Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Juergen Hellmann"'
Autor:
Sven Jaeckel, Annika Hansen, Nina Glaser, Sigrid Johannes, Willem Sloot, Valentina Lai, Juergen Hellmann, Anja Knippel, Manuela Onidi
Publikováno v:
Toxicology and applied pharmacology. 429
M3258 is the first selective inhibitor of the immunoproteasome subunit LMP7 (Large multifunctional protease 7) in early clinical development with the potential to improve therapeutic utility in patients of multiple myeloma (MM) or other hematological
Autor:
Enrico Vigna, Manuela Onidi, Juergen Hellmann, Anja Knippel, Andrea Paoletti, Ping Yu, Christina Esdar
Publikováno v:
Toxicology and applied pharmacology. 406
Blocking Fibroblast Growth Factor Receptor 1 (FGFR1) is an attractive therapeutic option for treatment of cancer subtypes with amplification and over-expression of FGFR1. Selective targeting of FGFR1 can be achieved using an antibody-based approach,
Autor:
Hiroshi Satoh, Thomas J. Rosol, Takuji Tanaka, Zbigniew Wojcinski, Marc Bruder, Frédéric Schorsch, Sundeep Chandra, Mark G. Mense, Emmanuelle Balme, Takahito Kambara, Christian Landes, Mark J. Hoenerhoff, Annamaria Brändli-Baiocco, Barbara Lenz, Susanne Rittinghausen, Frank Seeliger, Juergen Hellmann, Minoru Tsuchitani
Publikováno v:
Journal of Toxicologic Pathology
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) Project (www.toxpath.org/inhand.asp) is a joint initiative among the Societies of Toxicological Pathology from Europe (ESTP), Great Britain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e39013474d798a427cb4d462794148
https://publica.fraunhofer.de/handle/publica/254258
https://publica.fraunhofer.de/handle/publica/254258
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 99(1)
Drug-induced hepatotoxicity is a major issue for drug development, and toxicogenomics has the potential to predict toxicity during early toxicity screening. A bead-based Illumina oligonucleotide microarray containing 550 liver specific genes has been
Autor:
Juergen Hellmann, Yvonne Walter, Carina Ittrich, Peter Juergen Kramer, Suse Beyer, Michaela Kroeger, Annette Kopp-Schneider
Publikováno v:
Journal of proteome research. 5(2)
A common animal model of chemical hepatocarcinogenesis was used to demonstrate the potential identification of carcinogenicity related protein signatures/biomarkers. Therefore, an animal study in which rats were treated with the known liver carcinoge
Publikováno v:
Toxicological Sciences; Sep2007, Vol. 99 Issue 1, p289-289, 1p
Akademický článek
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Publikováno v:
Risk Assessment of Phytochemicals in Food; 2010, p160-271, 112p
Criminal law has struggled to keep pace with developments in psychiatry, both in substantive and procedural terms, and it is widely recognised that increased inter-disciplinary discussion of mental condition defences is required in order to address t
Autor:
Deutscher Bühnenverein
Die 76. Ausgabe der Werkstatistik des Deutschen Bühnenvereins beruht auf den Daten zu Werken und Inszenierungen samt Aufführungs- und Zuschauerzahlen. 437 Theater aus Deutschland, Österreich und der Schweiz haben ihre Zahlen der Redaktion der DEUT