Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Juergen, Fink"'
Autor:
Catherine Dabrowska, Lemonia Chatzeli, Roxana C. Mustata, Seungmin Han, Roberta Azzarelli, Daniel E. Stange, Eunmin Lee, Irina Pshenichnaya, Min Kyu Yum, Bon-Kyoung Koo, Jong Kyoung Kim, Frances J. England, Juergen Fink, Teodora Trendafilova, Anna Philpott, Szu-Hsien Sam Wu, Benjamin D. Simons, Joo-Hyeon Lee
Publikováno v:
Nature. 594:442-447
Interactions between tumour cells and the surrounding microenvironment contribute to tumour progression, metastasis and recurrence1–3. Although mosaic analyses in Drosophila have advanced our understanding of such interactions4,5, it has been diffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f20abc00ab9100625df072dac67bdbbf
https://doi.org/10.1038/s41586-021-03605-0
https://doi.org/10.1038/s41586-021-03605-0
Autor:
Ji-Hyun, Lee, Somi, Kim, Seungmin, Han, Jimin, Min, Brianna, Caldwell, Aileen-Diane, Bamford, Andreia Sofia Batista, Rocha, JinYoung, Park, Sieun, Lee, Szu-Hsien Sam, Wu, Heetak, Lee, Juergen, Fink, Sandra, Pilat-Carotta, Jihoon, Kim, Manon, Josserand, Réka, Szep-Bakonyi, Yohan, An, Young Seok, Ju, Anna, Philpott, Benjamin D, Simons, Daniel E, Stange, Eunyoung, Choi, Bon-Kyoung, Koo, Jong Kyoung, Kim
Publikováno v:
Cell stem cell. 29(5)
Adult stem cells constantly react to local changes to ensure tissue homeostasis. In the main body of the stomach, chief cells produce digestive enzymes; however, upon injury, they undergo rapid proliferation for prompt tissue regeneration. Here, we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95af1a7c7f1b3f1ae2151b3e4ed6790d
https://pubmed.ncbi.nlm.nih.gov/35523142
https://pubmed.ncbi.nlm.nih.gov/35523142
Autor:
Ji-Hyun Lee, Somi Kim, Seungmin Han, Jimin Min, Brianna Caldwell, Aileen-Diane Bamford, Andreia Sofia Batista Rocha, JinYoung Park, Sieun Lee, Szu-Hsien Sam Wu, Heetak Lee, Juergen Fink, Sandra Pilat-Carotta, Jihoon Kim, Manon Josserand, Réka Szep-Bakonyi, Yohan An, Young Seok Ju, Anna Philpott, Benjamin D. Simons, Daniel E. Stange, Eunyoung Choi, Bon-Kyoung Koo, Jong Kyoung Kim
Publikováno v:
Cell Stem Cell. 29:826-839.e9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56c2dbd5cd9376be082b2c9bc31bcbe1
https://doi.org/10.1016/j.stem.2022.04.001
https://doi.org/10.1016/j.stem.2022.04.001
Autor:
David G Kent, Juan Li, Hinal Tanna, Juergen Fink, Kristina Kirschner, Dean C Pask, Yvonne Silber, Tina L Hamilton, Rachel Sneade, Benjamin D Simons, Anthony R Green
Publikováno v:
PLoS Biology, Vol 11, Iss 6, p e1001576 (2013)
Recent descriptions of significant heterogeneity in normal stem cells and cancers have altered our understanding of tumorigenesis, emphasizing the need to understand how single stem cells are subverted to cause tumors. Human myeloproliferative neopla
Externí odkaz:
https://doaj.org/article/7dfd3a5ed19c436ab9d0cf6c7ee2e024
Autor:
Min Kyu Yum, Benjamin D. Simons, Ji-Hyun Lee, Jong Kyoung Kim, Lemonia Chatzeli, Ronald Naumann, Seungmin Han, Richard L. Mort, David J. Jörg, Onur Basak, Eunmin Lee, Sebastian R. Merker, Amanda Andersson-Rolf, Manon Josserand, Catherine Dabrowska, Bon-Kyoung Koo, Juergen Fink, Hans Clevers, Daniel E. Stange, Anna Philpott, Nobuo Sasaki, Teodora Trendafilova, Hyunki Kim
Publikováno v:
Cell Stem Cell, 25(3), 342-356.e7. Cell Press
Cell Stem Cell
Cell Stem Cell
Summary The gastric corpus epithelium is the thickest part of the gastrointestinal tract and is rapidly turned over. Several markers have been proposed for gastric corpus stem cells in both isthmus and base regions. However, the identity of isthmus s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b025d0b81133a41c24be731f2f6640
