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Autor:
Juthamas Sukbuntherng, Susan O'Brien, David Loury, John C. Byrd, Peter Hellemans, Jan de Jong, Danelle F. James, Donna Skee, Joseph Murphy, Vijay Chauhan, Erik Mannaert, Juhui Jiao
Publikováno v:
Cancer chemotherapy and pharmacology, vol 75, iss 5
Cancer Chemotherapy and Pharmacology
Cancer Chemotherapy and Pharmacology
Purpose To assess ibrutinib pharmacokinetics under fasted and fed conditions, impact of food-intake timing, and the safety and tolerability. Methods Three studies were analyzed. Study 1 was a randomized, open-label, single-dose, four-way crossover st