Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Juji Dai"'
Autor:
Rulu Pan, Juji Dai, Weicheng Liang, Hongxiao Wang, Lin Ye, Siqi Ye, Ziqi Lin, Shishun Huang, Yan Xiong, Li Zhang, Liting Lu, Ouchen Wang, Xian Shen, Wanqin Liao, Xincheng Lu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 6, Pp 1-13 (2023)
Abstract Phosphodiesterase 4D interacting protein (PDE4DIP) is a centrosome/Golgi protein associated with cyclic nucleotide phosphodiesterases. PDE4DIP is commonly mutated in human cancers, and its alteration in mice leads to a predisposition to inte
Externí odkaz:
https://doaj.org/article/74f1109b36344deda1747e769804eea6
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Abstract Cetuximab is approved for the treatment of metastatic colorectal cancer (mCRC) with RAS wild-type. Nevertheless, the prognosis remains poor and the effectiveness of cetuximab is limited in KRAS mutant mCRC. Recently, emerging evidence has sh
Externí odkaz:
https://doaj.org/article/c2181e41f0cc462294e76d04f119e6f0
Autor:
Rulu Pan, Yan Yu, Haiyan Zhu, Wenyi Zhang, Yuan Qin, Lin Ye, Juji Dai, Ren Huang, Xinyan Peng, Siqi Ye, Ziqi Lin, Shishun Huang, Shuyi Chong, Liting Lu, Xincheng Lu
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105184- (2022)
Summary: R-spondin 2 (RSPO2) drives the potentiation of Wnt signaling and is implicated in tumorigenesis in multiple cancers, but its role in ovarian cancer has not been investigated. Here, we reported that RSPO2 promoted the growth and metastasis of
Externí odkaz:
https://doaj.org/article/312c0b9a0427475aa5958156463f533a
Autor:
Zhu Zhao, Juji Dai, Yan Yu, Qian Zhang, Sai Liu, Guanmeng Huang, Zheng Zhang, Tianke Chen, Rulu Pan, Liting Lu, Wenyi Zhang, Wanqin Liao, Xincheng Lu
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Animal models play crucial roles in the development of anticancer therapeutics. The ability to quickly assess the localized primary hepatocellular carcinoma (HCC) status in a non-invasive manner would significantly improve the effectiveness of anti-H
Externí odkaz:
https://doaj.org/article/4e85c5fd350c41fe9e8c68f5875665a4
Publikováno v:
Biochemical and Biophysical Research Communications. 656:63-69
Autor:
Juji Dai, Yangyang Fu
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:4698-4709
Necroptosis is a programmed necrosis in a caspase-independent fashion. The role of necroptosis-related genes (NRGs) in lung cancer remains unknow. Herein, we classified TCGA-LUAD cohort into two necroptosis-related subtypes (C1 and C2) by consensus c
A Novel Pyroptosis-Associated Gene Signature to Predict Prognosis in Patients with Colorectal Cancer
Publikováno v:
Evidence-based complementary and alternative medicine : eCAM. 2022
Background. Pyroptosis is a form of cell death characterized by cell swelling and plasma membrane bubbling in association with inflammatory and immune responses. To date, the association between pyroptosis and colorectal cancer remains unclear. We ai
Autor:
Yuan, Qin, Kai, Wu, Zheng, Zhang, Rulu, Pan, Ziqi, Lin, Wenyi, Zhang, Shishun, Huang, Juji, Dai, Ren, Huang, Siqing, Gong, Huan, Lin, Shuyi, Chong, Liting, Lu, Xincheng, Lu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1868:166518
Cutaneous wound healing is a complicated process that is characterized by an initial inflammatory phase followed by a proliferative phase. NLRC3 plays important roles in innate immunity, inflammatory regulation and tumor cell growth. However, the fun
Autor:
Li Zhang, Liting Lu, Rulu Pan, Tianke Chen, Jin Hu, Zhu Zhao, Wanqin Liao, Xiaowei Dai, Juji Dai, Mei Lu, Yalei Qi, Zhanyu Wang, Chaodong Ding, Ziqi Lin, Xincheng Lu, Zheng Zhang
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 10, Pp 1-15 (2020)
Cell Death and Disease, Vol 11, Iss 10, Pp 1-15 (2020)
Hepatocellular carcinoma (HCC) is a major leading cause of cancer-related death worldwide. Alpha fetoprotein (AFP) is reactivated in a majority of hepatocellular carcinoma (HCC) and associated with poor patient outcomes. Although increasing evidence
Publikováno v:
Cancer Medicine
Sodium butyrate (NaBu) and sodium 4‐phenylbutyrate (4PBA) have promising futures in cancer treatment; however, their underlying molecular mechanisms are not clearly understood. Here, we show A549 cell death induced by NaBu and 4PBA are not the same