Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Juergen Ruland"'
Autor:
Kilian Kirmes, Marc Rosenbaum, Rosanna Gosetti, Markus List, Marina Lukas, Dario Bongiovanni, Juergen Ruland, Simon Weidlich, Moritz von Scheidt, Isabell Bernlochner, Gianluigi Condorelli, Melissa Klug, Karl-Ludwig Laugwitz, Olga Lazareva, Jan Baumbach, Christoph D. Spinner
SARS-CoV-2 infection induces a coagulopathy characterized by platelet activation and a hypercoagulable state with an increased incidence of cardiovascular events. The viral spike protein S has been reported to enhance thrombosis formation, stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b35eda6a40fb3ef07ca77c5ecebca9c
https://doi.org/10.1101/2021.05.18.21257324
https://doi.org/10.1101/2021.05.18.21257324
Autor:
Christiane Funk, Vanina E. Alvarez, Heinz D. Osiewacz, Juan José Cazzulo, Simon Stael, Boris Zhivotovsky, Chang Jae Choi, Frank Madeo, Jens Staal, Kailash C. Pandey, Lynn A. Megeney, Yigong Shi, Magali Casanova, Andrei Smertenko, Maurício F.M. Machado, Eric Lam, Renier A. L. van der Hoorn, Juergen Ruland, Ilana Berman-Frank, Panagiotis N. Moschou, Peter V. Bozhkov, Jeremy C. Mottram, Kay D. Bidle, Jerry Ståhlberg, Rudi Beyaert, Christopher M. Overall, Frédéric Bornancin, Kris Gevaert, Margot Thome, Assaf Vardi, Núria S. Coll, Patrick Gallois, Frank Van Breusegem, Thomas Nyström, Vishva M. Dixit, Marko Dolinar, Maria F. Suarez, Stephan Hailfinger, Nicolas Fasel, Emilio Gutierrez-Beltran, John A. Berges, Anna Linusson, Hannele Tuominen, Daniel Krappmann, Guy S. Salvesen, Marina Klemenčič, Elena A. Minina, Eugene V. Koonin
Publikováno v:
Molecular Cell
Molecular Cell, 2020, 77 (5), pp.927-929. ⟨10.1016/j.molcel.2019.12.020⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Molecular Cell, Elsevier, 2020, 77 (5), pp.927-929. ⟨10.1016/j.molcel.2019.12.020⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Mol Cell
MOLECULAR CELL
Mol. Cell 77, 927-929 (2020)
Molecular Cell, 2020, 77 (5), pp.927-929. ⟨10.1016/j.molcel.2019.12.020⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Molecular Cell, Elsevier, 2020, 77 (5), pp.927-929. ⟨10.1016/j.molcel.2019.12.020⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Mol Cell
MOLECULAR CELL
Mol. Cell 77, 927-929 (2020)
Metacaspases and paracaspases are proteases that were first identified as containing a caspase-like structural fold (Uren et al., 2000). Like caspases, metacaspases and paracaspases are multifunctional proteins regulating diverse biological phenomena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca139f3f1cce5c86eb98c1db290f79e8
https://doi.org/10.1016/j.molcel.2019.12.020
https://doi.org/10.1016/j.molcel.2019.12.020
Autor:
Stefania Re Depaolini, Tõnu Vooder, Paul-Albert Koenig, Jana Zecha, Mathias Wilhelm, Florian Bassermann, Harald Polzer, Tobias Schmidt, Hannes Hahne, Jan Huenges, Judith Schlegl, Axel Walch, Irmela Jeremias, Stephanie Heinzlmeir, Binje Vick, Bernhard Kuster, Bjoern-Oliver Gohlke, Dominic Helm, Karsten Spiekermann, Karl Kramer, Daniel P Zolg, Neeme Tõnisson, Juergen Ruland, Hans-Christian Ehrlich, Annette Feuchtinger, Wilhelm Becker, Benjamin Ruprecht, Katharina Götze, Svenja Petzoldt, Stephan Aiche, Lars Rueckert, Susan Klaeger, Sabine Schneider, Melanie Schoof, Anne-Kathrin Garz, Maria Reinecke, G. Canevari, Eduard R. Felder, Guillaume Médard, Chen Meng, Philipp A. Greif, Gian Kayser, Elena Casale, Zhixiang Wu, Robert Preissner, Heiner Koch, Huichao Qiao, Katrin Reiter
Publikováno v:
Science
Science 358:eaan4368 (2017)
Science 358:eaan4368 (2017)
An atlas for drug interactions Kinase inhibitors are an important class of drugs that block certain enzymes involved in diseases such as cancer and inflammatory disorders. There are hundreds of kinases within the human body, so knowing the kinase “
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c60ba549cf2fdbc5a8c4a800cc31b3
Autor:
Desheng Hu, Torben Gehring, Jan Kranich, Richard A. Griesbach, Vigo Heissmeyer, Thomas Brocker, Andrea C. Eitelhuber, Andrea Oeckinghaus, Marc Schmidt-Supprian, Arianna Bertossi, Daniel Krappmann, Ute Greczmiel, Isabel Meininger, Andreas Gewies, Juergen Ruland, Thomas Seeholzer, Florian Heyd
Publikováno v:
Nature Communications
Nat. Commun. 7:11292 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nat. Commun. 7:11292 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
MALT1 channels proximal T-cell receptor (TCR) signalling to downstream signalling pathways. With MALT1A and MALT1B two conserved splice variants exist and we demonstrate here that MALT1 alternative splicing supports optimal T-cell activation. Inclusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74531d48192572ba15b416c567345178
