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pro vyhledávání: '"Juexiao Wang"'
Publikováno v:
Nature Chemistry. 9:1222-1228
Complex DNA sequences are difficult to detect and profile, but are important contributors to human health and disease. Existing hybridization probes lack the capability to selectively bind and enrich hypervariable, long or repetitive sequences. Here,
Autor:
Irena Pekker, David Zhang, Emily R Evans, Celine Ngouenet, Alessandro Pinto, Joseph M. Beechem, Lucia R. Wu, Juexiao Wang, John Z. Fang, Richard Kemble Boykin, Philippa J. Webster
Publikováno v:
Nature methods
In silico designed nucleic acid probes and primers often fail to achieve favorable specificity and sensitivity tradeoffs on the first try, and iterative empirical sequence-based optimization is needed, particularly in multiplexed assays. Here, we pre
Autor:
Juexiao Wang, David Zhang
Publikováno v:
Nature chemistry
Hybridization of complementary sequences is one of the central tenets of nucleic acid chemistry; however, the unintended binding of closely related sequences limits the accuracy of hybridization-based approaches to analysing nucleic acids. Thermodyna
Autor:
Juexiao Wang, Huaiqiu Zhu
Publikováno v:
Acta Biophysica Sinica. 29:143