Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Juergen Ripperger"'
Circadian rhythms are self-sustained physiological changes that drive rhythmicity within the 24-hours cycles. Posttranslational modifications (PMTs), such as protein phosphorylation, acetylation, sumoylation, and ubiquitination, are biochemical proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f1411215a931ca0475f61fae485b5a0
https://doi.org/10.1101/2021.10.01.462714
https://doi.org/10.1101/2021.10.01.462714
Autor:
Giovanni Solinas, Juergen Ripperger, Alessandro Provenzani, Jean-Pierre Montani, Ludovic Breasson, Fabio Zani, Urs Albrecht, Barbara Becattini, Ana Vukolic
Publikováno v:
Molecular Metabolism
Molecular metabolism
Molecular metabolism
The interplay between hepatic glycogen metabolism and blood glucose levels is a paradigm of the rhythmic nature of metabolic homeostasis. Here we show that mice lacking a functional PER2 protein (Per2 (Brdm1) ) display reduced fasting glycemia, alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1dcea26634960b56790ee8379e1c6a2
Autor:
Juergen Ripperger, Martha Merrow
Publikováno v:
FEBS letters
In mammals, higher order chromatin structures are critical for downsizing the genome (packaging) so that the nucleus can be small. The adjustable density of chromatin also regulates gene expression, thus this post-genetic molecular mechanism is one o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d5b12edf71b46eca5e442b3170e037
Autor:
Sebastian Kadener, Ueli Schibler, Francis Vilbois, Juergen Ripperger, Michael Rosbash, Fabienne Fleury-Olela, Steven A. Brown
Publikováno v:
Science. 308:693-696
The clock proteins PERIOD1 (PER1) and PERIOD2 (PER2) play essential roles in a negative transcriptional feedback loop that generates circadian rhythms in mammalian cells. We identified two PER1-associated factors, NONO and WDR5, that modulate PER act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada2fdc6ccc8a15491b0e4908c57d552
https://doi.org/10.1126/science.1107373
https://doi.org/10.1126/science.1107373
Autor:
Yanping Wang, Meir Wetzler, Richard A. Van Etten, Heinz Baumann, Tomek Kordula, Juergen Ripperger, David Samols, G H Fey
Publikováno v:
Hepatology. 30:682-697
As part of systemic inflammatory reactions, interleukin 6 (IL-6) induces acute phase protein (APP) genes through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway. Epidermal growth factor (EGF), which contributes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd77a35fbcfe504f7a2afa8601ca7d9
https://doi.org/10.1002/hep.510300318
https://doi.org/10.1002/hep.510300318
Publikováno v:
Journal of Biological Chemistry. 274:7793-7802
Interleukin (IL)-6 is a major regulator of hepatic acute-phase plasma protein (APP) genes. The membrane-proximal 133-amino acid cytoplasmic domain of glycoprotein (gp) 130, containing one copy of the Box3 motif, is sufficient to transmit a productive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c2e78d45f70dd6b8792dd6886ec397
https://doi.org/10.1074/jbc.274.12.7793
https://doi.org/10.1074/jbc.274.12.7793
Publikováno v:
Annals of the New York Academy of Sciences. 762:502-504
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69cf1455e89adfe2a48d68b5ed75145b
https://doi.org/10.1111/j.1749-6632.1995.tb32382.x
https://doi.org/10.1111/j.1749-6632.1995.tb32382.x
Publikováno v:
Annals of the New York Academy of Sciences. 762:459-461
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14361b67e53642cfd8ec37e4b4f9af33
https://doi.org/10.1111/j.1749-6632.1995.tb32367.x
https://doi.org/10.1111/j.1749-6632.1995.tb32367.x
Autor:
Nelson D. Horseman, Heinz Baumann, K. K. Morella, Susana P. Campos, Juergen Ripperger, Chun-Fai Lai, David P. Gearing, Yanping Wang, G H Fey
Publikováno v:
Journal of Biological Chemistry. 270:23254-23257
Transient transfection of expression vectors for various members of the hematopoietin receptor family and STAT proteins into COS-1 cells indicated that each receptor was capable of stimulating the DNA binding activity of STAT1, STAT3, and STAT5B. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8a091cee4382e0c7555e8a499e9a1e
https://doi.org/10.1074/jbc.270.40.23254
https://doi.org/10.1074/jbc.270.40.23254
Autor:
Heinz Baumann, Chun-Fai Lai, K. K. Morella, Juergen Ripperger, Georg H. Fey, Susana P. Campos, Yanping Wang, David P. Gearing
Publikováno v:
Blood. 86:1671-1679
To determine the specificity of signal transducer and activator of transcription (STAT) protein activation by box 3 motif-deficient hematopoietin receptors, expression vectors encoding the receptors for growth hormone, interleukin-3 (IL-3), and IL-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e390dc4cab37be0f3fc2b029b8bf0f36
https://doi.org/10.1182/blood.v86.5.1671.bloodjournal8651671
https://doi.org/10.1182/blood.v86.5.1671.bloodjournal8651671