Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Juichiro Shimizu"'
Autor:
Yutaka Kitagawa, Yamato Tamura, Juichiro Shimizu, Chikako Nakajima-Takenaka, Shigeki Taniguchi, Shinichi Uesato, Miyako Takaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 2, Pp 167-175 (2007)
The aim of the present study was performed to determine whether a novel histone deacetylase (HDAC) inhibitor, N-(2-aminophenyl)-4-{[benzyl(2-hydroxyethyl)amino]methyl} benzamide (K-183), prevents a reversible cardiac hypertrophy induced by isoprotere
Externí odkaz:
https://doaj.org/article/db590ffb12ac44549caab1c0f6851d56
Publikováno v:
Journal of Clinical Imaging Science. Aug2022, Vol. 12, p1-7. 7p.
Autor:
Hiroshi Date, Noriyuki Kataoka, Tetsuya Ikeda, Juichiro Shimizu, Hiroshi Morita, Seiichi Mochizuki, Fumihiko Kajiya, Aya Miura, Kazufumi Nakamura, Ken Hashimoto, Satoshi Mohri, Kengo Fukushima Kusano, Satoshi Nagase, Aiko Ogawa, Katsushi Hashimoto, Keiko Ohta-Ogo, Hiromi Matsubara, Hideki Fujio, Tohru Ohe
Publikováno v:
International Journal of Cardiology. 140:102-107
Background Idiopathic pulmonary arterial hypertension (IPAH) is a disease characterized by progressively increased resistance of pulmonary arteries. In this study, we evaluated the mechanical property of single pulmonary artery smooth muscles cells (
Publikováno v:
The Journal of Physiological Sciences. 59:75-80
The external work (EW) efficiency of individual arrhythmic beats of the left ventricle (LV) cannot directly be obtained since LV O(2) consumption (VO(2)) of each beat cannot directly be measured under beat-to-beat varying contractile and loading cond
Autor:
Miyako Takaki, Juichiro Shimizu, Bongju Kim, Hiromi Misawa, Kiyoe Tohne, Chikako Nakajima-Takenaka, Satoshi Matsuoka, Ayako Takeuchi, Daisuke Yamashita
Publikováno v:
The Journal of Physiological Sciences. 59:63-74
The goal of our study was to evaluate the origin of the increased O(2) consumption in electrically stimulated left ventricular slices of isoproterenol-induced hypertrophied rat hearts with normal left ventricular pressure. O(2) consumption per minute
Publikováno v:
Cardiovascular Research. 81:389-399
Aims The present study is designed to investigate the role of neuronal nitric oxide synthase (nNOS) in the regulation of vascular mitogen-activated protein kinase (MAPK) activity under basal and angiotensin II (Ang II)-stimulated conditions. Methods
Autor:
Shigeho MoritaS. Morita, Ju Mizuno, Hiromi Matsubara, Juichiro Shimizu, Kazuo Hanaoka, Junichi Araki, Satoshi Mohri, Robert AkinsR. Akins, Takeshi Mikane, Shunsuke SuzukiS. Suzuki
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 86:78-87
Temperature changes influence cardiac diastolic function. The monoexponential time constant (tauE), which is a conventional lusitropic index of the rate of left ventricular (LV) pressure fall, increases with cooling and decreases with warming. We hav
Autor:
Chikako Nakajima-Takenaka, Daisuke Yamashita, Daisuke Takeshita, Miyako Takaki, Haruo Ito, Kiyoe Tohne, Yutaka Kitagawa, Juichiro Shimizu
Publikováno v:
The Journal of Physiological Sciences. 58:179-188
In consideration of clinical implications, it is often complained that short-term experimental diseased heart models do not mimic long-term diseased hearts that are often clinically encountered. The aim of the present study was (i) to compare the lef
Autor:
Kousuke Endo, Keiji Naruse, Tatsuo Iwasaki, Satoshi Mohri, Masanori Hirota, Toyotaka Yada, Juichiro Shimizu, Taro Morimoto, Yousuke Inai, Fumihiko Kajiya, Yasuo Ogasawara, Masahito Kajiya, Takahiko Kiyooka, Tohru Ohe
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 292:H2737-H2744
Pulmonary hypertension (PH) causes right ventricular (RV) hypertrophy and, according to the extent of pressure overload, eventual heart failure. We tested the hypothesis that the mechanical stress in PH-RV impairs the vasoreactivity of the RV coronar
Autor:
Yukihisa Hamaguchi, Koichi Furukawa, Daisuke Yamashita, Juichiro Shimizu, Takehiro Miyasaka, Yasushi Tatematsu, Tadayuki Uetani, Hiromi Misawa, Yuki Katanosaka, Toyoaki Murohara, Miyako Takaki, Tatsuaki Matsubara, Shinsuke Nakayama, Toshiaki Kato
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 292:H1181-H1186
Nuclear magnetic resonance (NMR) spectroscopy of the heart is normally carried out using whole heart preparations under coronary perfusion. In such preparations, either radical changes in ionic composition of the perfusate or applications of numerous