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14C-labelled adamantyltripeptides were prepared. The pharmacokinetics of immunomodulatory adamantyltripeptides (isomers 1 and 2) was investigated. The results showed evident differences in the distribution of adamantyltripeptide isomers in various or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::082c76987f8e62b4cec8b20b8634d9aa
https://www.bib.irb.hr/254361
https://www.bib.irb.hr/254361
Biological activity of two novel adamantyltripeptides, D-(adamant-2-yl)-glycyl-L-alanyl-D-isoglutamine (AdTP1) and L-(adamant-2-yl)-glycyl-L-alanyl-D-isoglutamine (AdTP2) was studied. Immunostimulating activity was detected in mice immunized with she
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::e317b3f2d58168987c1838b1e22f1eb3
https://www.bib.irb.hr/254654
https://www.bib.irb.hr/254654
Autor:
Forčić, Dubravko, Dašić, Gorana, Vranešić, Branka, Treščec, Anđa, Jukić, Ruža, Tomašić, Jelka, Rabatić, Sabina, Mažuran, Reanata
Mice were immunized with tetanus toxoid (TT) and with adamatyltripeptides (AdTPs) or Al phosphate, respectively. Both isomers of AdTP and Al phosphate stimulated the antibody production, downregulated the expression of total gamma-delta T cells. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::28a228415481701fef61a74ccce0a9a7
https://www.bib.irb.hr/254091
https://www.bib.irb.hr/254091
Peptidoglycan monomer derivatives (Boc-Tyr-PGM and adamantylacetyl-PGM) were a good substrates for N-acetylmuramyl-L-alanine amidase, but adamantyltripeptides did not undergo hydrolysis with this enzyme.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::6ad1f3c89681f850c9465a41dbdebb24
https://www.bib.irb.hr/254589
https://www.bib.irb.hr/254589
Određivanje apsolutne konfiguracije adamantilglicina u novim biološki aktivnim adamantiltripeptidima
L-Ala-D-isoGln was linked to D, L-(2-adamantyl)-Gly yielding two stereoisomers of (2-adamantyl)-Gly-L-Ala-D-iso-Gln regarding glycine moiety. Stereoisomers were easily separated on a Silicagel column.The glycine moiety configuration was assignated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::f4cfe4a523a08dda41936ae688c0cdb8
https://www.bib.irb.hr/255680
https://www.bib.irb.hr/255680
Autor:
Horvat, Štefica, Varga-Defterdarovič, Lidija, Horvat, Jaroslav, Jukić, Ruža, Kantoci, Darko, Chung, Nga N., Schiller, Peter W., Biesert, Lothar, Pfützner, Andreas, Suhartono, Haryadi, Rübsamen-Waigmann, Helga
Publikováno v:
Journal of Peptide Science; Sep1995, Vol. 1 Issue 5, p303-310, 8p
