Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Juha-Matti Lehtola"'
Autor:
Laura M. Rantanen, Maina Bitar, Riikka Lampinen, Romal Stewart, Hazel Quek, Lotta E. Oikari, Carla Cunί-Lόpez, Ratneswary Sutharsan, Gayathri Thillaiyampalam, Jamila Iqbal, Daniel Russell, Elina Penttilä, Heikki Löppönen, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Anne M. Koivisto, Larisa M. Haupt, Alan Mackay-Sim, Alexandre S. Cristino, Katja M. Kanninen, Anthony R. White
Publikováno v:
Cells, Vol 11, Iss 20, p 3258 (2022)
An early symptom of Alzheimer’s disease (AD) is an impaired sense of smell, for which the molecular basis remains elusive. Here, we generated human olfactory neurosphere-derived (ONS) cells from people with AD and mild cognitive impairment (MCI), a
Externí odkaz:
https://doaj.org/article/dca05e7e61d14b3aa34487459c0f0668
Autor:
Riikka Lampinen, Veronika Górová, Simone Avesani, Jeffrey R. Liddell, Elina Penttilä, Táňa Závodná, Zdeněk Krejčík, Juha-Matti Lehtola, Toni Saari, Juho Kalapudas, Sanna Hannonen, Heikki Löppönen, Jan Topinka, Anne M. Koivisto, Anthony R. White, Rosalba Giugno, Katja M. Kanninen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4123 (2022)
Olfactory function, orchestrated by the cells of the olfactory mucosa at the rooftop of the nasal cavity, is disturbed early in the pathogenesis of Alzheimer’s disease (AD). Biometals including zinc and calcium are known to be important for sense o
Externí odkaz:
https://doaj.org/article/24e6ca5098954547b4ce989fae2cf1f7
Autor:
Riikka Lampinen, Mohammad Feroze Fazaludeen, Simone Avesani, Tiit Örd, Elina Penttilä, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Liudmila Saveleva, Emma Kaartinen, Francisco Fernández Acosta, Marcela Cruz-Haces, Heikki Löppönen, Alan Mackay-Sim, Minna U. Kaikkonen, Anne M. Koivisto, Tarja Malm, Anthony R. White, Rosalba Giugno, Sweelin Chew, Katja M. Kanninen
Publikováno v:
Cells, Vol 11, Iss 4, p 676 (2022)
Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity. Olfactory dysfunction manifests early in several neurodegenerative disorders including Alzheimer’s disease, however, disease-related alterations to the olfactor
Externí odkaz:
https://doaj.org/article/f37964f4ad0445378ce4d9197ff96e19
Autor:
Laura M. Rantanen, Maina Bitar, Riikka Lampinen, Romal Stewart, Hazel Quek, Lotta E. Oikari, Carla Cunί-Lόpez, Ratneswary Sutharsan, Gayathri Thillaiyampalam, Jamila Iqbal, Daniel Russell, Elina Penttilä, Heikki Löppönen, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Anne M Koivisto, Larisa M. Haupt, Alan Mackay-Sim, Alexandre S. Cristino, Katja M. Kanninen, Anthony R. White
An early symptom of Alzheimer’s disease (AD) is an impaired sense of smell, for which the molecular basis remains elusive. Here, we generated human olfactory neurosphere-derived (ONS) cells from people with AD and mild cognitive impairment (MCI), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::354e428e616eaf06921774d3cad236a1
https://doi.org/10.1101/2022.08.22.504884
https://doi.org/10.1101/2022.08.22.504884
Autor:
Sanna, Hannonen, Sami, Andberg, Virve, Kärkkäinen, Minna, Rusanen, Juha-Matti, Lehtola, Toni, Saari, Ville, Korhonen, Laura, Hokkanen, Merja, Hallikainen, Tuomo, Hänninen, Ville, Leinonen, Kai, Kaarniranta, Roman, Bednarik, Anne M, Koivisto
Publikováno v:
Journal of Alzheimer's disease : JAD. 88(2)
Wide-ranging functional defects in eye movements have been reported in Alzheimer's disease (AD) dementia. The detection of abnormal eye movements and reading problems may identify persons at risk of AD when clear clinical symptoms are lacking.To exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ea336d8d9dc41e8aa1c875d4af77fdf
https://pubmed.ncbi.nlm.nih.gov/35662117
https://pubmed.ncbi.nlm.nih.gov/35662117
Autor:
Kanninen, Riikka Lampinen, Veronika Górová, Simone Avesani, Jeffrey R. Liddell, Elina Penttilä, Táňa Závodná, Zdeněk Krejčík, Juha-Matti Lehtola, Toni Saari, Juho Kalapudas, Sanna Hannonen, Heikki Löppönen, Jan Topinka, Anne M. Koivisto, Anthony R. White, Rosalba Giugno, Katja M.
