Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Juergen Kast"'
Autor:
Jukka Westermarck, William C. Hahn, Hannu Haapasalo, Juergen Kast, Shujun Lin, Kirsi Ketola, Olayinka Raheem, Kaisa Teittinen, Melissa E. Hector, Anna A. Sablina, Sari Vanhatupa, Melissa R. Junttila, Pietri Puustinen
Extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase pathway activity is regulated by the antagonist function of activating kinases and inactivating protein phosphatases. Sustained ERK pathway activity is commonly observed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3118af823a771241764483ca2ae7d791
https://doi.org/10.1158/0008-5472.c.6499386.v1
https://doi.org/10.1158/0008-5472.c.6499386.v1
Autor:
Jukka Westermarck, William C. Hahn, Hannu Haapasalo, Juergen Kast, Shujun Lin, Kirsi Ketola, Olayinka Raheem, Kaisa Teittinen, Melissa E. Hector, Anna A. Sablina, Sari Vanhatupa, Melissa R. Junttila, Pietri Puustinen
Supplementary Tables 1-3, Figures 1-6 from PME-1 Protects Extracellular Signal-Regulated Kinase Pathway Activity from Protein Phosphatase 2A–Mediated Inactivation in Human Malignant Glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae289e1f223410633bb3ffd4981a677e
https://doi.org/10.1158/0008-5472.22379901
https://doi.org/10.1158/0008-5472.22379901
Publikováno v:
Journal of Proteome Research. 15:4221-4233
Physiological stimuli such as thrombin, or pathological stimuli such as lysophosphatidic acid (LPA), activate platelets. The activated platelets bind to monocytes through P-selectin–PSGL-1 interactions but also release the contents of their granule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::571271bf3940a0f0353272c84c44099a
https://doi.org/10.1021/acs.jproteome.6b00212
https://doi.org/10.1021/acs.jproteome.6b00212
Autor:
Ru Li, Kate Liu, Shujun Lin, Honghui Jiang, Jason C. Rogalski, Chengcheng Zhang, Juergen Kast
Publikováno v:
Journal of Proteome Research. 14:967-976
Small GTPases are a family of key signaling molecules that are ubiquitously expressed in various types of cells. Their activity is often analyzed by western blot, which is limited by its multiplexing capability, the quality of isoform-specific antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23da88fc5c57d8d4d228daa25edb826e
https://doi.org/10.1021/pr501010v
https://doi.org/10.1021/pr501010v
Autor:
Christopher M. Overall, K.W.M. Siu, M. Mansoor, Juergen Kast, Leonard J. Foster, Paul Keown, Christoph H. Borchers, A. Scherer, William H. Hildebrand, T.A. Binkowski
Publikováno v:
Journal of Proteomics. 100:60-67
The Human Proteome Project (HPP) is designed to generate a comprehensive map of the protein-based molecular architecture of the human body, to provide a resource to help elucidate biological and molecular function, and to advance diagnosis and treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60af7196b4fafd6de6a9c8600825a08a
https://doi.org/10.1016/j.jprot.2013.08.001
https://doi.org/10.1016/j.jprot.2013.08.001
Publikováno v:
Journal of proteome research. 15(12)
Physiological stimuli such as thrombin, or pathological stimuli such as lysophosphatidic acid (LPA), activate platelets. The activated platelets bind to monocytes through P-selectin-PSGL-1 interactions but also release the contents of their granules,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c3b59536de980d1015ce35af4b3a7e8
https://pubmed.ncbi.nlm.nih.gov/27690452
https://pubmed.ncbi.nlm.nih.gov/27690452
Autor:
Juergen Kast
The immunoproteasome plays a key role in generation of HLA peptides for T cell-mediated immunity. Integrative genomic and proteomic analysis of non-small cell lung carcinoma (NSCLC) cell lines revealed significantly reduced expression of immunoprotea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa4f14346a01d5fe76739c1c52d394f
https://europepmc.org/articles/PMC5059315/
https://europepmc.org/articles/PMC5059315/
Publikováno v:
Expert Review of Proteomics. 9:281-291
Despite the rapid growth of postgenomic data and fast-paced technology advancement, drug discovery is still a lengthy and difficult process. More effective drug design requires a better understanding of the interaction between drug candidates and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8894532abd0e6e714d78cf34add6bb4
https://doi.org/10.1586/epr.12.22
https://doi.org/10.1586/epr.12.22
Autor:
Juergen Kast
Publikováno v:
Expert Review of Proteomics. 8:149-152
The regulation of protein abundance by microRNA (miRNA)-mediated repression of mRNA translation is a rapidly growing area of interest in biochemical research. In animal cells, the miRNA seed sequence does not perfectly match that of the mRNA it targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6831522efb8e2cf39ada33c58d59082f
https://doi.org/10.1586/epr.11.18
https://doi.org/10.1586/epr.11.18
Autor:
Ronald C. Beavis, Chengcheng Zhang, Daniel M. Evans, Cordula Klockenbusch, Juergen Kast, Jason C. Rogalski
Publikováno v:
Journal of Proteome Research. 10:656-668
Experiments to probe for protein-protein interactions are the focus of functional proteomic studies, thus proteomic data repositories are increasingly likely to contain a large cross-section of such information. Here, we use the Global Proteome Machi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cef997116cd10383118cb44a5ec5225
https://doi.org/10.1021/pr1008652
https://doi.org/10.1021/pr1008652