Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Juha S. Tapanainen"'
Autor:
Laura Danti, Karolina Lundin, Kirsi Sepponen, Dawit A. Yohannes, Juha Kere, Timo Tuuri, Juha S. Tapanainen
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract The nuclear receptor subfamily 5 group A member 1 (NR5A1), encoding steroidogenic factor 1 (SF-1), has been identified as a critical factor in gonadal development in animal studies. A previous study of ours suggested that upregulation of NR5
Externí odkaz:
https://doaj.org/article/a031d67777244d8794bf7342530aed10
Autor:
Kaisu Luiro, Anna-Maaria Auvinen, Juha Auvinen, Jari Jokelainen, Ilkka Järvelä, Mikael Knip, Juha S. Tapanainen
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectiveTo study the predictive value of autoantibodies for type 1 (T1DM) and type 2 (T2DM) diabetes morbidity after gestational diabetes (GDM) in a 23-year follow-up study.DesignProspective population-based cohort study.MethodsWe studied 391 women
Externí odkaz:
https://doaj.org/article/b5345dee32504b79a324cfc6be937ed5
Autor:
Maria-Elina Mosorin, Terhi Piltonen, Anni S. Rantala, Marika Kangasniemi, Elisa Korhonen, Risto Bloigu, Juha S. Tapanainen, Laure Morin-Papunen
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 8, p 2827 (2023)
This clinical trial aims to compare hormonal and metabolic changes after a 9-week continuous use of oral or vaginal combined hormonal contraceptives (CHCs) in women with polycystic ovary syndrome (PCOS). We recruited 24 women with PCOS and randomized
Externí odkaz:
https://doaj.org/article/5b3ccd7f071149028461757a2498dda4
Autor:
Sanna Vuoristo, Shruti Bhagat, Christel Hydén-Granskog, Masahito Yoshihara, Lisa Gawriyski, Eeva-Mari Jouhilahti, Vipin Ranga, Mahlet Tamirat, Mikko Huhtala, Ida Kirjanov, Sonja Nykänen, Kaarel Krjutškov, Anastassius Damdimopoulos, Jere Weltner, Kosuke Hashimoto, Gaëlle Recher, Sini Ezer, Priit Paluoja, Pauliina Paloviita, Yujiro Takegami, Ai Kanemaru, Karolina Lundin, Tomi T. Airenne, Timo Otonkoski, Juha S. Tapanainen, Hideya Kawaji, Yasuhiro Murakawa, Thomas R. Bürglin, Markku Varjosalo, Mark S. Johnson, Timo Tuuri, Shintaro Katayama, Juha Kere
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104137- (2022)
Summary: Double homeobox 4 (DUX4) is expressed at the early pre-implantation stage in human embryos. Here we show that induced human DUX4 expression substantially alters the chromatin accessibility of non-coding DNA and activates thousands of newly i
Externí odkaz:
https://doaj.org/article/e20d78e8cdab451083fb4b3f94c08b7f
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background The length of interval between successive childbirths (birth interval) might influence the incidence of breast cancer, either by stimulating or by inhibiting the factors that are responsible for the initiation of breast cancer or
Externí odkaz:
https://doaj.org/article/2cecf81e4272435b9130661040343b85
Autor:
Martin P. Reichhardt, Karolina Lundin, A. Inkeri Lokki, Gaëlle Recher, Sanna Vuoristo, Shintaro Katayama, Juha S. Tapanainen, Juha Kere, Seppo Meri, Timo Tuuri
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
It is essential for early human life that mucosal immunological responses to developing embryos are tightly regulated. An imbalance of the complement system is a common feature of pregnancy complications. We hereby present the first full analysis of
Externí odkaz:
https://doaj.org/article/ca24da546e214717b90722733561c7cc
Autor:
Jan Roar Mellembakken, Azita Mahmoudan, Lars Mørkrid, Inger Sundström-Poromaa, Laure Morin-Papunen, Juha S Tapanainen, Terhi T Piltonen, Angelica Lindén Hirschberg, Elisabet Stener-Victorin, Eszter Vanky, Pernille Ravn, Richard Christian Jensen, Marianne Skovsager Andersen, Dorte Glintborg
Publikováno v:
Endocrine Connections, Vol 10, Iss 2, Pp 154-163 (2021)
Objective: Obesity is considered to be the strongest predictive factor for cardio-metabolic risk in women with polycystic ovary syndrome (PCOS). The aim of the study was to compare blood pressure (BP) in normal weight women with PCOS and controls mat
Externí odkaz:
https://doaj.org/article/ad6f63f4f6c04314a9b6d6839c04ce53
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Objectives Altered intestinal permeability and gut barrier dysfunction have been suggested to play a role in the pathogenetic mechanism of polycystic ovary syndrome (PCOS), the most common endocrine and metabolic condition in reproductive-aged women.
Externí odkaz:
https://doaj.org/article/aaa5ea193b5f4112a2281df19152c647
Autor:
Shilpa Lingaiah, Laure Morin-Papunen, Terhi Piltonen, Inger Sundström-Poromaa, Elisabet Stener-Victorin, Juha S Tapanainen
Publikováno v:
Endocrine Connections, Vol 8, Iss 6, Pp 709-717 (2019)
Objective: Serum levels of retinol-binding protein 4 (RBP4), an adipokine thought to affect systemic insulin sensitivity, were compared between women with polycystic ovary syndrome (PCOS) and non-PCOS controls to evaluate the association of RBP4 with
Externí odkaz:
https://doaj.org/article/636b77a631a14dcaa63dfb4ed84433a5
Autor:
Terhi T Piltonen, Maria Ruokojärvi, Helle Karro, Linda Kujanpää, Laure Morin-Papunen, Juha S Tapanainen, Elisabet Stener-Victorin, Inger Sundrström-Poromaa, Angelica L Hirschberg, Pernille Ravn, Dorte Glintborg, Jan Roar Mellembakken, Thora Steingrimsdottir, Melanie Gibson-Helm, Eszter Vanky, Marianne Andersen, Riikka K Arffman, Helena Teede, Kobra Falah-Hassani
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226074 (2019)
OBJECTIVE:To date, little is known about differences in the knowledge, diagnosis making and treatment strategies of health care providers regarding polycystic ovary syndrome (PCOS) across different disciplines in countries with similar health care sy
Externí odkaz:
https://doaj.org/article/e5f90cb807f74bee830ca3205308170a