Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Juergen Strehlau"'
Autor:
Shazia Ashraf, Hiroki Kudo, Jia Rao, Atsuo Kikuchi, Eugen Widmeier, Jennifer A. Lawson, Weizhen Tan, Tobias Hermle, Jillian K. Warejko, Shirlee Shril, Merlin Airik, Tilman Jobst-Schwan, Svjetlana Lovric, Daniela A. Braun, Heon Yung Gee, David Schapiro, Amar J. Majmundar, Carolin E. Sadowski, Werner L. Pabst, Ankana Daga, Amelie T. van der Ven, Johanna M. Schmidt, Boon Chuan Low, Anjali Bansal Gupta, Brajendra K. Tripathi, Jenny Wong, Kirk Campbell, Kay Metcalfe, Denny Schanze, Tetsuya Niihori, Hiroshi Kaito, Kandai Nozu, Hiroyasu Tsukaguchi, Ryojiro Tanaka, Kiyoshi Hamahira, Yasuko Kobayashi, Takumi Takizawa, Ryo Funayama, Keiko Nakayama, Yoko Aoki, Naonori Kumagai, Kazumoto Iijima, Henry Fehrenbach, Jameela A. Kari, Sherif El Desoky, Sawsan Jalalah, Radovan Bogdanovic, Nataša Stajić, Hildegard Zappel, Assel Rakhmetova, Sharon-Rose Wassmer, Therese Jungraithmayr, Juergen Strehlau, Aravind Selvin Kumar, Arvind Bagga, Neveen A. Soliman, Shrikant M. Mane, Lewis Kaufman, Douglas R. Lowy, Mohamad A. Jairajpuri, Richard P. Lifton, York Pei, Martin Zenker, Shigeo Kure, Friedhelm Hildebrandt
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nephrotic syndrome is the second most common chronic kidney disease but there are no targeted treatment strategies available. Here the authors identify mutations of six genes codifying for proteins involved in cytoskeleton remodelling and modulation
Externí odkaz:
https://doaj.org/article/5fa7365ce28f4895a98f2773a190db3e
Autor:
Yasuko Kobayashi, Heon Yung Gee, Juergen Strehlau, York Pei, Shigeo Kure, Therese Jungraithmayr, Kirk N. Campbell, Shirlee Shril, Assel Rakhmetova, Weizhen Tan, Henry Fehrenbach, Mohamad Aman Jairajpuri, Amelie T. van der Ven, Sharon Rose Wassmer, Aravind Selvin Kumar, Friedhelm Hildebrandt, Naonori Kumagai, Neveen A. Soliman, Tilman Jobst-Schwan, Shrikant M. Mane, Jennifer A. Lawson, Atsuo Kikuchi, Ankana Daga, Boon Chuan Low, Hildegard Zappel, Denny Schanze, Martin Zenker, Svjetlana Lovric, Sherif El Desoky, Natasa Stajic, Kandai Nozu, Lewis Kaufman, Jameela A. Kari, Hiroki Kudo, Carolin E. Sadowski, Hiroyasu Tsukaguchi, Jenny Wong, Takumi Takizawa, Jillian K. Warejko, Kazumoto Iijima, Kay Metcalfe, David Schapiro, Daniela A. Braun, Johanna Magdalena Schmidt, Tobias Hermle, Brajendra K. Tripathi, Hiroshi Kaito, Eugen Widmeier, Radovan Bogdanovic, Merlin Airik, Douglas R. Lowy, Keiko Nakayama, Werner L. Pabst, Ryo Funayama, Arvind Bagga, Amar J. Majmundar, Ryojiro Tanaka, Richard P. Lifton, Tetsuya Niihori, Jia Rao, Kiyoshi Hamahira, Sawsan M Jalalah, Yoko Aoki, Anjali Gupta, Shazia Ashraf
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Ashraf, S, Kudo, H, Rao, J, Kikuchi, A, Widmeier, E, Lawson, J A, Tan, W, Hermle, T, Warejko, J K, Shril, S, Airik, M, Jobst-Schwan, T, Lovric, S, Braun, D A, Gee, H Y, Schapiro, D, Majmundar, A J, Sadowski, C E, Pabst, W L, Daga, A, Van Der Ven, A T, Schmidt, J M, Low, B C, Gupta, A B, Tripathi, B K, Wong, J, Campbell, K, Metcalfe, K, Schanze, D, Niihori, T, Kaito, H, Nozu, K, Tsukaguchi, H, Tanaka, R, Hamahira, K, Kobayashi, Y, Takizawa, T, Funayama, R, Nakayama, K, Aoki, Y, Kumagai, N, Iijima, K, Fehrenbach, H, Kari, J A, El Desoky, S, Jalalah, S, Bogdanovic, R, Stajić, N, Zappel, H, Rakhmetova, A, Wassmer, S R, Jungraithmayr, T, Strehlau, J, Kumar, A S, Bagga, A, Soliman, N A, Mane, S M, Kaufman, L, Lowy, D R, Jairajpuri, M A, Lifton, R P, Pei, Y, Zenker, M, Kure, S & Hildebrandt, F 2018, ' Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment ', Nature Communications, vol. 9, no. 1, 1960 . https://doi.org/10.1038/s41467-018-04193-w
