Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jui Yun Lu"'
Autor:
Hemanth R. Nelvagal, Samantha L. Eaton, Sophie H. Wang, Elizabeth M. Eultgen, Keigo Takahashi, Steven Q. Le, Rachel Nesbitt, Joshua T. Dearborn, Nicholas Siano, Ana C. Puhl, Patricia I. Dickson, Gerard Thompson, Fraser Murdoch, Paul M. Brennan, Mark Gray, Stephen N. Greenhalgh, Peter Tennant, Rachael Gregson, Eddie Clutton, James Nixon, Chris Proudfoot, Stefano Guido, Simon G. Lillico, C. Bruce A. Whitelaw, Jui-Yun Lu, Sandra L. Hofmann, Sean Ekins, Mark S. Sands, Thomas M. Wishart, Jonathan D. Cooper
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 20 (2022)
CLN1 disease, also called infantile neuronal ceroid lipofuscinosis (NCL) or infantile Batten disease, is a fatal neurodegenerative lysosomal storage disorder resulting from mutations in the CLN1 gene encoding the soluble lysosomal enzyme palmitoyl-pr
Externí odkaz:
https://doaj.org/article/fb7adb2cd6174d5a9c38555ece25def7
Autor:
Sandra L. Hofmann, John D. Minna, Ignacio I. Wistuba, Eugene P. Frenkel, Jaime Rodriguez-Canales, Hui Liu, Luc Girard, Jill E. Larsen, Ryan M. Carstens, Kenneth E. Huffman, Chunli Shao, Jui-Yun Lu, Hui Tian
Supplementary Figures S1-S5 and Supplementary Methods. Figure S1: Screening of a large number of NSCLC lines for sensitivity to siRNAs directed against 23 DHHC palmitoyltransferases. Figure S2: Membrane localization of DHHC5 in DHHC5 and DHHS mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a14431f6d2462aed52d13a6bfd01c6
https://doi.org/10.1158/1541-7786.22515022
https://doi.org/10.1158/1541-7786.22515022
Autor:
Sandra L. Hofmann, John D. Minna, Ignacio I. Wistuba, Eugene P. Frenkel, Jaime Rodriguez-Canales, Hui Liu, Luc Girard, Jill E. Larsen, Ryan M. Carstens, Kenneth E. Huffman, Chunli Shao, Jui-Yun Lu, Hui Tian
Tables S1-S3 Table S1. Non-small cell lung cancer cell lines used in the current study. Table S2. Clinicopathological characteristics for 194 primary patient samples (NSCLC). Table S3. siRNA used in screen (purchased from Qiagen) in 53 NSCLC lines an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f402e2febf59551fc67d9a7ab7f3995
https://doi.org/10.1158/1541-7786.22515019
https://doi.org/10.1158/1541-7786.22515019
Autor:
Jui-Yun Lu, Sandra L. Hofmann
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 7, Pp 1352-1357 (2006)
Much is now understood concerning the synthesis of prenylated and palmitoylated proteins, but what is known of their metabolic fate? This review details metabolic pathways for the lysosomal degradation of S-fatty acylated and prenylated proteins. Cen
Externí odkaz:
https://doaj.org/article/9669acde9ec74620a2c7a5aaee279303
Publikováno v:
eLife, Vol 2 (2013)
In fibroblasts, large Ca transients activate massive endocytosis (MEND) that involves membrane protein palmitoylation subsequent to mitochondrial permeability transition pore (PTP) openings. Here, we characterize this pathway in cardiac muscle. Myocy
Externí odkaz:
https://doaj.org/article/9ff487c1759e425a9fcbed3a88b83b6b
Autor:
Jui Yun Lu, Antonella Cecchettini, Filippo M. Santorelli, Ambra Del Grosso, Sandra L. Hofmann, Melissa Santi, Marco Cecchini, Marianna Galliani, Giovanni Signore, Lucia Angella
Publikováno v:
Bioconjugate chemistry (Online) 29 (2018): 2225–2231. doi:10.1021/acs.bioconjchem.8b00206
