Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jugajyoti, Baruah"'
Autor:
Oluwarotimi O. Folorunso, Stephanie E. Brown, Jugajyoti Baruah, Theresa L. Harvey, Shekib A. Jami, Inna Radzishevsky, Herman Wolosker, James M. McNally, John A. Gray, Anju Vasudevan, Darrick T. Balu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The proper development and function of telencephalic GABAergic interneurons is critical for maintaining the excitation and inhibition (E/I) balance in cortical circuits. Glutamate contributes to cortical interneuron (CIN) development via N-m
Externí odkaz:
https://doaj.org/article/c1a3de421db14b62abea4c8f005bf011
Autor:
Jugajyoti Baruah, Kishore K. Wary
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2020)
Exosomes have been described as nanoscale membranous extracellular vesicles that emerge from a variety of cells and tissues and are enriched with biologically active genomic and non-genomic biomolecules capable of transducing cell to cell communicati
Externí odkaz:
https://doaj.org/article/1ec484c732524df3b217df80c2eacc7d
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
Our understanding of the etiological mechanisms leading up to epilepsy has undergone radical changes over time due to more insights into the complexity of the disease. The traditional hypothesis emphasized network hyperexcitability and an imbalance o
Externí odkaz:
https://doaj.org/article/7b588a2a71a4408799268a3bc7350165
Autor:
Myung-Jin Oh, Chongxu Zhang, Elizabeth LeMaster, Crystal Adamos, Evgeny Berdyshev, Yedida Bogachkov, Erin E. Kohler, Jugajyoti Baruah, Yun Fang, Dean E. Schraufnagel, Kishore K. Wary, Irena Levitan
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 5, Pp 791-808 (2016)
Endothelial biomechanics is emerging as a key factor in endothelial function. Here, we address the mechanisms of endothelial stiffening induced by oxidized LDL (oxLDL) and investigate the role of oxLDL in lumen formation. We show that oxLDL-induced e
Externí odkaz:
https://doaj.org/article/6483c693e19b4ae58ce7388fa48fa1ab
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176496 (2017)
The human epigenome is plastic. The goal of this study was to address if fibroblast cells can be epigenetically modified to promote neovessel formation.Here, we used highly abundant human adult dermal fibroblast cells (hADFCs) that were treated with
Externí odkaz:
https://doaj.org/article/e3bf07ba78ea41bfb2fdac7638c796c5
Autor:
Suhnrita Chaudhuri, Jugajyoti Baruah, Ryan T. Hitzman, Victoria Mastej, Kishore K. Wary, Isabella M.B. Ribeiro, Cassondra Axen
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Nanog is expressed in adult endothelial cells (ECs) at a low-level, however, its functional significance is not known. The goal of our study was to elucidate the role of Nanog in
Objective: Nanog is expressed in adult endothelial cells (ECs) at a low-level, however, its functional significance is not known. The goal of our study was to elucidate the role of Nanog in
Autor:
Jugajyoti Baruah, Yong Kee Choi, Sivan Subburaju, Abdallah Elkhal, Sarah Kaye, Sangmi Chung, Yeqi Nian, Jahan Khalili, Debkanya Datta, Anju Vasudevan
Publikováno v:
Molecular Psychiatry
Abnormalities of or reductions in GABAergic interneurons are implicated in the pathology of severe neuropsychiatric disorders, for which effective treatments are still elusive. Transplantation of human stem cell-derived interneurons is a promising ce
Autor:
Anju Vasudevan, Jugajyoti Baruah
Publikováno v:
The open neurology journal
The mammalian brain receives the lion’s share of the body’s blood supply and is a highly vascularized organ. The vascular and nervous systems arise at two distinct time points of embryogenesis; however, their functions tend to overlap or compleme
Autor:
Dai Fukumura, Jugajyoti Baruah, Jun Ren, Ashwin S. Kumar, Anju Vasudevan, Yong Kee Choi, Rakesh K. Jain, Gábor Szabó, Debkanya Datta, Abdallah Elkhal, Sivan Subburaju, Sarah Kaye
Publikováno v:
Science Advances. 6
Intrinsic defects within blood vessels from the earliest developmental time points can directly contribute to psychiatric disease origin. Here, we show that nicotinamide adenine dinucleotide (NAD+), administered during a critical window of prenatal d
Autor:
Sivan, Subburaju, Sarah, Kaye, Yong Kee, Choi, Jugajyoti, Baruah, Debkanya, Datta, Jun, Ren, Ashwin Srinivasan, Kumar, Gabor, Szabo, Dai, Fukumura, Rakesh K, Jain, Abdallah, Elkhal, Anju, Vasudevan
Publikováno v:
Science Advances
Prenatal NAD+ treatment can rescue abnormal brain development and prevent the origin of mental illness.
Intrinsic defects within blood vessels from the earliest developmental time points can directly contribute to psychiatric disease origin. Her
Intrinsic defects within blood vessels from the earliest developmental time points can directly contribute to psychiatric disease origin. Her