Zobrazeno 1 - 10
of 98 382
pro vyhledávání: '"Juha"'
Publikováno v:
Scandinavian Journal of Primary Health Care, Vol 42, Iss 4, Pp 609-616 (2024)
Aim Machine learning techniques have demonstrated success in predictive modeling across various clinical cases. However, few studies have considered predicting the use of multisectoral health and social services among older adults. This research aims
Externí odkaz:
https://doaj.org/article/f132a7f5438e4be9be93bc1e33a4bebd
Autor:
Barış Yaşar, Nina Boskovic, Marilin Ivask, Jere Weltner, Eeva-Mari Jouhilahti, Piibe Vill, Tiina Skoog, Ülle Jaakma, Juha Kere, Thomas R. Bürglin, Shintaro Katayama, Tõnis Org, Ants Kurg
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Embryonic genome activation (EGA) is a critical step in early embryonic development, as it marks the transition from relying on maternal factors to the initiation of transcription from embryo’s own genome. The factors associated
Externí odkaz:
https://doaj.org/article/cd92ba7b704641dd8d6998ca2c0bee40
Autor:
Fedik Rahimov, Pekka Nieminen, Priyanka Kumari, Emma Juuri, Tiit Nikopensius, Kitt Paraiso, Jakob German, Antti Karvanen, Mart Kals, Abdelrahman G. Elnahas, Juha Karjalainen, Mitja Kurki, Aarno Palotie, FinnGen, Estonian Biobank Research Team, Arja Heliövaara, Tõnu Esko, Sakari Jukarainen, Priit Palta, Andrea Ganna, Anjali P. Patni, Daniel Mar, Karol Bomsztyk, Julie Mathieu, Hannele Ruohola-Baker, Axel Visel, Walid D. Fakhouri, Brian C. Schutte, Robert A. Cornell, David P. Rice
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract In Finland, the frequency of isolated cleft palate (CP) is higher than that of isolated cleft lip with or without cleft palate (CL/P). This trend contrasts to that in other European countries but its genetic underpinnings are unknown. We con
Externí odkaz:
https://doaj.org/article/deb6024dc0564416a196dc00f1b96ded
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Suicidal persons’ contacts with services present a key opportunity for suicide prevention. However, interventions by services are not always effective. A deeper understanding of suicidal service users’ agency and its implicati
Externí odkaz:
https://doaj.org/article/70a72912a0474a79a99d6f46a92fc3e6
Autor:
Matthias Hörtenhuber, Marjo K. Hytönen, Abdul Kadir Mukarram, Meharji Arumilli, César L. Araujo, Ileana Quintero, Pernilla Syrjä, Niina Airas, Maria Kaukonen, Kaisa Kyöstilä, Julia Niskanen, Tarja S. Jokinen, Faezeh Mottaghitalab, Işıl Takan, Noora Salokorpi, Amitha Raman, Irene Stevens, Antti Iivanainen, Masahito Yoshihara, Oleg Gusev, Danika Bannasch, Antti Sukura, Jeffrey J. Schoenebeck, DoGA Consortium, Sini Ezer, Shintaro Katayama, Carsten O. Daub, Juha Kere, Hannes Lohi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The dog, Canis lupus familiaris, is an important model for studying human diseases. Unlike many model organisms, the dog genome has a comparatively poor functional annotation, which hampers gene discovery for development, morphology, disease
Externí odkaz:
https://doaj.org/article/7894452dee5b4ca9b19fbe1f626becc8
Autor:
Maria Francesca Di Feo, Ali Oghabian, Ella Nippala, Mathias Gautel, Heinz Jungbluth, Francesca Forzano, Edoardo Malfatti, Claudia Castiglioni, Ilona Krey, David Gomez Andres, Angela F. Brady, Maria Iascone, Anna Cereda, Lidia Pezzani, Daniel Natera De Benito, Andres Nascimiento Osorio, Berta Estévez Arias, Sergei A. Kurbatov, Tania Attie‐Bitach, Sheela Nampoothiri, Erin Ryan, Michelle Morrow, Svetlana Gorokhova, Brigitte Chabrol, Juha Sinisalo, Heli Tolppanen, Johanna Tolva, Francina Munell, Jessica Camacho Soriano, Maria Angeles Sanchez Duran, Mridul Johari, Homa Tajsharghi, Peter Hackman, Bjarne Udd, Marco Savarese
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 10, Pp 2745-2755 (2024)
