Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Juergen H Nett"'
Autor:
Michael E Brown, Daniel Bedinger, Asparouh Lilov, Palaniswami Rathanaswami, Maximiliano Vásquez, Stéphanie Durand, Ian Wallace-Moyer, Lihui Zhong, Juergen H Nett, Irina Burnina, Isabelle Caffry, Heather Lynaugh, Melanie Sinclair, Tingwan Sun, John Bukowski, Yingda Xu, Yasmina Noubia Abdiche
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229206 (2020)
Here we describe an industry-wide collaboration aimed at assessing the binding properties of a comprehensive panel of monoclonal antibodies (mAbs) against programmed cell death protein 1 (PD-1), an important checkpoint protein in cancer immunotherapy
Externí odkaz:
https://doaj.org/article/fc8fd2aadbea4beb830fe69ba9587bcc
Autor:
Juergen H Nett, W James Cook, Ming-Tang Chen, Robert C Davidson, Piotr Bobrowicz, Warren Kett, Elena Brevnova, Thomas I Potgieter, Mark T Mellon, Bianka Prinz, Byung-Kwon Choi, Dongxing Zha, Irina Burnina, John T Bukowski, Min Du, Stefan Wildt, Stephen R Hamilton
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68325 (2013)
The methylotrophic yeast, Pichiapastoris, is an important organism used for the production of therapeutic proteins. However, the presence of fungal-like glycans, either N-linked or O-linked, can elicit an immune response or enable the expressed prote
Externí odkaz:
https://doaj.org/article/430da7bedc8648048bd5e05cd1244467
Autor:
Anna Z. Wec, Daniel Wrapp, Andrew S. Herbert, Daniel Maurer, Denise Haslwanter, Mrunal Sakharkar, Rohit K. Jangra, M. Eugenia Dieterle, Asparouh Lilov, Deli Huang, Longping V. Tse, Nicole V. Johnson, Ching-Lin Hsieh, Nianshuang Wang, Juergen H. Nett, Elizabeth Champney, Irina Burnina, Michael Brown, Shu Lin, Melanie Sinclair, Carl Johnson, Sarat Pudi, Robert Bortz, Ariel S. Wirchnianski, Ethan Laudermilch, Catalina Florez, J. Maximilian Fels, Cecilia M. O’Brien, Barney S. Graham, David Nemazee, Dennis R. Burton, Ralph S. Baric, James E. Voss, Kartik Chandran, John M. Dye, Jason S. McLellan, Laura M. Walker
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 2
article-version (status) pre
article-version (number) 2
Broadly protective vaccines against known and pre-emergent coronaviruses are urgently needed. Critical to their development is a deeper understanding of cross-neutralizing antibody responses induced by natural human coronavirus (HCoV) infections. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c228fd092ccaf8df50d53fad057ba17d
https://pubmed.ncbi.nlm.nih.gov/32511337
https://pubmed.ncbi.nlm.nih.gov/32511337
Autor:
Juergen H. Nett, Terrance A. Stadheim, Huijuan Li, Min Du, Piotr Bobrowicz, Daniel Hopkins, Nathan J Sharkey, John Bukowski, W. James Cook, Sujatha Gomathinayagam, Irina Burnina, Stephen R. Hamilton, Shaina Schwartz, Stefan Wildt
Publikováno v:
Glycobiology. 23:1192-1203
The methylotrophic yeast, Pichia pastoris, is an important organism used for the production of therapeutic proteins. Previously, we have reported the glycoengineering of this organism to produce human-like N-linked glycans but up to now no one has ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef85cbf2997467f77dbc6ad086fca73c
https://doi.org/10.1093/glycob/cwt056
https://doi.org/10.1093/glycob/cwt056
Autor:
Sujatha Gomathinayagam, Nathan Sharkey, Peter M. Gray, Adam Nylen, Min Du, Thomas I. Potgieter, Seemab S. Shaikh, Raymond Evers, Terrance A. Stadheim, Robert C. Davidson, Russell B. Lingham, Julie A. DeMartino, Gavin C. Barnard, Daniel Hopkins, Muralidhar R. Mallem, Natarajan Sethuraman, Juergen H. Nett, Victoria Copeland, Thomas O. Linden, Marc d’Anjou, Yan Li, Liming Liu, Teresa Mitchell, Stephen R. Hamilton, Bing Gong, Denise M. Visco, Gail Forrest, Huijuan Li, Stefan Wildt
