Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jukiya Sakamoto"'
Autor:
Akiho Yoshidome, Jukiya Sakamoto, Mizuki Kohara, Shinya Shiomi, Mako Hokaguchi, Yuki Hitora, Mariko Kitajima, Sachiko Tsukamoto, Hayato Ishikawa
Publikováno v:
Organic Letters. 25:347-352
Divergent total syntheses of the hetero-oligomeric iridoid glycosides mainly found in
Publikováno v:
Chemical and Pharmaceutical Bulletin. 70:662-668
A number of alkaloids found in Mitragyna species belonging to the Rubiaceae family have been shown to have potent biological activity such as analgesic properties. Here, we report the asymmetric total syntheses of mitragynine, speciogynine, and 7-hyd
Autor:
Hayato Ishikawa, Jukiya Sakamoto
Publikováno v:
Synlett.
The preparation of natural product libraries by total synthesis has become an extremely important and attractive research topic in organic chemistry. In higher plants, secologanin, which belongs to the monoterpene family, is the starting point for de
Publikováno v:
Synlett.
The collective and efficient asymmetric total syntheses of five β-carboline-type monoterpenoid indole alkaloid glycosides were achieved in fewer than thirteen steps. A Pictet–Spengler reaction with α-cyanotryptamine followed by the removal of the
Publikováno v:
Chemistry – A European Journal. 29
Publikováno v:
Chemistry – A European Journal. 29
Autor:
Nanako Nakashima, Jukiya Sakamoto, Kenta Rakumitsu, Mariko Kitajima, Lia Dewi Juliawaty, Hayato Ishikawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 70:187-191
A new pentacyclic monoterpenoid indole alkaloid glycoside named secorubenine (1) was isolated from the heartwood of Adina rubescens, collected in Indonesia. The structure was elucidated by spectroscopic analysis and chemical modification of isolated
Autor:
Jukiya Sakamoto, Hayato Ishikawa
Publikováno v:
Chemistry – A European Journal. 28
Publikováno v:
Angewandte Chemie. 132:13516-13524
A collective synthesis of glycosylated monoterpenoid indole alkaloids is reported. A highly diastereoselective Pictet-Spengler reaction with α-cyanotryptamine and secologanin tetraacetate as substrates, followed by a reductive decyanation reaction,
Autor:
Jukiya Sakamoto, Hayato Ishikawa
Publikováno v:
Chemistry – A European Journal. 28
A series of bioinspired transformations that are applied to convert strictosidine aglycones into monoterpenoid indole alkaloids is reported. The highly reactive key intermediates, strictosidine aglycones, were prepared in situ by simple removal of a