info:cnr-pdr/source/autori:Galliani M.; Santi M.; Del Grosso A.; Cecchettini A.; Santorelli F.M.; Hofmann S.L.; Lu J.-Y.; Angella L.; Cecchini M.; Signore G./titolo:Cross-Linked Enzyme Aggregates as Versatile Tool for Enzyme Delivery: Application to Polymeric Nanoparticles/doi:10.1021%2Facs.bioconjchem.8b00206/rivista:Bioconjugate chemistry (Online)/anno:2018/pagina_da:2225/pagina_a:2231/intervallo_pagine:2225–2231/volume:29
info:cnr-pdr/source/autori:Galliani M.; Santi M.; Del Grosso A.; Cecchettini A.; Santorelli F.M.; Hofmann S.L.; Lu J.-Y.; Angella L.; Cecchini M.; Signore G./titolo:Cross-Linked Enzyme Aggregates as Versatile Tool for Enzyme Delivery: Application to Polymeric Nanoparticles/doi:10.1021%2Facs.bioconjchem.8b00206/rivista:Bioconjugate chemistry (Online)/anno:2018/pagina_da:2225/pagina_a:2231/intervallo_pagine:2225–2231/volume:29
Polymeric nanoparticles (NPs) represent one of the most promising tools in nanomedicine and have been extensively studied for the delivery of water-insoluble drugs. However, the efficient loading of therapeutic enzymes and proteins in polymer-based n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8dd03f2d4128988f41c90175aedecd
http://hdl.handle.net/11568/926090
http://hdl.handle.net/11568/926090
Autor:
Jonathan D. Cooper, Sandra L. Hofmann, Shari G. Birnbaum, Jui Yun Lu, Hemanth R. Nelvagal, Lingling Wang
Publikováno v:
Molecular Genetics and Metabolism. 116:98-105
The neuronal ceroid lipofuscinoses (NCLs) are a group of related hereditary lysosomal storage disorders characterized by progressive loss of neurons in the central nervous system resulting in dementia, loss of motor skills, seizures and blindness. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10eda104dd7f6cc015eee9003e907439
https://doi.org/10.1016/j.ymgme.2015.05.005
https://doi.org/10.1016/j.ymgme.2015.05.005
Publikováno v:
Molecular Genetics and Metabolism. 99:374-378
Infantile neuronal ceroid lipofuscinosis (INCL, also known as Haltia-Santavuori disease) is a lysosomal storage disorder of infants and children characterized by blindness, seizures and a progressive neurodegenerative course. Recent clinical trials h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488c501d15b036ada54c450c9abfbd86
https://doi.org/10.1016/j.ymgme.2009.12.002
https://doi.org/10.1016/j.ymgme.2009.12.002
Autor:
Charles Shyng, Mark S. Sands, Joshua T. Dearborn, Jui Yun Lu, Jonah Thornton, Subramania Ramachandran, Sandra L. Hofmann
Infantile neuronal ceroid lipofuscinosis (INCL, Infantile Batten disease) is an invariably fatal neurodegenerative pediatric disorder caused by an inherited mutation in the PPT1 gene. Patients with INCL lack the lysosomal enzyme palmitoyl protein thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8833cc734d68fbf2f6a05af6358602a
https://europepmc.org/articles/PMC4755911/
https://europepmc.org/articles/PMC4755911/
Autor:
Jui-Yun Lu, 呂瑞雲
104
The cosmetics manufacturing know-how of Taiwan was originated from Japan. Due to the scarcity of supplies after the World War II, cosmetics were categorized as luxury products by the government and import was prohibited. After the ban on lux
The cosmetics manufacturing know-how of Taiwan was originated from Japan. Due to the scarcity of supplies after the World War II, cosmetics were categorized as luxury products by the government and import was prohibited. After the ban on lux
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/59547317608633144749