Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jujiao Kang"'
Autor:
Runye Shi, Shitong Xiang, Tianye Jia, Trevor W. Robbins, Jujiao Kang, Tobias Banaschewski, Gareth J. Barker, Arun L. W. Bokde, Sylvane Desrivières, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Rüdiger Brühl, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Luise Poustka, Sarah Hohmann, Sabina Millenet, Juliane H. Fröhner, Michael N. Smolka, Nilakshi Vaidya, Henrik Walter, Robert Whelan, Gunter Schumann, Xiaolei Lin, Barbara J. Sahakian, Jianfeng Feng, IMAGEN Consortium
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Adolescents exhibit remarkable heterogeneity in the structural architecture of brain development. However, due to limited large-scale longitudinal neuroimaging studies, existing research has largely focused on population averages, and the ne
Externí odkaz:
https://doaj.org/article/e45bba7217f1486e9927d8dfce00ad3e
Autor:
Liu Yang, Ya-Nan Ou, Bang-Sheng Wu, Wei-Shi Liu, Yue-Ting Deng, Xiao-Yu He, Yi-Lin Chen, Jujiao Kang, Chen-Jie Fei, Ying Zhu, Lan Tan, Qiang Dong, Jianfeng Feng, Wei Cheng, Jin-Tai Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The genetic contribution of protein-coding variants to immune-mediated diseases (IMDs) remains underexplored. Through whole exome sequencing of 40 IMDs in 350,770 UK Biobank participants, we identified 162 unique genes in 35 IMDs, among whic
Externí odkaz:
https://doaj.org/article/0382ad71c24141108a559c2764251661
Autor:
Jujiao Kang, Yue-Ting Deng, Bang-Sheng Wu, Wei-Shi Liu, Ze-Yu Li, Shitong Xiang, Liu Yang, Jia You, Xiaohong Gong, Tianye Jia, Jin-Tai Yu, Wei Cheng, Jianfeng Feng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Alcohol consumption is a heritable behavior seriously endangers human health. However, genetic studies on alcohol consumption primarily focuses on common variants, while insights from rare coding variants are lacking. Here we leverage whole
Externí odkaz:
https://doaj.org/article/3832146c44b04cd79a8c03aea949af79
Autor:
Weikang Gong, Yan Fu, Bang-Sheng Wu, Jingnan Du, Liu Yang, Ya-Ru Zhang, Shi-Dong Chen, JuJiao Kang, Ying Mao, Qiang Dong, Lan Tan, Jianfeng Feng, Wei Cheng, Jin-Tai Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Iron plays a fundamental role in multiple brain disorders. However, the genetic underpinnings of brain iron and its implications for these disorders are still lacking. Here, we conduct an exome-wide association analysis of brain iron, measur
Externí odkaz:
https://doaj.org/article/7500d4213dad4a99afb9f86430992acc
Autor:
Xiao-Yu He, Bang-Sheng Wu, Liu Yang, Yu Guo, Yue-Ting Deng, Ze-Yu Li, Chen-Jie Fei, Wei-Shi Liu, Yi-Jun Ge, Jujiao Kang, Jianfeng Feng, Wei Cheng, Qiang Dong, Jin-Tai Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Previous genetic studies of venous thromboembolism (VTE) have been largely limited to common variants, leaving the genetic determinants relatively incomplete. We performed an exome-wide association study of VTE among 14,723 cases and 334,315
Externí odkaz:
https://doaj.org/article/52e2d900e96d4b37bc1c83682135fd19
Autor:
Nanyu Kuang, Zhaowen Liu, Gechang Yu, Xinran Wu, Benjamin Becker, Huaxin Fan, Songjun Peng, Kai Zhang, Jiajia Zhao, Jujiao Kang, Guiying Dong, Xingming Zhao, Barbara J. Sahakian, Trevor W. Robbins, Wei Cheng, Jianfeng Feng, Gunter Schumann, Lena Palaniyappan, Jie Zhang
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Comorbidity is the rule rather than the exception for childhood and adolescent onset mental disorders, but we cannot predict its occurrence and do not know the neural mechanisms underlying comorbidity. We investigate if the effect
Externí odkaz:
https://doaj.org/article/b154f869045b4c3bb8ccfbfe491e818b
Autor:
Hui-Fu Wang, Wei Zhang, Edmund T. Rolls, Yuzhu Li, Linbo Wang, Ya-Hui Ma, Jujiao Kang, Jianfeng Feng, Jin-Tai Yu, Wei Cheng
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104336- (2022)
Summary: Background: Hearing impairment was recently identified as the most prominent risk factor for dementia. However, the mechanisms underlying the link between hearing impairment and dementia are still unclear. Methods: We investigated the associ
Externí odkaz:
https://doaj.org/article/0f391d64bc0449dca778538b92c05273
Autor:
Zeyu Jiao, Yinglei Lai, Jujiao Kang, Weikang Gong, Liang Ma, Tianye Jia, Chao Xie, Shitong Xiang, Wei Cheng, Andreas Heinz, Sylvane Desrivières, Gunter Schumann, Fengzhu Sun, Jianfeng Feng
Publikováno v:
NeuroImage, Vol 255, Iss , Pp 119166- (2022)
Magnetic Resonance Imaging (MRI) technology has been increasingly used in neuroscience studies. Reproducibility of statistically significant findings generated by MRI-based studies, especially association studies (phenotype vs. MRI metric) and task-i
Externí odkaz:
https://doaj.org/article/b7b07e2abbc046dbb6620ae40ed9a92c
Publikováno v:
Neurology; 8/13/2024, Vol. 103 Issue 3, p1-13, 13p
Autor:
Chun Shen, Edmund T. Rolls, Wei Cheng, Jujiao Kang, Guiying Dong, Chao Xie, Xing-Ming Zhao, Barbara J. Sahakian, Jianfeng Feng
Publikováno v:
Neurology. 99:e164-e175
Background and ObjectivesTo investigate the independent associations of social isolation and loneliness with incident dementia and to explore the potential neurobiological mechanisms.MethodsWe utilized the UK Biobank cohort to establish Cox proportio