Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Jukka, Jernvall"'
Autor:
Zachary T. Calamari, Andrew Song, Emily Cohen, Muspika Akter, Rishi Das Roy, Outi Hallikas, Mona M. Christensen, Pengyang Li, Pauline Marangoni, Jukka Jernvall, Ophir D. Klein
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Continuously growing teeth are an important innovation in mammalian evolution, yet genetic regulation of continuous growth by stem cells remains incompletely understood. Dental stem cells responsible for tooth crown growth are los
Externí odkaz:
https://doaj.org/article/7016d160d0634ccd86d7e97904abdff2
Autor:
Qiang Lan, Ewelina Trela, Riitta Lindström, Jyoti Prabha Satta, Beata Kaczyńska, Mona M Christensen, Martin Holzenberger, Jukka Jernvall, Marja L Mikkola
Publikováno v:
eLife, Vol 13 (2024)
The mammary gland is a unique organ that undergoes dynamic alterations throughout a female’s reproductive life, making it an ideal model for developmental, stem cell and cancer biology research. Mammary gland development begins in utero and proceed
Externí odkaz:
https://doaj.org/article/7481288197854bb1bc630a34b23a8629
Autor:
Elis Newham, Pamela G. Gill, Michael J. Benton, Philippa Brewer, Neil J. Gostling, David Haberthür, Jukka Jernvall, Tuomas Kankanpää, Aki Kallonen, Charles Navarro, Alexandra Pacureanu, Kelly Richards, Kate Robson Brown, Philipp Schneider, Heikki Suhonen, Paul Tafforeau, Katherine Williams, Berit Zeller-Plumhoff, Ian J. Corfe
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/5b70894d226842fb9cf18bd6265e3763
Autor:
Ana-Marija Sulic, Rishi Das Roy, Verdiana Papagno, Qiang Lan, Riikka Saikkonen, Jukka Jernvall, Irma Thesleff, Marja L. Mikkola
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112643- (2023)
Summary: Morphogenesis of ectodermal organs, such as hair, tooth, and mammary gland, starts with the formation of local epithelial thickenings, or placodes, but it remains to be determined how distinct cell types and differentiation programs are esta
Externí odkaz:
https://doaj.org/article/d376cbf43e3543e89035159addf00af1
Autor:
Elis Newham, Pamela G. Gill, Philippa Brewer, Michael J. Benton, Vincent Fernandez, Neil J. Gostling, David Haberthür, Jukka Jernvall, Tuomas Kankaanpää, Aki Kallonen, Charles Navarro, Alexandra Pacureanu, Kelly Richards, Kate Robson Brown, Philipp Schneider, Heikki Suhonen, Paul Tafforeau, Katherine A. Williams, Berit Zeller-Plumhoff, Ian J. Corfe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Modern mammals are endothermic, but it has not been clear when this type of metabolism evolved. Here, Newham et al. analyse tooth and bone structure in Early Jurassic stem-mammal fossils to estimate lifespan and blood flow rates, which inform about b
Externí odkaz:
https://doaj.org/article/0f790beb0bdd40d7b1a463e0dbcc0bc1
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1008947 (2021)
Although most genes share their chromosomal neighbourhood with other genes, distribution of genes has not been explored in the context of individual organ development; the common focus of developmental biology studies. Because developmental processes
Externí odkaz:
https://doaj.org/article/abd8028eef474f2b9853a1fd277cb7e7
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 12, p e1008436 (2020)
A major challenge in evolutionary developmental biology is to understand how genetic mutations underlie phenotypic changes. In principle, selective pressures on the phenotype screen the gene pool of the population. Teeth are an excellent model for un
Externí odkaz:
https://doaj.org/article/bc8b3d1c39ee47c3ab5855399cf0daca
Autor:
Tarja Sundell, Juhana I. Kammonen, Ella Mustanoja, Vincent Biard, Mervi Kunnasranta, Marja Niemi, Milaja Nykänen, Tommi Nyman, Jukka U. Palo, Mia Valtonen, Lars Paulin, Jukka Jernvall, Petri Auvinen
Publikováno v:
Conservation Genetics. 24:155-165
Fragmentation of isolated populations increases the risk of inbreeding and loss of genetic diversity. The endemic Saimaa ringed seal (Pusa hispida saimensis) is one of the most endangered pinnipeds in the world with a population of only ~ 400 individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db1b5d82b6a4d391f4172110a2e3f8f
https://doi.org/10.1007/s10592-022-01497-9
https://doi.org/10.1007/s10592-022-01497-9
Autor:
Juliana FELTRIN-SOUZA, Fabiano JEREMIAS, Satu ALALUUSUA, Carin SAHLBERG, Lourdes SANTOS-PINTO, Jukka JERNVALL, Susanna SOVA, Rita de Cássia Loiola CORDEIRO, Paulo Sérgio CERRI
Publikováno v:
Brazilian Oral Research, Vol 34 (2020)
Abstract The exposure to amoxicillin has been associated with molar incisor hypomineralization. This study aimed to determine if amoxicillin disturbs the enamel mineralization in in vivo experiments. Fifteen pregnant rats were randomly assigned into
Externí odkaz:
https://doaj.org/article/7921557aed4340da9dc575cf88b02ae2
Autor:
Teemu J Häkkinen, S Susanna Sova, Ian J Corfe, Leo Tjäderhane, Antti Hannukainen, Jukka Jernvall
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 5, p e1007058 (2019)
The most mineralized tissue of the mammalian body is tooth enamel. Especially in species with thick enamel, three-dimensional (3D) tomography data has shown that the distribution of enamel varies across the occlusal surface of the tooth crown. Differ
Externí odkaz:
https://doaj.org/article/c748d91f58d54acf89ec6788737306ca