Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Juergen E. Gschwend"'
Autor:
Zhichao Tong, Anuja Sathe, Benedikt Ebner, Pan Qi, Christian Veltkamp, Juergen E. Gschwend, Per Sonne Holm, Roman Nawroth
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background CDK4/6 inhibitors are a promising treatment strategy in tumor therapy but are hampered by resistance mechanisms. This study was performed to reveal predictive markers, mechanisms of resistance and to develop rational combination t
Externí odkaz:
https://doaj.org/article/4ff9929e028c408e8f8a62695ccbcf33
STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy
Autor:
Sruthi V. Hindupur, Sebastian C. Schmid, Jana Annika Koch, Ahmed Youssef, Eva-Maria Baur, Dongbiao Wang, Thomas Horn, Julia Slotta-Huspenina, Juergen E. Gschwend, Per Sonne Holm, Roman Nawroth
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1106 (2020)
The JAK-STAT signalling pathway regulates cellular processes like cell division, cell death and immune regulation. Dysregulation has been identified in solid tumours and STAT3 activation is a marker for poor outcome. The aim of this study was to expl
Externí odkaz:
https://doaj.org/article/0fd94773816f4472bb90516173d2ccdf
Autor:
Rainer Kuefer, Felicitas Genze, Waltraud Zugmaier, Richard E. Hautmann, Ludwig Rinnab, Juergen E. Gschwend, Marina Angelmeier, Aidee Estrada, Berthold Buechele
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 3, Pp 246-253 (2007)
Butyrates and retinoids are promising antineoplastic agents. Here we analyzed effects of sodium butyrate and N-(4-hydroxyphenyl)-retinamide (4-HPR) on prostate cancer cells as monotherapy or in combination in vitro and in vivo. Sodium butyrate and 4-
Externí odkaz:
https://doaj.org/article/0937b29f58d5409880814f61d8b12d33
Autor:
Pamela L. Paris, Matthias D. Hofer, Giancarlo Albo, Rainer Kuefer, Juergen E. Gschwend, Richard E. Hautmann, Jane Fridyland, Jeffrey Simko, Peter R. Carroll, Mark A. Rubin, Colin Collins
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 12, Pp 1083-1089 (2006)
The progression of organ-confined prostate cancer to metastatic cancer is inevitably fatal. Consequently, identification of structural changes in the genome and associated transcriptional responses that drive this progression is critical to understan
Externí odkaz:
https://doaj.org/article/e1fec85f510942da9365346703b91f4d
Autor:
Simon KB Spohn, Nina-Sophie Schmidt-Hegemann, Juri Ruf, Michael Mix, Matthias Benndorf, Fabian Bamberg, Marcus R Makowski, Simon Kirste, Alexander Rühle, Jerome Nouvel, Tanja Sprave, Marco ME Vogel, Polina Galitsnaya, Juergen E Gschwend, Christian Gratzke, Christian Stief, Steffen Loeck, Alex Zwanenburg, Christian Trapp, Denise Bernhardt, Stephan G Nekolla, Minglun Li, Claus Belka, Stephanie E Combs, Matthias Eiber, Lena Unterrainer, Marcus Unterrainer, Peter Bartenstein, Anca L Grosu, Constantinos Zamboglou, Jan C Peeken
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging.
Purpose To develop a CT-based radiomic signature to predict biochemical recurrence (BCR) in prostate cancer patients after sRT guided by positron-emission tomography targeting prostate-specific membrane antigen (PSMA-PET). Material and methods Consec
Autor:
Enya Müller, Dr. Valentin H. Meissner, Prof. Martina Kron, Stefan Schiele, Helga Schulwitz, Prof. Juergen E. Gschwend, Prof. Kathleen Herkommer
Publikováno v:
The Journal of Sexual Medicine. 19:S79-S80
Autor:
Simon Spohn, Andrea Farolfi, Sarah Schandeler, Marco M.E. Vogel, Juri Ruf, Michael Mix, Simon Kirste, Francesco Ceci, Stefano Fanti, Helena Lanzafame, Francesca Serani, Christian Gratzke, August Sigle, Stephanie E. Combs, Denise Bernhardt, Juergen E. Gschwend, Josef A. Buchner, Christian Trapp, Claus Belka, Peter Bartenstein, Matthias Eiber, Stephan G. Nekolla, Kilian Schiller, Anca L. Grosu, Nina-Sophie Schmidt-Hegemann, Constantinos Zamboglou, Jan C. Peeken
Purpose: This study aims to evaluate the association of the maximum standardized uptake value (SUVmax) in positron-emission tomography targeting prostate-specific-membrane-antigen (PSMA-PET) prior to savage radiotherapy (sRT) on biochemical recurrenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a509b096c6af531c94f92ee3e982fce9
https://doi.org/10.21203/rs.3.rs-1615714/v1
https://doi.org/10.21203/rs.3.rs-1615714/v1
Autor:
Simon K. B. Spohn, Andrea Farolfi, Sarah Schandeler, Marco M. E. Vogel, Juri Ruf, Michael Mix, Simon Kirste, Francesco Ceci, Stefano Fanti, Helena Lanzafame, Francesca Serani, Christian Gratzke, August Sigle, Stephanie E. Combs, Denise Bernhardt, Juergen E. Gschwend, Josef A. Buchner, Christian Trapp, Claus Belka, Peter Bartenstein, Lena Unterrainer, Marcus Unterrainer, Matthias Eiber, Stephan G. Nekolla, Kilian Schiller, Anca L. Grosu, Nina-Sophie Schmidt-Hegemann, Constantinos Zamboglou, Jan C. Peeken
Publikováno v:
Eur. J. Nucl. Med. Mol. Imaging 50, 218-227 (2022)
Purpose This study aims to evaluate the association of the maximum standardized uptake value (SUVmax) in positron-emission tomography targeting prostate-specific membrane antigen (PSMA-PET) prior to salvage radiotherapy (sRT) on biochemical recurrenc
Autor:
Juergen E. Gschwend, Nathalie Garzon, Shilpa Gupta, Bradley Raybold, Mark Rutstein, Danny Liaw, Michiel S. van der Heijden, Gary D. Steinberg, Matthew D. Galsky, Guru Sonpavde, Mohammed Ibrahim, Andrea Necchi
Publikováno v:
Future oncology (London, England). 16(2):4359-4368
Immune checkpoint inhibitors have revolutionized the treatment of patients with metastatic urothelial carcinoma. In cisplatin-eligible muscle-invasive bladder cancer (MIBC), cisplatin-based neoadjuvant chemotherapy (NAC) before radical cystectomy imp
Autor:
Kathleen Herkommer, Thomas Amiel, Robert Tauber, Thomas Steuber, Gunhild von Amsberg, Christa Babst, Matthias Heck, Margitta Retz, Markus Graefen, Matthias Eiber, Lukas Lunger, Sophie Knipper, Juergen E. Gschwend, Tobias Maurer
Publikováno v:
Asian Journal of Urology, Vol 9, Iss 1, Pp 69-74 (2022)
Objective: Cytoreductive radical prostatectomy (cRP) has been proposed as local treatment option in metastatic hormone-sensitive prostate cancer (mHSPC) to prevent local complications and potentially improve oncological outcomes. In this study, we ex