Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Juha-Matti Hyttinen"'
Autor:
Juhani Jänne, Veli-Pekka Korhonen, Mikko Uusi-Oukari, A Västi, Olli A. Jänne, Juha-Matti Hyttinen, Leena Alhonen
Publikováno v:
Transgenic Research. 6:75-84
The generation is reported of transgenic mice expressing human granulocyte-macrophage colony-stimulating factor (GM-CSF) or human erythropoietin (EPO) under the control of bovine alpha s1-casein regulatory sequences. GM-CSF expression was specific to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14245c9df7397a9f6c8e9b349198d121
https://doi.org/10.1023/a:1018461201385
https://doi.org/10.1023/a:1018461201385
Publikováno v:
Theriogenology. 42:433-443
The effects of gene injection-related handling on the subsequent development of in vitro-produced bovine oocytes were studied. In Experiment 1, centrifuged oocytes were stored in an injection chamber for 30 min on a warm (+39 degrees C) stage at 18,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8ac52673fdd45c0dbe62d0f4f6b99a
https://doi.org/10.1016/0093-691x(94)90681-8
https://doi.org/10.1016/0093-691x(94)90681-8
Autor:
Pia Leppänen, Maria Halmekytö, Juha-Matti Hyttinen, Leena Alhonen, Juhani Jänne, Riitta Sinervirta
Publikováno v:
Biochemical Journal. 292:927-932
We have studied the regulation of the expression of ornithine decarboxylase with the aid of transgenic mice harbouring either functional human ornithine decarboxylase genes or the mouse ornithine decarboxylase promoter-driven chloramphenicol acetyltr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413ee6fd9df2f7819c8765d5bd610ac0
https://doi.org/10.1042/bj2920927
https://doi.org/10.1042/bj2920927
Autor:
Sanna Myöhänen, K Syrjänen, S Syrjänen, Maria Halmekytö, Jarmo Wahlfors, Riitta Sinervirta, H M Voipio, Juha-Matti Hyttinen, Leena Alhonen, M Utriainen
Publikováno v:
Journal of Biological Chemistry. 266:19746-19751
We have generated transgenic mice carrying human ornithine decarboxylase gene. Two different transgene constructs were used: (i) a 5'-truncated human ornithine decarboxylase gene and (ii) an intact human ornithine decarboxylase gene. Transgenic mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32e0260c3502285da1b9c942d0232ed5
https://doi.org/10.1016/s0021-9258(18)55055-9
https://doi.org/10.1016/s0021-9258(18)55055-9
Autor:
Juhani Jänne, Juha-Matti Hyttinen, Richard Villems, Mart Saarma, Meelis Kolmer, Leena Alhonen, Tônis Örd
Publikováno v:
Genomics. 10:496-498
Chymosin is an extremely specific aspartatic protease responsible for milk coagulation. Chymosin is expressed in a number of mammalian offspring, yet its presence in the gastric tissue of human infants remains a matter of controversy. In any event, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f34cc7d408d6bd93d8c52c086dc9dc6
https://doi.org/10.1016/0888-7543(91)90340-k
https://doi.org/10.1016/0888-7543(91)90340-k
Publikováno v:
Journal of biotechnology. 61(3)
To study the expression of the bovine β-lactoglobulin (BLG) gene we isolated the BLG gene from a genomic library and introduced it into murine germline. Bovine BLG gene including 2.8 kbp of 5′ and 1.9 kbp of 3′ flanking region was expressed effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b32dde331d341a319e714156ca7d462
https://pubmed.ncbi.nlm.nih.gov/9684337
https://pubmed.ncbi.nlm.nih.gov/9684337
Publikováno v:
Mammary Gland Transgenesis ISBN: 9783662033746
Mammary Gland Transgenesis
Mammary Gland Transgenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8f3ef325e29e0c2878f2886bcfbce6f
https://doi.org/10.1007/978-3-662-03372-2_10
https://doi.org/10.1007/978-3-662-03372-2_10
Publikováno v:
Molecular reproduction and development. 43(2)
We have developed a simple digestion-polymerase chain reaction (PCR) assay for a simultaneous transgene detection and sexing of pronucleus-injected bovine preimplantation embryos. Bovine embryos were microinjected with dam-methylated gene construct a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308b77cf1ef5d1cf0d05145dee7f111d
https://pubmed.ncbi.nlm.nih.gov/8824912
https://pubmed.ncbi.nlm.nih.gov/8824912
Autor:
Juhani Jänne, Juha-Matti Hyttinen, Teija Peura, Minna Tolvanen, Leena Alhonen, Rlitta Sinervirta, Maria Halmekytö
Publikováno v:
The International journal of biochemistry. 26(7)
1. Although many human therapeutic proteins are currently produced in microbial fermentors using recombinant DNA techniques, it is obvious that microbial processing is not suitable for a large number of bioactive proteins owing to the inability of ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd853401eb8987d94f87baccc5ff84b6
https://pubmed.ncbi.nlm.nih.gov/8063010
https://pubmed.ncbi.nlm.nih.gov/8063010