Is High Prevalence of Echinococcus multilocularis in Wild and Domestic Animals Associated with Disease Incidence in Humans?

Autor: Bruno Gottstein, Francis Saucy, Peter Deplazes, Juerg Reichen, Georges Demierre, Andre Busato, Christian Zuercher, Paul Pugin

Publikováno v: Emerging Infectious Diseases, Vol 7, Iss 3, Pp 408-412 (2001)

We investigated a focus of highly endemic Echinococcus multilocularis infection to assess persistence of high endemicity in rural rodents, explore potential for parasite transmission to domestic carnivores, and assess (serologically) putative exposur

Externí odkaz: https://doaj.org/article/7cb37cdb54144ac397bba639ce079862

Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure

Autor: Milton Packer, John J.V. McMurray, Henry Krum, Wolfgang Kiowski, Barry M. Massie, Avi Caspi, Craig M. Pratt, Mark C. Petrie, David DeMets, Isaac Kobrin, Sebastien Roux, Karl Swedberg, Craig Pratt, Barry Massie, John McMurray, Eugene Connally, Mark Petrie, Susan Anderson, Jody Barnet, Robert Cody, Henry Dargie, Gary Francis, Barry Greenberg, Juerg Reichen, J. Karrasch, H. Krum, J. Horowitz, J. Amerena, A. Sindone, P. MacDonald, I. Jeffrey, I. Button, E. DeAngelis, R. Pacher, R. Davies, F. McAlister, P. Tanser, B. Sussex, G. Baumann, E. Fleck, H.-G. Olbrich, K. Werdan, H. Klein, F. Staffeld, A.M. Zeiher, C. Roediger, A. Caspi, A. Marmor, L. Reisin, Z. Vered, E. Klainman, N. Roguin, D. Tzivoni, D. David, B. Lewis, E. Abinader, M. Omary, Y. Rosenman, E. Kaluski, R.W. Breedveld, P.H. van der Burgh, P.H.J.M. Dunselman, H.J. Schaafsma, D.P. Hertzberger, N.J. Holwerda, J.A. Kragten, J. van Wijngaarden, J.L. Posma, S.A.M. Said, L.C. Slegers, R.M. Tjon Joe Gin, F.N. Wempe, J.C.L. Wesdorp, A.R. Willems, A.J.A.M. Withagen, J.M. Cornel, L.H.J. van Kempen, W. Kiowski, O. Bertel, T. Moccetti, J.J.V. McMurray, R.A. Greenbaum, P. Bennett, J. Swan, G. Davies, I. Findlay, B. Gould, S. Ball, P. Hubner, A. Lahiri, J. McLay, R. Northcote, S. Saltissi, I. Squire, J. Stephens, M. Stewart, G. Bridgen, J. Walsh, D.J. Webb, Z. Ansari, S. Baron, R. Bellinger, W. Bennet, D. Benvenuti, D. Dawley, L.C. Egbujiobi, I. Eisenstein, T. Little, A. Hertsberg, M. Greenspan, R.J. Grossman, P. Hanley, M. Jesrani, H. Kashou, R. Levites, R. Malik, B. Marmorstein, M. Schwartz, A. Nisar, R. Perelman, M.L. Schwarz, S. Sedlis, J. Srebro, M. Taveras, R. Weiss, P. Weitzman, G.K. Wetherley, M. El Shahawy, D. Kereiakes, L. Campos, G. Peterson, R.S. Small, W.R. Davis, M.-T. Olivari, W. Meengs, M. Koren, P. Slagona, S. Jennison, R. Hershberger, K.F. Browne, D.J. Farnham, S. Zelenkofske, C. Lawless, M. Nathan, T. Meyer, M. Kukin, H. Parekh, R. Berkowitz, J. Boehmer, S. Brozena, P. Dandona, G.W. Dec, V. DeQuattro, P. Fenster, M. Fowler, S. Ellaham, M. Geller, M. Gheorgiade, J. Ghali, S. Murali, S. Katz, C. Bott-Silverman, B. Singh, U. Thadani, G. Torre, J. Teerlink, T. Chandraratna, M. Kesselbrenner, A. Mukherjee, C. Che-Pin Tsai, K. Abbo, M. Goldberg, T. Smith, R.T. Martin

Publikováno v: JACC: Heart Failure. 5:317-326

Objectives The objective of this clinical trial was to evaluate the long-term effect of endothelin receptor antagonism with bosentan on the morbidity and mortality of patients with severe chronic heart failure. Background Endothelin may play a role i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb048a52ef9808b8c1bc2dbcf796ca66
https://doi.org/10.1016/j.jchf.2017.02.021

Herbal does not mean innocuous: Ten cases of severe hepatotoxicity associated with dietary supplements from Herbalife® products

Autor: Alain Schoepfer, Carl Oneta, Arthur Zimmermann, Antoinette Engel, Dominique H. Criblez, Urs A. Marbet, Juerg Reichen, Karin Fattinger

Publikováno v: Journal of hepatology

Background/Aims Herbal agents are popular and perceived as safe because they are supposedly ‘natural'. We report 10 cases of toxic hepatitis implicating Herbalife ® products. Methods To determine the prevalence and outcome of hepatotoxicity due to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0eb538c2639bfacdeb943b1d085a65b
https://doi.org/10.1016/j.jhep.2007.06.014

Oral imatinib treatment reduces early fibrogenesis but does not prevent progression in the long term

Autor: Nicolas Widmer, Markus Neef, Bertrand Rochat, M. Ledermann, Juerg Reichen, Vreni Schneider, H. Saegesser, Laurent A. Decosterd

Publikováno v: Journal of Hepatology. 44:167-175

Background/Aims: Transactivated hepatic stellate cells (HSCs) represent the key source of extra cellular matrix (ECM) in fibrotic liver. Imatinib, a potent inhibitor of the PDGF receptor tyrosine kinase, reduces HSC proliferation and fibrogenesis whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8222afb1499304f92082df438a1737d
https://doi.org/10.1016/j.jhep.2005.06.015

Endothelial, but not the inducible, nitric oxide synthase is detectable in normal and portal hypertensive rats

Autor: Lazar T. Sumanovski, Cornel Christian Sieber, Pierre-Yves Martin, Juerg Reichen, Daniel D'Orazio, Michael Stumm

Publikováno v: Liver. 22:441-450

BACKGROUND: Chronic portal hypertension is accompanied by a nitric oxide (NO) dependent vasodilation. Three isoforms of NO producing synthases (NOS) are characterized: neuronal NOS (nNOS), endothelial NOS (eNOS) and inducible NOS (iNOS). Sources of i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::337a6b816105f2c0061086733b2cc78c
https://doi.org/10.1034/j.1600-0676.2002.01653.x