Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Juha K Rantala"'
Autor:
Andrä Brunner, Aldwin Suryo Rahmanto, Henrik Johansson, Marcela Franco, Johanna Viiliäinen, Mohiuddin Gazi, Oliver Frings, Erik Fredlund, Charles Spruck, Janne Lehtiö, Juha K Rantala, Lars-Gunnar Larsson, Olle Sangfelt
Publikováno v:
eLife, Vol 9 (2020)
Inhibition of WEE1 kinase by AZD1775 has shown promising results in clinical cancer trials, but markers predicting AZD1775 response are lacking. Here we analysed AZD1775 response in a panel of human breast cancer (BC) cell lines by global proteome/tr
Externí odkaz:
https://doaj.org/article/c498116f3f834b90a997e94962d531e9
Autor:
Noora Lehtinen, Janne Suhonen, Kiesha Rice, Eetu Välimäki, Mervi Toriseva, Johannes Routila, Perttu Halme, Melissa Rahi, Heikki Irjala, Ilmo Leivo, Markku Kallajoki, Matthias Nees, Teijo Kuopio, Sami Ventelä, Juha K. Rantala
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101935- (2024)
Malignant tumors derived from the epithelium lining the nasal cavity region are termed sinonasal cancers, a highly heterogeneous group of rare tumors accounting for 3 – 5 % of all head and neck cancers. Progress with next-generation molecular profi
Externí odkaz:
https://doaj.org/article/1043b19b0c8148dc8cfad7e1e4daf8d5
Autor:
Rami Mäkelä, Antti Arjonen, Aldwin Suryo Rahmanto, Ville Härmä, Janne Lehtiö, Teijo Kuopio, Thomas Helleday, Olle Sangfelt, Juha Kononen, Juha K. Rantala
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 9, Pp 390-398 (2020)
Epithelial–myoepithelial carcinoma (EMC) is a rare subtype of salivary gland neoplasms. Since the initial description of the cancer, just over 300 cases have been reported. EMCs occupy a biphasic cellular differentiation-state defined by the consti
Externí odkaz:
https://doaj.org/article/b2d81484fc1741c8bc0de9e647a7ca62
Autor:
Rami Mäkelä, Antti Arjonen, Ville Härmä, Nina Rintanen, Lauri Paasonen, Tobias Paprotka, Kerstin Rönsch, Teijo Kuopio, Juha Kononen, Juha K. Rantala
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Ex vivo drug screening refers to the out-of-body assessment of drug efficacy in patient derived vital tumor cells. The purpose of these methods is to enable functional testing of patient specific efficacy of anti-cancer therapeuti
Externí odkaz:
https://doaj.org/article/57759f08eeff444d9a1a852ab997f3b4
Autor:
Noora Nykänen, Rami Mäkelä, Antti Arjonen, Ville Härmä, Laura Lewandowski, Eileen Snowden, Rainer Blaesius, Ismo Jantunen, Teijo Kuopio, Juha Kononen, Juha K. Rantala
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The purpose of ex vivo drug screening in the context of precision oncology is to serve as a functional diagnostic method for therapy efficacy modeling directly on patient-derived tumor cells. Here, we report a case study using integrated multiomics e
Externí odkaz:
https://doaj.org/article/64c466555b9440d99ca2297d9bc90351
Autor:
Juha K. Rantala, Antti Arjonen, Heikki Hakkarainen, Juha Kononen, Maija Hollmén, Rami Mäkelä, Reetta Virtakoivu, Teijo Kuopio, Ville Härmä
Publikováno v:
Clinical Oncology and Research. :1-8
Krukenberg tumor (KT) is a rare subtype of ovarian neoplasms that manifests as secondary ovarian cancer. Most frequently, KTs originate from a primary in the gastrointestinal tract and account for 30 to 40% of all secondary ovarian cancers. A key his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cf36513cf46092e9029000ee4089a42
https://doi.org/10.31487/j.cor.2020.07.01
https://doi.org/10.31487/j.cor.2020.07.01
Autor:
Lina Cekaite, Juha K. Rantala, Jarle Bruun, Marianne Guriby, Trude H. Ågesen, Stine A. Danielsen, Guro E. Lind, Arild Nesbakken, Olli Kallioniemi, Ragnhild A. Lothe, Rolf I. Skotheim
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 9, Pp 868-879 (2012)
Several microRNAs (miRNAs) are known to be deregulated in colon cancer, but the mechanisms behind their potential involvement on proliferation and tumor cell survival are unclear. The present study aimed to identify miRNAs with functional implication
Externí odkaz:
https://doaj.org/article/fec7c093a2f84e6cafaa0c5f14d3aa5b
Autor:
Juha K. Rantala, Henrik Edgren, Laura Lehtinen, Maija Wolf, Kristine Kleivi, Hans Kristian Moen Vollan, Anna-Riina Aaltola, Petra Laasola, Sami Kilpinen, Petri Saviranta, Kristiina Iljin, Olli Kallioniemi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 11, Pp 877-888 (2010)
Aneuploidy is among the most obvious differences between normal and cancer cells. However, mechanisms contributing to development and maintenance of aneuploid cell growth are diverse and incompletely understood. Functional genomics analyses have show
Externí odkaz:
https://doaj.org/article/6f6d90d7e02a40de9e1ca47441b9ead5
Cisplatin overcomes radiotherapy resistance in OCT4-expressing head and neck squamous cell carcinoma
Autor:
Johannes Routila, Xi Qiao, Jere Weltner, Juha K Rantala, Timo Carpén, Jaana Hagström, Antti Mäkitie, Ilmo Leivo, Miia Ruuskanen, Jenni Söderlund, Marjut Rintala, Sakari Hietanen, Heikki Irjala, Heikki Minn, Jukka Westermarck, Sami Ventelä
Publikováno v:
Oral Oncology. 127:105772
Objectives: Cisplatin is combined with radiotherapy for advanced head and neck squamous cell carcinoma (HNSCC). While providing a beneficial effect on survival, it also causes side effects and thus is an important target when considering treatment de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a8dc3c6c4ceb07b436529e322dc4d6
https://doi.org/10.1016/j.oraloncology.2022.105772
https://doi.org/10.1016/j.oraloncology.2022.105772
Autor:
Khalid, Saeed, Päivi, Östling, Mari, Björkman, Tuomas, Mirtti, Kalle, Alanen, Tiina, Vesterinen, Anna, Sankila, Johan, Lundin, Mikael, Lundin, Antti, Rannikko, Stig, Nordling, John-Patrick, Mpindi, Pekka, Kohonen, Kristiina, Iljin, Olli, Kallioniemi, Juha K, Rantala
Publikováno v:
International journal of cancer. 136(11)
Hormonal therapies targeting androgen receptor (AR) are effective in prostate cancer (PCa), but often the cancers progress to fatal castrate-resistant disease. Improved understanding of the cellular events during androgen deprivation would help to id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e70c57dbf8baef21ec6878ea88ee66a
https://pubmed.ncbi.nlm.nih.gov/25359680
https://pubmed.ncbi.nlm.nih.gov/25359680