Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Jui-Hung Yen"'
Publikováno v:
Tzu-Chi Medical Journal, Vol 36, Iss 4, Pp 360-369 (2024)
A decrease in the levels of low-density lipoprotein receptors (LDLRs) leads to the accumulation of LDL cholesterol (LDL-C) in the bloodstream, resulting in hypercholesterolemia and atherosclerotic cardiovascular diseases. Increasing the expression le
Externí odkaz:
https://doaj.org/article/d9192fc35f1b4bb1bf28bf8e7eb63c93
Autor:
Jui-Hung Yen, Pei Ying Keak, Chia-Ling Wu, Hsuan-Jan Chen, Wan-Yun Gao, Je-Wen Liou, Yi-Ruei Chen, Liang-In Lin, Pei-Yi Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117395- (2024)
Core binding factor acute myeloid leukemia (CBF-AML) stands out as the most common type of adult AML, characterized by specific chromosomal rearrangements involving CBF genes, particularly t(8;21). Shikonin (SHK), a naphthoquinone phytochemical widel
Externí odkaz:
https://doaj.org/article/d37033c42ccd486e9456e0a502ee75c8
Publikováno v:
Tzu-Chi Medical Journal, Vol 36, Iss 3, Pp 231-239 (2024)
Chemokines are small, secreted cytokines crucial in the regulation of a variety of cell functions. The binding of chemokine C-X-C motif chemokine ligand 12 (CXCL12) (stromal cell-derived factor 1) to a G-protein-coupled receptor C-X-C chemokine recep
Externí odkaz:
https://doaj.org/article/9ce66f22d15d40f990b7f887d4fd3bee
Autor:
Wan-Yun Gao, Pei-Yi Chen, Hao-Jen Hsu, Je-Wen Liou, Chia-Ling Wu, Ming-Jiuan Wu, Jui-Hung Yen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116598- (2024)
Angiopoietin-like 3 (ANGPTL3) acts as an inhibitor of lipoprotein lipase (LPL), impeding the breakdown of triglyceride-rich lipoproteins (TGRLs) in circulation. Targeting ANGPTL3 is considered a novel strategy for improving dyslipidemia and atheroscl
Externí odkaz:
https://doaj.org/article/b957f1ab52b242d498b1c22617f10b61
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Bletilla species are endangered terrestrial orchids used in natural skin care formulas in Asia for a long history. In order to explore the bioactivity potential of Bletilla species as a cosmetic ingredient in a sustainable resourc
Externí odkaz:
https://doaj.org/article/e4875fef400c4fa4b3505a1a5f568b57
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Adipose tissue inflammation is considered as one of the major mechanisms underlying the pathogenesis of insulin resistance and complications in diabetes. Here, we aimed to study the effects of adipose-derived stromal cells on diab
Externí odkaz:
https://doaj.org/article/d1ab092c0e224d16929cc3c5324f9b92
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1575 (2023)
Background: 8-hydroxydaidzein (8-OHD) is a compound derived from daidzein, known for its anti-inflammatory and anti-proliferative properties in K562 human chronic myeloid leukemia (CML) cells. However, its effects on acute myeloid leukemia (AML) cell
Externí odkaz:
https://doaj.org/article/25c9352d975548988ac289bba4be09f8
Autor:
Pei-Rong Chang, Je-Wen Liou, Pei-Yi Chen, Wan-Yun Gao, Chia-Ling Wu, Ming-Jiuan Wu, Jui-Hung Yen
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2376 (2023)
The overactive hypothalamic–pituitary–adrenal (HPA) axis is believed to trigger the overproduction of corticosterone, leading to neurotoxicity in the brain. Fisetin is a flavonoid commonly found in fruits and vegetables. It has been suggested to
Externí odkaz:
https://doaj.org/article/83b4ce27d6704a77af93b35e3f562ad2
Publikováno v:
Tzu-Chi Medical Journal, Vol 34, Iss 2, Pp 139-147 (2022)
Coevolution occurs between viruses and their hosts. The hosts need to evolve means to eliminate pathogenic virus infections, and the viruses, for their own survival and multiplication, have to develop mechanisms to escape clearance by hosts. Hepatiti
Externí odkaz:
https://doaj.org/article/89f285d4c19748ceb55b52b9b214b374
Publikováno v:
Bioengineering, Vol 10, Iss 9, p 1004 (2023)
The structural analysis of proteins is a major domain of biomedical research. Such analysis requires resolved three-dimensional structures of proteins. Advancements in computer technology have led to progress in biomedical research. In silico predict
Externí odkaz:
https://doaj.org/article/33a12f5a50f14a1abd16311ca53fbf17