Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Juergen G. Okun"'
Autor:
Ana Cecilia Mestre Citrinovitz, Jana Hauke, Julia Jauckus, Claus-Dieter Langhans, Kathrin Schwarz, Markus Zorn, Thomas Strowitzki, Juergen G. Okun, Ariane Germeyer
Publikováno v:
Journal of assisted reproduction and genetics. 39(12)
The differentiation of endometrial stromal cells, named decidualization, is essential for the proper formation of the materno-fetal interphase. One important feature of decidualization is the increased glucose consumption and its utilization by endom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a49ab3bb01907954bec223f5a7cee0
https://pubmed.ncbi.nlm.nih.gov/36308613
https://pubmed.ncbi.nlm.nih.gov/36308613
Autor:
ALBA SULAJ, STEFAN KOPF, EKATERINA V. RAUCHHAUPT, ELISABETH KLIEMANK, MAIK BRUNE, ZOLTAN KENDER, HANNELORE BARTL, FABIOLA GARCIA-CORTIZO, KATARINA KLEPAC, ZHE HAN, VARUN KUMAR, VALTER LONGO, AURELIO TELEMAN, JUERGEN G. OKUN, JAKOB MORGENSTERN, THOMAS H. FLEMING, JULIA M. SZENDROEDI, STEPHAN HERZIG
Publikováno v:
Diabetes. 71
Aim: To assess whether periodic fasting reduces albuminuria and activates nephropathy-driven pathways in patients with type 2 diabetes and diabetic nephropathy. Methods: Forty patients with type 2 diabetes (HbA1c 7.8±0.2% [62.1±2.3 mmol/mol]) and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2314663768dfd34001ce4f9ed6d639b4
https://doi.org/10.2337/db22-389-p
https://doi.org/10.2337/db22-389-p
Autor:
Revathi Sekar, Karsten Motzler, Yun Kwon, Aaron Novikoff, Julia Jülg, Bahar Najafi, Surui Wang, Anna-Luisa Warnke, Susanne Seitz, Daniela Hass, Sofiya Gancheva, Sabine Kahl, Bin Yang, Brian Finan, Kathrin Schwarz, Juergen G. Okun, Michael Roden, Matthias Blüher, Timo D. Müller, Natalie Krahmer, Christian Behrends, Oliver Plettenburg, Marta Miaczynska, Stephan Herzig, Anja Zeigerer
Publikováno v:
Cell metabolism 34 (2022), Nr. 11
Cell metabolism
Cell Metab. 34, 1824-1842.e9 (2022)
Cell metabolism
Cell Metab. 34, 1824-1842.e9 (2022)
During mammalian energy homeostasis, the glucagon receptor (Gcgr) plays a key role in regulating both glucose and lipid metabolisms. However, the mechanisms by which these distinct signaling arms are differentially regulated remain poorly understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f16941faa007e9843f2d5c89c05a11b
https://doi.org/10.1016/j.cmet.2022.10.013
https://doi.org/10.1016/j.cmet.2022.10.013
Autor:
Clothilde Roux, Rudolf Griss, Sebastian Fabritz, Juergen G. Okun, Qiuliyang Yu, Dorothea Haas, Pierre-Alain Binz, Julien Hiblot, Lin Xue, Kai Johnsson
Publikováno v:
Science
A protein designed to sense metabolites Many diseases cause characteristic changes in blood metabolites. Yu et al. describe a paper-based assay in which a chosen metabolite can be oxidized to generate reduced nicotinamide adenine dinucleotide phospha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216b3b8035c23f3cc1dfdf20d6c6b3b3
https://doi.org/10.1126/science.aat7992
https://doi.org/10.1126/science.aat7992
Autor:
Georg F. Hoffmann, Daniel Hübschmann, Thomas Bruckner, Ansgar Schulz, Laura Tagliaferri, Susanna Esposito, Margit Happich, Carsten Speckmann, Joachim B. Kunz, Andreas E. Kulozik, Martina U. Muckenthaler, Judit Kappe, Juergen G. Okun
The prognosis of children with severe combined immunodeficiency (SCID) depends on a presymptomatic diagnosis and early treatment before complications occur. We established and tested a simplified, practical and economic newborn screening method based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c7df39a332a34635dce20df63d28cb
http://hdl.handle.net/11391/1417981
http://hdl.handle.net/11391/1417981
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1777:1276-1282
Accumulation of organic acids as well as their CoA and carnitine esters in tissues and body fluids is a common finding in organic acidurias, beta-oxidation defects, Reye syndrome, and Jamaican vomiting sickness. Pathomechanistic approaches for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0db1c7e3d60ccae0760922e4d5dd23
https://doi.org/10.1016/j.bbabio.2008.05.447
https://doi.org/10.1016/j.bbabio.2008.05.447
Autor:
Richard I. Kelley, Heiko Runz, Bob Long, Johannes Zschocke, Janine Morgenthaler, Dorothea Haas, Georg F. Hoffmann, Felicitas Lacbawan, Maximilian Muenke, Juergen G. Okun, Sven F. Garbade
Publikováno v:
Journal of Medical Genetics. 44:298-305
Objective: Holoprosencephaly (HPE) is the most common structural malformation of the developing forebrain in humans. The etiology is heterogeneous and remains unexplained in approximately 75% of patients. Because perturbations of cholesterol homeosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b984fea6db6b3186e3cce1427a6f766
https://doi.org/10.1136/jmg.2006.047258
https://doi.org/10.1136/jmg.2006.047258
Autor:
Joél Smet, Arnaud Vanlander, Birgitte Wuyts, Boel De Paepe, Elien De Latter, Rudy Van Coster, Juergen G. Okun, Bert Vanheel, Peter De Paepe, Georges A. Dacremont, Annick de Jaeger, Philippe G. Jorens, Niels Van Regenmortel
Publikováno v:
Anesthesiology
Background: Propofol is a short-acting intravenous anesthetic agent. In rare conditions, a life-threatening complication known as propofol infusion syndrome can occur. The pathophysiologic mechanism is still unknown. Some studies suggested that propo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047d8df426209ab625185c62d093b03d
https://hdl.handle.net/10067/1255240151162165141
https://hdl.handle.net/10067/1255240151162165141
Autor:
Juergen G. Okun, Florian Kurschuss, Maren Paulsen, Theresa Schumacher, Wolfgang Wick, Philip Rosenstiel, Melanie Keil, Christoph Reinhardt, Jana K. Sonner, Michael Platten, Iris Oezen, Florian Wanke
Publikováno v:
Journal of Neuroimmunology. 275:156
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92005b23871baf3b301965d397708f0e
https://doi.org/10.1016/j.jneuroim.2014.08.418
https://doi.org/10.1016/j.jneuroim.2014.08.418
Autor:
Clarissa Gerhäuser, Jochen H. M. Prehn, Julia Strathmann, Juergen G. Okun, Sven W. Sauer, Karin Klimo
Publikováno v:
Cancer Prevention Research. 3:A59-A59
Xanthohumol (XN), a polyphenol from hops (Humulus lupulus L.), exerts a broad spectrum of cancer chemopreventive activities, including the induction of apoptosis in human cancer cell lines. We speculated that apoptosis induction involved pro-oxidant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa572cf08da860a29d8627d3f68a7c95
https://doi.org/10.1158/1940-6207.prev-09-a59
https://doi.org/10.1158/1940-6207.prev-09-a59