Publikováno v:
Journal of Biotechnology. 157:198-206
Pichia pastoris is a methylotropic yeast that has gained great importance as an organism for protein expression in recent years. Here, we report the expression of recombinant human erythropoietin (rhEPO) in glycoengineered P. pastoris. We show that g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5a467004a7cc4428d021a502528910
https://doi.org/10.1016/j.jbiotec.2011.11.002
https://doi.org/10.1016/j.jbiotec.2011.11.002
Publikováno v:
Bioengineered. 3:32-37
The methylotropic yeast Pichia pastoris has been used for more than two decades to successfully produce a large number of recombinant proteins. Currently, a wide variety of auxotrophic and drug based selection markers are employed to screen for clone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b937a1358c6cf3706b3cf329dcc31d
https://doi.org/10.4161/bbug.3.1.17936
https://doi.org/10.4161/bbug.3.1.17936
Autor:
Seemab S. Shaikh, Bianka Prinz, Juergen H. Nett, Adam Nylen, Fang Li, Alissa M. Rittenhour, Angela Kull, Irina Burnina, Nathan Sharkey, Teresa Mitchell, Natarajan Sethuraman, Thomas I. Potgieter, Terrance A. Stadheim, Dongxing Zha, Piotr Bobrowicz, Heather Lynaugh, Gavin C. Barnard, Youwei Jiang, Sandra Rios
Publikováno v:
Journal of Industrial Microbiology & Biotechnology. 37:961-971
The methylotrophic yeast Pichia pastoris has recently been engineered to express therapeutic glycoproteins with uniform human N-glycans at high titers. In contrast to the current art where producing therapeutic proteins in mammalian cell lines yields
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bac6c25035d40fbff8195c96fa5cfaa
https://doi.org/10.1007/s10295-010-0746-1
https://doi.org/10.1007/s10295-010-0746-1
Autor:
Thomas I. Potgieter, W. James Cook, Warren Kett, Stephen R. Hamilton, Byung-Kwon Choi, Robert C. Davidson, Irina Burnina, Stefan Wildt, Ming-Tang Chen, Mark Mellon, Piotr Bobrowicz, Dongxing Zha, Elena E. Brevnova, John Bukowski, Bianka Prinz, Min Du, Juergen H. Nett
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e68325 (2013)
PLoS ONE, Vol 8, Iss 7, p e68325 (2013)
The methylotrophic yeast, Pichia pastoris , is an important organism used for the production of therapeutic proteins. However, the presence of fungal-like glycans, either N-linked or O-linked, can elicit an immune response or enable the expressed pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c6f2bc9b58191f4ae0439504e8399b
https://pubmed.ncbi.nlm.nih.gov/23840891
https://pubmed.ncbi.nlm.nih.gov/23840891
Autor:
Sujatha Gomathinayagam, Huijuan Li, Juergen H. Nett, Nathan J Sharkey, Min Du, Khanita Karaveg, Stephen R. Hamilton, Terrance A. Stadheim, Alissa M. Rittenhour, Teresa Mitchell, Erik Hoyt, Daniel Hopkins
Publikováno v:
Glycobiology. 21(12)
The methylotrophic yeast, Pichia pastoris, is an important organism used for the production of therapeutic proteins. However, the presence of fungal-like glycans, such as those containing β-mannose (Man) linkages, can elicit an immune response or bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff41c0f48463c1ca0ebb03dcbd91ce58
https://pubmed.ncbi.nlm.nih.gov/21840970
https://pubmed.ncbi.nlm.nih.gov/21840970
Autor:
Juergen H. Nett
Publikováno v:
Therapeutic Monoclonal Antibodies: From Bench to Clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4743e2a2e40e0218eac86a2b844b1ddb
https://doi.org/10.1002/9780470485408.ch26
https://doi.org/10.1002/9780470485408.ch26