Ashraf, S, Kudo, H, Rao, J, Kikuchi, A, Widmeier, E, Lawson, J A, Tan, W, Hermle, T, Warejko, J K, Shril, S, Airik, M, Jobst-Schwan, T, Lovric, S, Braun, D A, Gee, H Y, Schapiro, D, Majmundar, A J, Sadowski, C E, Pabst, W L, Daga, A, Van Der Ven, A T, Schmidt, J M, Low, B C, Gupta, A B, Tripathi, B K, Wong, J, Campbell, K, Metcalfe, K, Schanze, D, Niihori, T, Kaito, H, Nozu, K, Tsukaguchi, H, Tanaka, R, Hamahira, K, Kobayashi, Y, Takizawa, T, Funayama, R, Nakayama, K, Aoki, Y, Kumagai, N, Iijima, K, Fehrenbach, H, Kari, J A, El Desoky, S, Jalalah, S, Bogdanovic, R, Stajić, N, Zappel, H & Rakhmetova, A 2018, ' Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment ', Nature Communications, vol. 9, 1960 . https://doi.org/10.1038/s41467-018-04193-w
Nature Communications
Ashraf, S, Kudo, H, Rao, J, Kikuchi, A, Widmeier, E, Lawson, J A, Tan, W, Hermle, T, Warejko, J K, Shril, S, Airik, M, Jobst-Schwan, T, Lovric, S, Braun, D A, Gee, H Y, Schapiro, D, Majmundar, A J, Sadowski, C E, Pabst, W L, Daga, A, Van Der Ven, A T, Schmidt, J M, Low, B C, Gupta, A B, Tripathi, B K, Wong, J, Campbell, K, Metcalfe, K, Schanze, D, Niihori, T, Kaito, H, Nozu, K, Tsukaguchi, H, Tanaka, R, Hamahira, K, Kobayashi, Y, Takizawa, T, Funayama, R, Nakayama, K, Aoki, Y, Kumagai, N, Iijima, K, Fehrenbach, H, Kari, J A, El Desoky, S, Jalalah, S, Bogdanovic, R, Stajić, N, Zappel, H, Rakhmetova, A, Wassmer, S R, Jungraithmayr, T, Strehlau, J, Kumar, A S, Bagga, A, Soliman, N A, Mane, S M, Kaufman, L, Lowy, D R, Jairajpuri, M A, Lifton, R P, Pei, Y, Zenker, M, Kure, S & Hildebrandt, F 2018, ' Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment ', Nature Communications, vol. 9, no. 1, 1960 . https://doi.org/10.1038/s41467-018-04193-w
Ashraf, S, Kudo, H, Rao, J, Kikuchi, A, Widmeier, E, Lawson, J A, Tan, W, Hermle, T, Warejko, J K, Shril, S, Airik, M, Jobst-Schwan, T, Lovric, S, Braun, D A, Gee, H Y, Schapiro, D, Majmundar, A J, Sadowski, C E, Pabst, W L, Daga, A, Van Der Ven, A T, Schmidt, J M, Low, B C, Gupta, A B, Tripathi, B K, Wong, J, Campbell, K, Metcalfe, K, Schanze, D, Niihori, T, Kaito, H, Nozu, K, Tsukaguchi, H, Tanaka, R, Hamahira, K, Kobayashi, Y, Takizawa, T, Funayama, R, Nakayama, K, Aoki, Y, Kumagai, N, Iijima, K, Fehrenbach, H, Kari, J A, El Desoky, S, Jalalah, S, Bogdanovic, R, Stajić, N, Zappel, H & Rakhmetova, A 2018, ' Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment ', Nature Communications, vol. 9, 1960 . https://doi.org/10.1038/s41467-018-04193-w
No efficient treatment exists for nephrotic syndrome (NS), a frequent cause of chronic kidney disease. Here we show mutations in six different genes (MAGI2, TNS2, DLC1, CDK20, ITSN1, ITSN2) as causing NS in 17 families with partially treatment-sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec1a4bdf4207f4f2354614db43fc05b
https://doi.org/10.1038/s41467-018-04193-w
https://doi.org/10.1038/s41467-018-04193-w
Autor:
Emanuela P. Santoro, Thomas G. Wells, Shahnaz Shahinfar, Gilbert W. Gleim, Chun Lam, Tom Loeys, Juergen Strehlau, Nicholas J. A. Webb, Denise Manas
Publikováno v:
Clinical Journal of the American Society of Nephrology. 5:417-424
Background and objectives: No large, randomized, double-blind trials in children with proteinuria treated with angiotensinconverting enzyme inhibitors or angiotensin receptor blockers have previously been reported. Design, setting, participants, & me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10ceb7283ed1da7b523e5eb23fa8852
https://doi.org/10.2215/cjn.06620909
