Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jufang Chang"'
Autor:
Amanda Heard, Jack H. Landmann, Ava R. Hansen, Alkmini Papadopolou, Yu-Sung Hsu, Mehmet Emrah Selli, John M. Warrington, John Lattin, Jufang Chang, Helen Ha, Martina Haug-Kroeper, Balraj Doray, Saar Gill, Marco Ruella, Katharina E. Hayer, Matthew D. Weitzman, Abby M. Green, Regina Fluhrer, Nathan Singh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Loss of surface CD19 expression by leukemic cells leads to resistance and relapse to CD19-targeted CAR-T therapies. Here the authors show that loss of SPPL3 in malignant B cells results in hyperglycosylation of CD19.
Externí odkaz:
https://doaj.org/article/0f7c94a068e44180b9af36e2164d17d4
Autor:
Bin Zhang, Jufang Chang, Ming Fu, Jie Huang, Rakesh Kashyap, Ezequiel Salavaggione, Sanjay Jain, Shashikant Kulkarni, Matthew A. Deardorff, Maria L. Giovannucci Uzielli, Dale Dorsett, David C. Beebe, Patrick Y. Jay, Robert O. Heuckeroth, Ian Krantz, Jeffrey Milbrandt
Publikováno v:
PLoS ONE, Vol 4, Iss 5 (2009)
Externí odkaz:
https://doaj.org/article/257909b9be734385b37cc20ee0ca192f
Autor:
Bin Zhang, Jufang Chang, Ming Fu, Jie Huang, Rakesh Kashyap, Ezequiel Salavaggione, Sanjay Jain, Shashikant Kulkarni, Matthew A Deardorff, Maria L Giovannucci Uzielli, Dale Dorsett, David C Beebe, Patrick Y Jay, Robert O Heuckeroth, Ian Krantz, Jeffrey Milbrandt
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5232 (2009)
Cornelia de Lange syndrome (CdLS), a disorder caused by mutations in cohesion proteins, is characterized by multisystem developmental abnormalities. PDS5, a cohesion protein, is important for proper chromosome segregation in lower organisms and has t
Externí odkaz:
https://doaj.org/article/e2e6fd0691444438ad56718d342b4f0b
Autor:
Armin Ghobadi, Jack H. Landmann, Alun Carter, Matthew L. Cooper, Mehmet Emrah Selli, Jufang Chang, Matthew Baker, Christopher A. Miller, Francesca Ferraro, David Y. Chen, Amanda M. Smith, Taylor A. LaValle, Eric J. Duncavage, Justin Chou, Victor Tam, Joseph M. Benoun, Jenny Nater, Nathalie Scholler, Francesca Milletti, Remus Vezan, Adrian Bot, John M. Rossi, Nathan Singh
Publikováno v:
Blood Advances. 6:5634-5640
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d8f41309b64dd6dcd54863fffe9d9b
https://doi.org/10.1182/bloodadvances.2022007705
https://doi.org/10.1182/bloodadvances.2022007705
Autor:
Mehmet Emrah Selli, Jack Landmann, John Lattin, Amanda Heard, John Warrington, Helen Ha, Jufang Chang, Natalie Kingston, Graham Hogg, Mark Foster, Samantha Kersting-Schadek, Marina Terekhova, David DeNardo, Todd A. Fehniger, Maxim Artyomov, Nathan Singh
Publikováno v:
Blood. 140:2354-2355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a210822bfce2783bc77d669e3e75385
https://doi.org/10.1182/blood-2022-159687
https://doi.org/10.1182/blood-2022-159687
Autor:
Katharina E. Hayer, Balraj Doray, Marco Ruella, Amanda Heard, Jufang Chang, Matthew D. Weitzman, Saar Gill, John Lattin, Nathan Singh, Regina Fluhrer, Jack Landmann, Mehmet Emrah Selli, Helen Ha, Abby M. Green
Publikováno v:
Blood. 138:1721-1721
Chimeric antigen receptor-engineered T cells targeting CD19 (CART19) have revolutionized the management of relapsed and refractory B cell malignancies. Despite high initial response rates, many patients with acute lymphoblastic leukemia (ALL) ultimat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa8d5a31dd2ad49424e14d7113732bbe
https://doi.org/10.1182/blood-2021-146651
https://doi.org/10.1182/blood-2021-146651
Publikováno v:
Best Practice & Research Clinical Haematology. 34:101304
Chimeric antigen receptor (CAR) T cells have revolutionized the management of B cell malignancies. These synthetic molecules are composed of peptide fragments from several distinct immune cell proteins and link highly-specific antigen recognition wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2029ebc41cd99f1ddcf0b30901eb8c36
https://doi.org/10.1016/j.beha.2021.101304
https://doi.org/10.1016/j.beha.2021.101304
Autor:
Jufang Chang, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt, Bhupinder P. S. Vohra, Bradley R. Miller
Publikováno v:
The Journal of Neuroscience. 30:13729-13738
Axonal degeneration is a hallmark of many debilitating neurological disorders and is thought to be regulated by mechanisms distinct from those governing cell body death. Recently, caspase 6 activation via amyloid precursor protein (APP) cleavage and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258b6ee7f7c5c26f595fd5a1701197b3
https://doi.org/10.1523/jneurosci.2939-10.2010
https://doi.org/10.1523/jneurosci.2939-10.2010
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of Ame, 107(50), 21836-21841. National Academy of Sciences
Cellular metabolism alters patterns of gene expression through a variety of mechanisms, including alterations in histone modifications and transcription factor activity. Nicotinamide adenine dinucleotide (NAD)–dependent proteins such as poly(ADP ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862461552c0bc5a6a499aec0395d3bd1
https://doi.org/10.1073/pnas.1002130107
https://doi.org/10.1073/pnas.1002130107
Autor:
C Hession, Melissa Levesque, Zhigang He, John M. Mccoy, Bruce D. Trapp, Jufang Chang, Martin L. Scott, Greg Thill, Xinhua Lee, Svetlane Shulag-Morskaya, Dinah W. Y. Sah, Sha Mi, Zhaohui Shao, Robert H. Miller, Vincent Jung, R. Blake Pepinsky, Mingdi Zhang
Publikováno v:
Nature Neuroscience. 8:745-751
The control of myelination by oligodendrocytes in the CNS is poorly understood. Here we show that LINGO-1 is an important negative regulator of this critical process. LINGO-1 is expressed in oligodendrocytes. Attenuation of its function by dominant-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0ec3129a06a231953f1c4ada804fed
https://doi.org/10.1038/nn1460
https://doi.org/10.1038/nn1460