Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Juergen, Loeffler"'
Autor:
Mario Cruciani, P. Lewis White, Rosemary A. Barnes, Juergen Loeffler, J. Peter Donnelly, Thomas R. Rogers, Werner J. Heinz, Adilia Warris, Charles Oliver Morton, Martina Lengerova, Lena Klingspor, Boualem Sendid, Deborah E. A. Lockhart
Publikováno v:
Journal of Fungi, Vol 9, Iss 10, p 967 (2023)
This overview of reviews (i.e., an umbrella review) is designed to reappraise the validity of systematic reviews (SRs) and meta-analyses related to the performance of Aspergillus PCR tests for the diagnosis of invasive aspergillosis in immunocompromi
Externí odkaz:
https://doaj.org/article/be635a4718ef4bc9a77c968c907ab0ee
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The COVID-19 pandemic has placed a huge strain on global healthcare and been a significant cause of increased morbidity and mortality, particularly in at-risk populations. This disease attacks the respiratory systems and causes significant immune dys
Externí odkaz:
https://doaj.org/article/daac7d1f0f254454a5d2aeb62d5d920e
Publikováno v:
Journal of Fungi, Vol 8, Iss 12, p 1307 (2022)
Invasive fungal disease (IFD) causes severe morbidity and mortality, and the number of IFD cases is increasing. Exposure to opportunistic fungal pathogens is inevitable, but not all patients with underlying diseases increasing susceptibility to IFD,
Externí odkaz:
https://doaj.org/article/dfc366db02bd449abde7bfd9a5bc62d0
Autor:
Lukas Page, Julia Wallstabe, Jasmin Lother, Maximilian Bauser, Olaf Kniemeyer, Lea Strobel, Vera Voltersen, Janka Teutschbein, Peter Hortschansky, Charles Oliver Morton, Axel A. Brakhage, Max Topp, Hermann Einsele, Sebastian Wurster, Juergen Loeffler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Aspergillus fumigatus causes life-threatening opportunistic infections in immunocompromised patients. As therapeutic outcomes of invasive aspergillosis (IA) are often unsatisfactory, the development of targeted immunotherapy remains an important goal
Externí odkaz:
https://doaj.org/article/207287c8a5c445f8b26ff8097c93cc97
Publikováno v:
Mycology, Vol 10, Iss 2, Pp 75-83 (2019)
This paper sought to address the prevalence of Mucorales in different indoor environments in Portugal. Environmental samples (183 in total) were collected at dwellings (n = 79) and workplaces (bakeries, swine farms, taxis, waste-sorting plants) (n =
Externí odkaz:
https://doaj.org/article/f70280657c5a4c04b4452c8959b328b1
Publikováno v:
BMC Immunology, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background The saprophytic fungus Aspergillus fumigatus reproduces by generation of conidia, which are spread by airflow throughout nature. Since humans are inhaling certain amounts of spores every day, the (innate) immune system is constant
Externí odkaz:
https://doaj.org/article/606ed6806f8442cdb0341219fffaa108
Autor:
Arun J. Sanyal, Patricia Lopez, Eric J. Lawitz, Kathryn J. Lucas, Juergen Loeffler, Won Kim, George B. B. Goh, Jee-Fu Huang, Carla Serra, Pietro Andreone, Yi-Cheng Chen, Stanley H. Hsia, Vlad Ratziu, Diego Aizenberg, Hiroshi Tobita, Aasim M. Sheikh, John M. Vierling, Yoon Jun Kim, Hideyuki Hyogo, Dean Tai, Zachary Goodman, Felicity Schaefer, Ian R. I. Carbarns, Sophie Lamle, Miljen Martic, Nikolai V. Naoumov, Clifford A. Brass
Publikováno v:
Nature Medicine. 29:392-400
The multimodal activities of farnesoid X receptor (FXR) agonists make this class an attractive option to treat nonalcoholic steatohepatitis. The safety and efficacy of tropifexor, an FXR agonist, in a randomized, multicenter, double-blind, three-part
Autor:
Bastian Seelbinder, Julia Wallstabe, Lothar Marischen, Esther Weiss, Sebastian Wurster, Lukas Page, Claudia Löffler, Lydia Bussemer, Anna-Lena Schmitt, Thomas Wolf, Jörg Linde, Luka Cicin-Sain, Jennifer Becker, Ulrich Kalinke, Jörg Vogel, Gianni Panagiotou, Hermann Einsele, Alexander J. Westermann, Sascha Schäuble, Juergen Loeffler
Publikováno v:
Cell Reports, Vol 33, Iss 7, Pp 108389- (2020)
Summary: High-throughput RNA sequencing (RNA-seq) is routinely applied to study diverse biological processes; however, when performed separately on interacting organisms, systemic noise intrinsic to RNA extraction, library preparation, and sequencing
Externí odkaz:
https://doaj.org/article/9574c6231e344604ad967349b3a8eede
Autor:
Tamara Zoran, Bastian Seelbinder, Philip Lewis White, Jessica Sarah Price, Sabrina Kraus, Oliver Kurzai, Joerg Linde, Antje Häder, Claudia Loeffler, Goetz Ulrich Grigoleit, Hermann Einsele, Gianni Panagiotou, Juergen Loeffler, Sascha Schäuble
Publikováno v:
Journal of Fungi, Vol 8, Iss 2, p 171 (2022)
Despite available diagnostic tests and recent advances, diagnosis of pulmonary invasive aspergillosis (IPA) remains challenging. We performed a longitudinal case-control pilot study to identify host-specific, novel, and immune-relevant molecular cand
Externí odkaz:
https://doaj.org/article/86fbb2e9ff97466fa51d8bb8feb3bb70
Autor:
Esther Weiss, Jan Schlegel, Ulrich Terpitz, Michael Weber, Jörg Linde, Anna-Lena Schmitt, Kerstin Hünniger, Lothar Marischen, Florian Gamon, Joachim Bauer, Claudia Löffler, Oliver Kurzai, Charles Oliver Morton, Markus Sauer, Hermann Einsele, Juergen Loeffler
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Delayed natural killer (NK) cell reconstitution after allogeneic stem cell transplantation (alloSCT) is associated with a higher risk of developing invasive aspergillosis. The interaction of NK cells with the human pathogen Aspergillus (A.) fumigatus
Externí odkaz:
https://doaj.org/article/c83d94d16f584d25a9f56cbbca05603d