Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Juha-Matti Alakoskela"'
Autor:
Tuuli A. Hakala, Laura K. Zschaechner, Risto T. Vänskä, Teemu A. Nurminen, Melissa Wardale, Jonathan Morina, Zhanna A. Boeva, Reeta Saukkonen, Juha-Matti Alakoskela, Kim Pettersson-Fernholm, Edward Hæggström, Johan Bobacka, Alejandro García Pérez
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The benefits of continuous glucose monitoring (CGM) in diabetes management are extensively documented. Yet, the broader adoption of CGM systems is limited by their cost and invasiveness. Current CGM devices, requiring implantation or the use
Externí odkaz:
https://doaj.org/article/6136219f5e3444d9a174ad0f7e7fa767
Autor:
Tuuli A. Hakala, Alejandro García Pérez, Melissa Wardale, Ida A. Ruuth, Risto T. Vänskä, Teemu A. Nurminen, Emily Kemp, Zhanna A. Boeva, Juha-Matti Alakoskela, Kim Pettersson-Fernholm, Edward Hæggström, Johan Bobacka
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Out of 463 million people currently with diabetes, 232 million remain undiagnosed. Diabetes is a threat to human health, which could be mitigated via continuous self-monitoring of glucose. In addition to blood, interstitial fluid is consider
Externí odkaz:
https://doaj.org/article/9a36cbe95de24056ade44d9c13124287
Autor:
Alice C. N. Brown, Stephane Oddos, Ian M. Dobbie, Juha-Matti Alakoskela, Richard M. Parton, Philipp Eissmann, Mark A. A. Neil, Christopher Dunsby, Paul M. W. French, Ilan Davis, Daniel M. Davis
Publikováno v:
PLoS Biology, Vol 10, Iss 8 (2012)
Externí odkaz:
https://doaj.org/article/217077cea1f44f1ab4c2c0c7d74b8c48
Autor:
Alice C N Brown, Stephane Oddos, Ian M Dobbie, Juha-Matti Alakoskela, Richard M Parton, Philipp Eissmann, Mark A A Neil, Christopher Dunsby, Paul M W French, Ilan Davis, Daniel M Davis
Publikováno v:
PLoS Biology, Vol 9, Iss 9, p e1001152 (2011)
Natural Killer (NK) cells are innate immune cells that secrete lytic granules to directly kill virus-infected or transformed cells across an immune synapse. However, a major gap in understanding this process is in establishing how lytic granules pass
Externí odkaz:
https://doaj.org/article/c5fbcad5246744319db3103246e810fc
Autor:
Alejandro Garcia Perez, Emily Kemp, Tuuli A. Hakala, Melissa Wardale, Kim Pettersson-Fernholm, Ida A. Ruuth, Zhanna A. Boeva, Teemu A. Nurminen, Johan Bobacka, Edward Hæggström, Risto T. Vänskä, Juha Matti Alakoskela
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Out of 463 million people currently with diabetes, 232 million remain undiagnosed. Diabetes is a threat to human health, which could be mitigated via continuous self-monitoring of glucose. In addition to blood, interstitial fluid is considered to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499291d1c4aeadbc668abab66b427923
http://europepmc.org/articles/PMC8027418
http://europepmc.org/articles/PMC8027418
Natural killer (NK) cells secrete lytic granules to directly kill virus-infected or transformed cells and secrete cytokines to communicate with other cells. Three-dimensional super-resolved images of F-actin, lytic granules, and IFN-γ in primary hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d66a5a35a0ec7d958e105660a986af
https://ora.ox.ac.uk/objects/uuid:3208e9e8-2feb-4b8d-85e1-e059b7d7297e
https://ora.ox.ac.uk/objects/uuid:3208e9e8-2feb-4b8d-85e1-e059b7d7297e
Publikováno v:
Langmuir. 26:4892-4900
1,2-Dimyristoyl-sn-glycero-3-phospho-rac-glycerol (DMPG) at low salt concentrations has a complex endotherm with at least four components and extending over the span of 20 degrees. During this ongoing melting, the solution becomes viscous and scatter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0a09ca9acab67e6413da08083e6804
https://doi.org/10.1021/la100411p
https://doi.org/10.1021/la100411p
Autor:
Mikko J. Parry, Juha-Matti Alakoskela, Himanshu Khandelia, Subramanian Arun Kumar, Ajay K. Mahalka, Paavo K.J. Kinnunen, Marja Jäättelä
Publikováno v:
Journal of the American Chemical Society. 130:12953-12960
Siramesine (SRM) is a sigma-2 receptor agonist which has been recently shown to inhibit growth of cancer cells. Fluorescence spectroscopy experiments revealed two distinct binding sites for this drug in phospholipid membranes. More specifically, acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dcd818a0208aca820bf403d1a6931ff
https://doi.org/10.1021/ja800516w
https://doi.org/10.1021/ja800516w
Publikováno v:
Journal of Medicinal Chemistry. 51:1842-1848
Phospholipidosis, the accumulation of phospholipids in cells, is a relatively frequent side effect of cationic amphiphilic drugs. In response to the industry need, several methods have been recently published for the prediction of the phospholipidosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf83c566f10dc9b1c3edd68c3cecaa1
https://doi.org/10.1021/jm7013953
https://doi.org/10.1021/jm7013953
Publikováno v:
Journal of Fluorescence. 17:97-103
A novel method for the quantitative assessment of the membrane partitioning of a ligand from the aqueous phase is described, demonstrated here with the thoroughly studied antipsychotic chlorpromazine (CPZ). More specifically, collisional quenching of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b910664b0b45514a905cc57e4e81da
https://doi.org/10.1007/s10895-006-0138-0
https://doi.org/10.1007/s10895-006-0138-0