Abstract Objective Biallelic titin truncating variants (TTNtv) have been associated with a wide phenotypic spectrum, ranging from complex prenatal muscle diseases with dysmorphic features to adult‐onset limb‐girdle muscular dystrophy, with or wit
Externí odkaz:
https://doaj.org/article/56fcca32800d4caeb1e23bc0b7d6e783
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-8 (2024)
Abstract It is widely acknowledged that the intensity, frequency and duration of heatwaves are increasing worldwide, including the Arctic. However, less attention has been paid to the land area affected by heatwaves. Here, using atmospheric reanalysi
Externí odkaz:
https://doaj.org/article/cff42213280441d4be09035e9a739cb8
Autor:
Mikhail Sofiev, Julia Palamarchuk, Rostislav Kouznetsov, Tamuna Abramidze, Beverley Adams-Groom, Célia M. Antunes, Arturo H. Ariño, Maximilian Bastl, Jordina Belmonte, Uwe E. Berger, Maira Bonini, Nicolas Bruffaerts, Jeroen Buters, Paloma Cariñanos, Sevcan Celenk, Valentina Ceriotti, Athanasios Charalampopoulos, Yolanda Clewlow, Bernard Clot, Aslog Dahl, Athanasios Damialis, Concepción De Linares, Letty A. De Weger, Lukas Dirr, Agneta Ekebom, Yalda Fatahi, María Fernández González, Delia Fernández González, Santiago Fernández-Rodríguez, Carmen Galán, Björn Gedda, Regula Gehrig, Carmi Geller Bernstein, Nestor Gonzalez Roldan, Lukasz Grewling, Lenka Hajkova, Risto Hänninen, François Hentges, Juha Jantunen, Evgeny Kadantsev, Idalia Kasprzyk, Mathilde Kloster, Katarzyna Kluska, Mieke Koenders, Janka Lafférsová, Poliana Mihaela Leru, Agnieszka Lipiec, Maria Louna-Korteniemi, Donát Magyar, Barbara Majkowska-Wojciechowska, Mika Mäkelä, Mirjana Mitrovic, Dorota Myszkowska, Gilles Oliver, Pia Östensson, Rosa Pérez-Badia, Krystyna Piotrowska-Weryszko, Marje Prank, Ewa Maria Przedpelska-Wasowicz, Sanna Pätsi, F. Javier Rodríguyez Rajo, Hallvard Ramfjord, Joanna Rapiejko, Victoria Rodinkova, Jesús Rojo, Luis Ruiz-Valenzuela, Ondrej Rybnicek, Annika Saarto, Ingrida Sauliene, Andreja Kofol Seliger, Elena Severova, Valentina Shalaboda, Branko Sikoparija, Pilvi Siljamo, Joana Soares, Olga Sozinova, Anders Stangel, Barbara Stjepanović, Erik Teinemaa, Svyatoslav Tyuryakov, M. Mar Trigo, Andreas Uppstu, Mart Vill, Julius Vira, Nicolas Visez, Tiina Vitikainen, Despoina Vokou, Elżbieta Weryszko-Chmielewska, Ari Karppinen
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-19 (2024)
Abstract The dataset presents a 43 year-long reanalysis of pollen seasons for three major allergenic genera of trees in Europe: alder (Alnus), birch (Betula), and olive (Olea). Driven by the meteorological reanalysis ERA5, the atmospheric composition
Externí odkaz:
https://doaj.org/article/a2af37d3efa64adba2c4076fd1067b93
Autor:
Melissa A. Graewert, Maria Volkova, Klara Jonasson, Juha A. E. Määttä, Tobias Gräwert, Samara Mamidi, Natalia Kulesskaya, Johan Evenäs, Richard E. Johnsson, Dmitri Svergun, Arnab Bhattacharjee, Henri J. Huttunen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Cerebral dopamine neurotrophic factor (CDNF) is an unconventional neurotrophic factor that is a disease-modifying drug candidate for Parkinson’s disease. CDNF has pleiotropic protective effects on stressed cells, but its mechanism of actio
Externí odkaz:
https://doaj.org/article/96e49cedbeaa44d2becdda52aada34c8
Autor:
Sanna Cederqvist, Tapio Flinkkilä, Antti Tuominen, Markus Sormaala, Jari Ylinen, Hannu Kautiainen, Kai Sirniö, Konsta Pamilo, Ilkka Kiviranta, Juha Paloneva, on behalf of the SURFIN group
Publikováno v:
Bone & Joint Open, Vol 5, Iss 9, Pp 793-799 (2024)
Aims: Rotator cuff disease (RCD) can considerably decrease quality of life. Here, we investigated whether health-related quality of life (HRQoL) influences the need for surgery in patients with RCD. Methods: We performed an analysis of 417 patients w
Externí odkaz:
https://doaj.org/article/6f6272305d8b4d16ae274f9b10d35631