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 8; Pages: 4123
Olfactory function, orchestrated by the cells of the olfactory mucosa at the rooftop of the nasal cavity, is disturbed early in the pathogenesis of Alzheimer’s disease (AD). Biometals including zinc and calcium are known to be important for sense o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::9d087db801b9acc97fab18e2a9ea0257
Autor:
Juha-Matti Lehtola, Virve Kärkkäinen, Sami Andberg, Sanna Hannonen, Minna Rusanen, Toni Saari, Ville Korhonen, Laura Hokkanen, Merja Hallikainen, Tuomo Hänninen, Kai Kaarniranta, Roman Bednarik, Ville Leinonen, Anne M. Koivisto
Publikováno v:
Alzheimer disease and associated disorders. 36(4)
Publisher Copyright: © 2022 Lippincott Williams and Wilkins. All rights reserved. Background: Functional defects in eye movements and reduced reading speed in neurodegenerative diseases represent a potential new biomarker to support clinical diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fd4f1382d911ad5eae7055059ad27d
https://pubmed.ncbi.nlm.nih.gov/36219131
https://pubmed.ncbi.nlm.nih.gov/36219131
Autor:
Kanninen, Riikka Lampinen, Mohammad Feroze Fazaludeen, Simone Avesani, Tiit Örd, Elina Penttilä, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Liudmila Saveleva, Emma Kaartinen, Francisco Fernández Acosta, Marcela Cruz-Haces, Heikki Löppönen, Alan Mackay-Sim, Minna U. Kaikkonen, Anne M. Koivisto, Tarja Malm, Anthony R. White, Rosalba Giugno, Sweelin Chew, Katja M.
Publikováno v:
Cells; Volume 11; Issue 4; Pages: 676
Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity. Olfactory dysfunction manifests early in several neurodegenerative disorders including Alzheimer’s disease, however, disease-related alterations to the olfactor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::ba4ace181fbb840c4282f6ddddc75e5c
Autor:
Kasper, Katisko, Antti, Cajanus, Nadine, Huber, Olli, Jääskeläinen, Tarja, Kokkola, Virve, Kärkkäinen, Hannah, Rostalski, Paivi, Hartikainen, Anne M, Koivisto, Sanna, Hannonen, Juha-Matti, Lehtola, Ville E, Korhonen, Seppo, Helisalmi, Heli, Koivumaa-Honkanen, Sanna-Kaisa, Herukka, Anne M, Remes, Eino, Solje, Annakaisa, Haapasalo
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry. 92(12)
Frontotemporal lobar degeneration (FTLD) and primary psychiatric disorders (PPD) are characterised by overlapping clinical features but different aetiologies. Here, we assessed for the first time the potential of blood glial fibrillar acidic protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c1a58ce046b1abe45e49e4e56452cae
https://pubmed.ncbi.nlm.nih.gov/34479952
https://pubmed.ncbi.nlm.nih.gov/34479952
Autor:
Rosalba Giugno, Katja M. Kanninen, Anthony R. White, Löppönen H, Avesani S, Sweelin Chew, Penttilä E, Riikka Lampinen, Alan Mackay-Sim, Cruz-Haces M, Hannonen S, Minna Kaikkonen-Maatta, Acosta Ff, Koivisto Am, Juha-Matti Lehtola, Kaartinen E, Toni Saari, Tiit Örd, Mohammad Feroze Fazaludeen, Tarja Malm, Liudmila Saveleva
Olfactory dysfunction manifests early in several neurodegenerative disorders. Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity. However, it is unclear how this tissue reflects key neurodegenerative features in Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddec111dd27b6db8d687465959feeff2
https://doi.org/10.1101/2020.11.24.395947
https://doi.org/10.1101/2020.11.24.395947