http://europepmc.org/articles/PMC4832065
http://europepmc.org/articles/PMC4832065
Autor:
Susanne Roth, Assa Yeroslaviz, Xosé R. Bustelo, Hanna Bergmann, Konstantin Neumann, Melissa D. Johnson, Mauricio Menacho-Márquez, Mihai G. Netea, Victor L. J. Tybulewicz, Clarissa Prazeres da Costa, Bianca Habermann, Vinod Kumar, Juergen Ruland, Lesley Vanes, Martin Jaeger, Paul-Albert Koenig
Publikováno v:
Cell Reports, 17, 2572-2583
Cell Reports, 17, 10, pp. 2572-2583
Cell reports, 17(10), 2572-2583. CELL PRESS
Cell Reports
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Reports, 17, 10, pp. 2572-2583
Cell reports, 17(10), 2572-2583. CELL PRESS
Cell Reports
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Digital.CSIC. Repositorio Institucional del CSIC
instname
Summary Fungal infections are major causes of morbidity and mortality, especially in immunocompromised individuals. The innate immune system senses fungal pathogens through Syk-coupled C-type lectin receptors (CLRs), which signal through the conserve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986764f8fabb157c6fa01f62fa0856bc
http://hdl.handle.net/2066/171927
http://hdl.handle.net/2066/171927
Autor:
Thomas Seeholzer, Juergen Ruland, Michael Grau, Christina Scheel, Peter Lenz, Georg Lenz, Miriam Bognar, Stefanie M. Hauck, M Vincendeau, Jelena R. Linnemann, Tabea Erdmann, Daniel Krappmann, German Ott
Publikováno v:
Oncogene 35, 4269-4281 (2016)
Oncogene
Oncogene
Constitutive activation of the antiapoptotic nuclear factor-κB (NF-κB) signaling pathway is a hallmark of the activated B-cell-like (ABC) subtype of diffuse large B-cell lymphomas (DLBCL). Recurrent oncogenic mutations are found in the scaffold pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760cd135c6e1c934acb66c67665c77e8
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=47705
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=47705
Autor:
Henning Walczak, Ueli Nachbur, James A Rickard, Monica Yabal, Mischa Kastirr, W. Wei-Lynn Wong, Niels Mailand, Simon Bekker-Jensen, Juergen Ruland, Christian Peschel, Philipp J. Jost, Andreas Strasser, John Silke, Thomas Kaufmann, Rune Busk Damgaard, Eva Rieser, Berthe Katrine Fiil, Aleksandra Bankovacki, Mads Gyrd-Hansen
Publikováno v:
Molecular cell
Mol. Cell 46, 746-758 (2012)
Mol. Cell 46, 746-758 (2012)
Nucleotide-binding and oligomerization domain (NOD)-like receptors constitute a first line of defense against invading bacteria. X-linked Inhibitor of Apoptosis (XIAP) is implicated in the control of bacterial infections, and mutations in XIAP are ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4db7c951ec970f32367550e51266f6
https://doi.org/10.1016/j.molcel.2012.04.014
https://doi.org/10.1016/j.molcel.2012.04.014
Autor:
Silvia Manzanero, Peter Henrik Andersen, Gordon D. Brown, Kelly J Hitchens, Roland Lang, Hanne Schoenen, Barbara Bodendorfer, Falk Nimmerjahn, Else Marie Agger, Kerstin Werninghaus, Christine A. Wells, Steffen Stenger, Juergen Ruland
Publikováno v:
The Journal of Immunology; Vol 184
The Journal of Immunology
The Journal of Immunology
The mycobacterial cord factor trehalose-6,6-dimycolate (TDM) and its synthetic analog trehalose-6,6-dibehenate (TDB) are potent adjuvants for Th1/Th17 vaccination that activate Syk-Card9 signaling in APCs. In this study, we have further investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1829321882caa9dda207dee517b7ca6d
Autor:
Juergen Ruland, Tim Sparwasser, Ichiro Taniuchi, Heinz Fehrenbach, Ali Oender Yildirim, Farahnaz Hatam, Stefan Ehlers, Cornelia Fessler, Johannes Stephani, Kerstin Walter, Norbert Reiling, Hermann Wagner, Martin Schaefer
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(10)
Dendritic cell (DC)-specific intercellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN: CD209) is a C-type lectin that binds ICAM-2,3 and various pathogens such as HIV, helicobacter, and mycobacteria. It has been suggested that Mycobacterium tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8956a621aa14f4dc2f0c04da511692c
https://pubmed.ncbi.nlm.nih.gov/18453604
https://pubmed.ncbi.nlm.nih.gov/18453604
Autor:
Uta Ferch, Christian Peschel, Olaf Gross, Tak W. Mak, Stephanie Weiss, Juergen Ruland, Philipp J. Jost, Stephanie Leeder
Publikováno v:
ResearcherID
Development of immature T cells in the thymus requires signals through the clonotypic T cell receptor (TCR). Thymocytes expressing a functionally inactive or autoreactive TCR are deleted via apoptosis (negative selection). Thymocytes expressing a fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe79e69b8412a9fc6ac9098433b746af
https://doi.org/10.1182/blood.v106.11.3323.3323
https://doi.org/10.1182/blood.v106.11.3323.3323