https://pure.knaw.nl/portal/en/publications/fb162bc7-17bc-464b-ab82-8fcf0b7699f8
https://pure.knaw.nl/portal/en/publications/fb162bc7-17bc-464b-ab82-8fcf0b7699f8
Autor:
William C. Skarnes, Sajith Perera, Roxana C. Mustata, Katie Tremble, José C. R. Silva, Tiago Grego, Katie Andrews, Jihoon Kim, Juergen Fink, Alessandra Merenda, Bon-Kyoung Koo, Amanda Andersson-Rolf
Publikováno v:
Nature methods
Loss-of-function studies are key for investigating gene function, and CRISPR technology has made genome editing widely accessible in model organisms and cells. However, conditional gene inactivation in diploid cells is still difficult to achieve. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549a5ba59c7d949d22411a908bcaca9e
https://doi.org/10.1038/nmeth.4156
https://doi.org/10.1038/nmeth.4156
Autor:
Mairi Shepherd, Dean C. Pask, Caroline A. Oedekoven, Anjana Rao, Juergen Fink, Anthony R. Green, Juan Li, David G. Kent, Nicola K. Wilson, Tina L. Hamilton, Jiangbing Li, Miriam Belmonte, Timm Schröder, Dirk Loeffler, Janine C. M. Prick, Berthold Göttgens
Recent advances in single-cell technologies have permitted the investigation of heterogeneous cell populations at previously unattainable resolution. Here we apply such approaches to resolve the molecular mechanisms driving disease in mouse hematopoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354e0bd77ab3f548f5b6a0719fa7b2a7
https://europepmc.org/articles/PMC6107881/
https://europepmc.org/articles/PMC6107881/
Autor:
Seungmin Han, Manon Josserand, Bon-Kyoung Koo, Min Kyu Yum, David J. Jörg, Hans Clevers, Benjamin D. Simons, Daniel E. Stange, Onur Basak, Hyunki Kim, Eunmin Lee, Richard L. Mort, Sebastian R. Merker, Amanda Andersson-Rolf, Nobuo Sasaki, Jong Kyoung Kim, Ji-Hyun Lee, Teodora Trendafilova, Catherine Dabrowska, Juergen Fink
Publikováno v:
SSRN Electronic Journal
The gastric corpus epithelium is the thickest part of the gastro-intestinal tract and is characterized by rapid tissue turnover. Several markers have been proposed for gastric corpus stem cells in both isthmus and base regions. However, the identity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80152bed3b508cd3c1fbe8f3cc5bd7e1
Publikováno v:
BMB Reports
Lineage tracing is a widely used method for understanding cellular dynamics in multicellular organisms during processes such as development, adult tissue maintenance, injury repair and tumorigenesis. Advances in tracing or tracking methods, from ligh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2344e8cc5dfc5e212e9f4cf1d1eb1fc5
https://doi.org/10.5483/bmbrep.2015.48.12.249
https://doi.org/10.5483/bmbrep.2015.48.12.249
Autor:
Juan Li, David G. Kent, Anna L. Godfrey, Anthony R. Green, Pentao Liu, Dean C. Pask, Juergen Fink, Jyoti Nangalia, Athar Aziz, Xiaodong Zhao, Harriet Manning, Cedric Ghevaert, Edwin Chen, Yvonne Silber, Rachel Sneade, Tina L. Hamilton, Kourosh Saeb-Parsy
Publikováno v:
Blood. 123:3139-3151
Genomic regions of acquired uniparental disomy (UPD) are common in malignancy and frequently harbor mutated oncogenes. Homozygosity for such gain-of-function mutations is thought to modulate tumor phenotype, but direct evidence has been elusive. Poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc0182ae9b198c7e8b60737a036bc21
https://doi.org/10.1182/blood-2013-06-510222
https://doi.org/10.1182/blood-2013-06-510222