https://doi.org/10.2215/cjn.06620909
Autor:
Juergen Strehlau, Michael Mengel, Paul C. Grimm, Thomas Henne, Lars Pape, Jochen H. H. Ehrich, Gisela Offner
Publikováno v:
Transplantation. 76:955-958
BACKGROUND Chronic allograft nephropathy (CAN) has become the predominant limiting factor for long-term transplant survival. A cardinal histomorphologic correlate for CAN is interstitial fibrosis. Currently, no method has been established in routine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2cacce9b5df4658543535f77b05d94a
https://doi.org/10.1097/01.tp.0000078899.62040.e5
https://doi.org/10.1097/01.tp.0000078899.62040.e5
Publikováno v:
Nephrology Dialysis Transplantation. 17:573-579
Inflammatory, fibrogenic or apoptotic processes in the kidney are regulated by intra- and intercellular mediators. Intrarenal upregulation of genes may precede structural changes by days and can be examined in extremely small amounts of tissue. With
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c816d739c6c39f403ebef5359ccd0883
https://doi.org/10.1093/ndt/17.4.573
https://doi.org/10.1093/ndt/17.4.573
Autor:
Gisela Offner, B Nashan, Juergen Klempnauer, Juergen Strehlau, Lars Pape, Kay Latta, Jochen H. H. Ehrich, Thomas Henne
Publikováno v:
Nephrology Dialysis Transplantation. 17:276-280
BACKGROUND Introduction of IL-2-receptor antagonists has led to significantly decreasing numbers of acute rejection episodes in renal transplantation in adults. No data are available in paediatric recipients. METHODS Between 1997 and 2000, 78 renal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1160d2f74f72c79c4a8a4807a10f103
https://doi.org/10.1093/ndt/17.2.276
https://doi.org/10.1093/ndt/17.2.276
Autor:
Juergen Strehlau
Publikováno v:
Pediatric Transplantation. 7:4-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2d1119fd3975122a9b562a06382a7ae
https://doi.org/10.1034/j.1399-3046.2003.2e073.x
https://doi.org/10.1034/j.1399-3046.2003.2e073.x
Publikováno v:
Pediatric Transplantation. 6:337-339
We discuss the case of an 18-year-old-boy presenting with relapsing fever, arthralgia, myalgia and renal failure, 7 yr after renal transplantation. A thorough diagnostic work-up for infectious and inflammatory diseases revealed a mastoiditis and atyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fce80b4f8f77a5de67fc13bbb64c42
https://doi.org/10.1034/j.1399-3046.2002.02002.x
https://doi.org/10.1034/j.1399-3046.2002.02002.x
Autor:
Juergen Strehlau, Chun Lam, Celine Le Bailly De Tilleghem, Gilbert W. Gleim, Shahnaz Shahinfar, Nicholas J. A. Webb, Thomas G. Wells
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 26(8)
No prospective, randomized, double-blind trials of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers have previously been reported in adults or children with proteinuria secondary to Alport syndrome.This 12-week, double-blind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8d53bba351b87fbf8db402ca28094d
https://pubmed.ncbi.nlm.nih.gov/21285125
https://pubmed.ncbi.nlm.nih.gov/21285125
Autor:
Verena Broecker, Bjoern Nashan, Martina Koch, Corinna Doege, Annice Heratizadeh, Juergen Strehlau, Michael Mengel
Publikováno v:
Transplant immunology. 19(3-4)
Background Chronic allograft injury induced by immunological as well as non-immunological mechanisms is still a major cause of long-term graft loss after renal transplantation. Major histocompatibility complex (MHC) incompatibilities as well as donor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef8f767679fdce33c7a139d317a6d68
https://pubmed.ncbi.nlm.nih.gov/18595711
https://pubmed.ncbi.nlm.nih.gov/18595711