawn Liang, Therese Carlsson, Mikael Montelius, Konrad Patyra, Jukka Kero, Kajsa Paulsson, Henrik Fagman, Martin O. Bergo, Mikael Nilsson
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 2 (2022)
Cancer cells hijack developmental growth mechanisms but whether tissue morphogenesis and architecture modify tumorigenesis is unknown. Here, we characterized a new mouse model of sporadic thyroid carcinogenesis based on inducible expression of BRAF c
Externí odkaz:
https://doaj.org/article/508f6d6970624701985ec7553bd80cdf
Autor:
Konrad Patyra, Kristiina Makkonen, Maria Haanpää, Sinikka Karppinen, Liisa Viikari, Jorma Toppari, Mary Pat Reeve, Jukka Kero
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundCentral hypothyroidism (CeH) is a rare condition affecting approximately 1:16 000- 100 000 individuals. Congenital forms can harm normal development if not detected and treated promptly. Clinical and biochemical diagnosis, especially of iso
Externí odkaz:
https://doaj.org/article/2256a7c84fa24fdeb2ace175347017f7
Autor:
Maria Månsson Martinez, Falastin Salami, Helena Elding Larsson, Jorma Toppari, Åke Lernmark, Jukka Kero, Riitta Veijola, Jaakko J Koskenniemi, Päivi Tossavainen, Markus Lundgren, Henrik Borg, Anastasia Katsarou, Marlena Maziarz, Carina Törn, The TEDDY Family (TEFA) Study Group
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 4, Iss 2, Pp n/a-n/a (2021)
Abstract Aim The aim of the present study was to assess beta cell function based on an oral glucose tolerance test (OGTT) in participants with single islet autoantibody or an intravenous glucose tolerance test (IvGTT) in participants with multiple is
Externí odkaz:
https://doaj.org/article/bddbd4e3339249d09d5b970db5d22bf5
Autor:
Emmi Danner, Laura Niuro, Hanna Huopio, Harri Niinikoski, Liisa Viikari, Jukka Kero, Jarmo Jääskeläinen
Publikováno v:
Pediatric Research. 93:649-653
Background A rise in the incidence of congenital hypothyroidism (CH) has been reported worldwide. This nationwide study aimed to describe the secular trends and current incidence of CH in Finland. Methods Two independent study cohorts, a national and
Autor:
Konrad Patyra, Christoffer Löf, Holger Jaeschke, Hendrik Undeutsch, Huifei Sophia Zheng, Sofia Tyystjärvi, Kamila Puławska, Milena Doroszko, Marcin Chruściel, Britt-Marie Loo, Riikka Kurkijärvi, Fu-Ping Zhang, Chen-Che Jeff Huang, Claes Ohlsson, Andreina Kero, Matti Poutanen, Jorma Toppari, Ralf Paschke, Nafis Rahman, Ilpo Huhtaniemi, Jarmo Jääskeläinen, Jukka Kero
Publikováno v:
Thyroid
BACKGROUND: The human adrenal cortex undergoes several rapid remodeling steps during its lifetime. In rodents, similar remodeling occurs postnatally in the “X-zone” layer through unknown mechanisms. Furthermore, little is known regarding the impa
Autor:
Jukka Kero, Jaakko J. Koskenniemi, Sara Karsikas, Tytti Pokka, Olivia Lou, Jorma Toppari, Riitta Veijola
Publikováno v:
Diabetic Medicine. 39
Autor:
Jukka, Kero, Jaakko J, Koskenniemi, Sara, Karsikas, Tytti, Pokka, Olivia, Lou, Jorma, Toppari, Riitta, Veijola
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 39(10)
β-cell stress and dysfunction may contribute to islet autoimmunity and progression to clinical type 1 diabetes. We present a protocol of three randomised controlled trials assessing the effects of glucagon-like peptide 1 (GLP - 1) analogue liragluti