Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jugal P, Dhandhukia"'
Publikováno v:
Bioconjug Chem
Human granulocyte-macrophage colony-stimulating factor (hGMCSF) is crucial in the immune system as it stimulates survival, proliferation, differentiation, and functional activation of myeloid hematopoietic cells. hGMCSF is integral to approved therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1608f49312abbb705fec3bd144813243
https://pubmed.ncbi.nlm.nih.gov/32319752
https://pubmed.ncbi.nlm.nih.gov/32319752
Publikováno v:
Protein Science. 26:1785-1795
Elastin-Like Polypeptides (ELPs) reversibly phase separate in response to changes in temperature, pressure, concentration, pH, and ionic species. While powerful triggers, biological microenvironments present a multitude of more specific biological cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c36cd84d750c6c894184e80c87ec3ac
https://doi.org/10.1002/pro.3215
https://doi.org/10.1002/pro.3215
Autor:
Jordan Despanie, J. Andrew MacKay, Jugal P. Dhandhukia, David R. Tyrpak, Zhe Li, Arjun Mehta, Santosh Peddi, Shruti Singh Kakan
Publikováno v:
Theranostics
Recombinant Elastin-Like Polypeptides (ELPs) serve as attractive scaffolds for nanoformulations because they can be charge-neutral, water soluble, high molecular weight, monodisperse, biodegradable, and decorated with functional proteins. We recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378a8ffed6bd32285af70d3b5833507f
https://doi.org/10.7150/thno.19981
https://doi.org/10.7150/thno.19981
Publikováno v:
Journal of Controlled Release. 240:93-108
Elastin-like polypeptides (ELPs) constitute a genetically engineered class of ‘protein polymers’ derived from human tropoelastin. They exhibit a reversible phase separation whereby samples remain soluble below a transition temperature (Tt) but fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a117fb408c1876db14396213d1555c16
https://doi.org/10.1016/j.jconrel.2015.11.010
https://doi.org/10.1016/j.jconrel.2015.11.010
Autor:
Jugal P. Dhandhukia, Dab Brill, Siti M. Janib, J. Andrew MacKay, Yi-An Lin, Pu Shi, Wan Wang, Suhaas Aluri, Santosh Peddi, Shuanglong Liu, Yaping Ju, Honggang Cui, Zhe Li
Recombinant protein-polymer scaffolds such as elastin-like polypeptides (ELPs) offer drug-delivery opportunities including biocompatibility, monodispersity, and multifunctionality. We recently reported that the fusion of FK-506 binding protein 12 (FK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebf0308f8a9f6195b6afe1b2f7ef8c3
https://europepmc.org/articles/PMC5779105/
https://europepmc.org/articles/PMC5779105/
Publikováno v:
Protein science : a publication of the Protein Society. 26(9)
Elastin‐Like Polypeptides (ELPs) reversibly phase separate in response to changes in temperature, pressure, concentration, pH, and ionic species. While powerful triggers, biological microenvironments present a multitude of more specific biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dfcbb89f26f33ec1e9d2aefe138bce6
https://pubmed.ncbi.nlm.nih.gov/28639381
https://pubmed.ncbi.nlm.nih.gov/28639381
Autor:
Siyu Liu, J. Andrew MacKay, Srikanth Reddy Janga, Stan G. Louie, Sarah F. Hamm-Alvarez, Mihir Shah, Kathleen E. Rodgers, Jugal P. Dhandhukia, Pu Shi, Maria C. Edman
Publikováno v:
Journal of Controlled Release. 171:269-279
Sjögren’s syndrome (SjS) is a chronic autoimmune disease characterized initially by lymphocytic infiltration and destruction of exocrine glands, followed by systemic organ damage and B-cell lymphoma. Conventional treatment is based on management o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c978edcfbec1b12d6432e5df4d654b7
https://doi.org/10.1016/j.jconrel.2013.07.016
https://doi.org/10.1016/j.jconrel.2013.07.016
Autor:
Pu Shi, J. Andrew MacKay, Yi-An Lin, Honggang Cui, Jugal P. Dhandhukia, Maria C. Edman, Suhaas Aluri, Mihir Shah
Numerous nanocarriers of small molecules depend on either non-specific physical encapsulation or direct covalent linkage. In contrast, this manuscript explores an alternative encapsulation strategy based on high-specificity avidity between a small mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785ea3ba4e482dbf368fadd08a4d8d18
https://europepmc.org/articles/PMC3795821/
https://europepmc.org/articles/PMC3795821/
Elastin-like polypeptides (ELPs) are protein polymers that reversibly phase separate in response to increased temperature, pressure, concentration, ionic strength, and molecular weight. If it were possible to engineer their phase separation to respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4874e8d2af5dacf6ef124dd1f177783
https://europepmc.org/articles/PMC3721738/
https://europepmc.org/articles/PMC3721738/