Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Juergen M. Schanzer"'
Publikováno v:
Journal of Immunotherapy. 29:477-488
Cytokine targeting to tumor-associated antigens via antibody cytokine fusion proteins has demonstrated potent antitumor activity in numerous animal models and has led to the clinical development of 2 antibody-interleukin-2 (IL-2) fusion proteins. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71b5819961ca0431ae81cec43aeb079
https://doi.org/10.1097/01.cji.0000210080.60178.fd
https://doi.org/10.1097/01.cji.0000210080.60178.fd
Autor:
and Juergen M. Schanzer, James B. Wiesner, Jay DaRe, Joseph J. Kopcho, Mark D. Erion, Angelo J. Castellino, Bheemarao G. Ugarkar
Publikováno v:
Journal of Medicinal Chemistry. 43:2883-2893
Adenosine receptor agonists produce a wide variety of therapeutically useful pharmacologies. However, to date they have failed to undergo successful clinical development due to dose-limiting side effects. Adenosine kinase inhibitors (AKIs) represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3f55e87ad3ee4daefc2927c4c517af
https://doi.org/10.1021/jm000024g
https://doi.org/10.1021/jm000024g
Publikováno v:
Cancer immunity. 6
Pro-inflammatory cytokines regulate the growth, differentiation, and activation of immune cells and can play a role in antitumor responses. GM-CSF and IL-2 induce tumor rejection in animal models when expressed by tumor cells, and IL-2 is used for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::426f6b39a25b3f58f6c10f44edb767a0
https://pubmed.ncbi.nlm.nih.gov/16483188
https://pubmed.ncbi.nlm.nih.gov/16483188
Autor:
Bheemarao G. Ugarkar, Angelo J. Castellino, Jay M. DaRe, Joseph J. Kopcho, James B. Wiesner, Juergen M. Schanzer, Mark D. Erion
Publikováno v:
Journal of medicinal chemistry. 43(15)
In the preceding article (Ugarkar et al. J. Med. Chem. 2000, 43) we reported that analogues of tubercidin are potent adenosine kinase (AK) inhibitors with antiseizure activity in the rat maximum electroshock (MES) model. Despite the discovery of seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b184bff86ca2e47f89d872d18dd41188
https://pubmed.ncbi.nlm.nih.gov/10956197
https://pubmed.ncbi.nlm.nih.gov/10956197