Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Juho, Alaviuhkola"'
Autor:
Sudarshan, Murthy, Maria Giulia, Nizi, Mirko M, Maksimainen, Serena, Massari, Juho, Alaviuhkola, Barbara E, Lippok, Chiara, Vagaggini, Sven T, Sowa, Albert, Galera-Prat, Yashwanth, Ashok, Harikanth, Venkannagari, Renata, Prunskaite-Hyyryläinen, Elena, Dreassi, Bernhard, Lüscher, Patricia, Korn, Oriana, Tabarrini, Lari, Lehtiö
Publikováno v:
Journal of medicinal chemistry.
We report [1,2,4]triazolo[3,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7842b39c06010b4651f7dd439c1106f
https://pubmed.ncbi.nlm.nih.gov/36598465
https://pubmed.ncbi.nlm.nih.gov/36598465
Autor:
Sudarshan Murthy, Maria Giulia Nizi, Mirko M. Maksimainen, Serena Massari, Juho Alaviuhkola, Barbara E. Lippok, Chiara Vagaggini, Sven T. Sowa, Albert Galera-Prat, Yashwanth Ashok, Harikanth Venkannagari, Renata Prunskaite-Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, Lari Lehtiö
Publikováno v:
Journal of medicinal chemistry 66(2), 1301-1320 (2023). doi:10.1021/acs.jmedchem.2c01460
Journal of medicinal chemistry 66(2), 1301-1320 (2023). doi:10.1021/acs.jmedchem.2c01460
Published by American Chemical Society, Washington, DC
Published by American Chemical Society, Washington, DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02c78b88c3e04c15acc5405940609a1
http://urn.fi/urn:nbn:fi-fe2023032232837
http://urn.fi/urn:nbn:fi-fe2023032232837
Publikováno v:
Protein Engineering, Design and Selection. 35
Human mono-ADP-ribosylating PARP enzymes have been linked to several clinically relevant processes and many of these PARPs have been suggested as potential drug targets. Despite recent advances in the field, efforts to discover such compounds have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6860f719496b152e5ce157a159c1cdd5
https://doi.org/10.1093/protein/gzac006
https://doi.org/10.1093/protein/gzac006
Autor:
Maria Giulia Nizi, Mirko M. Maksimainen, Sudarshan Murthy, Serena Massari, Juho Alaviuhkola, Barbara E. Lippok, Sven T. Sowa, Albert Galera-Prat, Renata Prunskaite-Hyyryläinen, Bernhard Lüscher, Patricia Korn, Lari Lehtiö, Oriana Tabarrini
Publikováno v:
European journal of medicinal chemistry. 237
While human poly-ADP-ribose chain generating poly-ARTs, PARP1 and 2 and TNKS1 and 2, have been widely characterized, less is known on the pathophysiological roles of the mono-ADP-ribosylating mono-ARTs, partly due to the lack of selective inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05c6c6e0d4bd59ece054ca76697b142
https://pubmed.ncbi.nlm.nih.gov/35500474
https://pubmed.ncbi.nlm.nih.gov/35500474