Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Juemei Wang"'
Autor:
Michelle L. Fong, Connie B. Paik, Patricia M. Quiñones, Clayton B. Walker, Michael J. Serafino, Dorothy W. Pan, Eduardo Martinez, Juemei Wang, Grady W. Phillips, Brian E. Applegate, Michael Anne Gratton, John S. Oghalai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Endolymphatic hydrops, increased endolymphatic fluid within the cochlea, is the key pathologic finding in patients with Meniere’s disease, a disease of episodic vertigo, fluctuating hearing loss, tinnitus, and aural fullness. Endolymphatic
Externí odkaz:
https://doaj.org/article/15b3623acba34ca387d57161069ab796
Autor:
Ido Badash, Patricia M. Quiñones, Kevin J. Oghalai, Juemei Wang, Christopher G. Lui, Frank Macias-Escriva, Brian E. Applegate, John S. Oghalai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
After acoustic trauma, there can be loss of synaptic connections between inner hair cells and auditory neurons in the cochlea, which may lead to hearing abnormalities including speech-in-noise difficulties, tinnitus, and hyperacusis. We have previous
Externí odkaz:
https://doaj.org/article/bcda5e59e06c40df8d45b20139c06a59
Autor:
Joel Lavinsky, Marshall Ge, Amanda L. Crow, Calvin Pan, Juemei Wang, Pezhman Salehi, Anthony Myint, Eleazar Eskin, Hooman Allayee, Aldons J. Lusis, Rick A. Friedman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 10, Pp 3219-3228 (2016)
The discovery of environmentally specific genetic effects is crucial to the understanding of complex traits, such as susceptibility to noise-induced hearing loss (NIHL). We describe the first genome-wide association study (GWAS) for NIHL in a large a
Externí odkaz:
https://doaj.org/article/e292e33f3649402686a13eee2dfb0d52
Autor:
Pezhman Salehi, Marshall X Ge, Usha Gundimeda, Leah Michelle Baum, Homero Lael Cantu, Joel Lavinsky, Litao Tao, Anthony Myint, Charlene Cruz, Juemei Wang, Angeliki Maria Nikolakopoulou, Carolina Abdala, Matthew William Kelley, Takahiro Ohyama, Thomas Matthew Coate, Rick A Friedman
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007048 (2017)
Neuropilin-1 (Nrp1) encodes the transmembrane cellular receptor neuropilin-1, which is associated with cardiovascular and neuronal development and was within the peak SNP interval on chromosome 8 in our prior GWAS study on age-related hearing loss (A
Externí odkaz:
https://doaj.org/article/197dc0aae6f442fc9fbd254a8ce05297
Autor:
Joel Lavinsky, Amanda L Crow, Calvin Pan, Juemei Wang, Ksenia A Aaron, Maria K Ho, Qingzhong Li, Pehzman Salehide, Anthony Myint, Maya Monges-Hernadez, Eleazar Eskin, Hooman Allayee, Aldons J Lusis, Rick A Friedman
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005293 (2015)
Externí odkaz:
https://doaj.org/article/dd1c3b2e0dbb46a3a70a3faffb50ba27
Autor:
Joel Lavinsky, Amanda L Crow, Calvin Pan, Juemei Wang, Ksenia A Aaron, Maria K Ho, Qingzhong Li, Pehzman Salehide, Anthony Myint, Maya Monges-Hernadez, Eleazar Eskin, Hooman Allayee, Aldons J Lusis, Rick A Friedman
Publikováno v:
PLoS Genetics, Vol 11, Iss 4, p e1005094 (2015)
In the United States, roughly 10% of the population is exposed daily to hazardous levels of noise in the workplace. Twin studies estimate heritability for noise-induced hearing loss (NIHL) of approximately 36%, and strain specific variation in sensit
Externí odkaz:
https://doaj.org/article/94782504ad8043708b393a68af904bc6
Autor:
Danielle M. Gillard, Rick A. Friedman, Hooman Allayee, Ely Cheikh Boussaty, Aline Mendonça, Uri Manor, Juemei Wang, Pezhman Salehi, Joel Lavinsky
Publikováno v:
J Assoc Res Otolaryngol
This is the first genome-wide association study with the Hybrid Mouse Diversity Panel (HDMP) to define the genetic landscape of the variation in the suprathreshold wave 1 amplitude of the auditory brainstem response (ABR) both pre- and post-noise exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38f6a6d419c33eff473aad63652df82
https://doi.org/10.1007/s10162-020-00762-3
https://doi.org/10.1007/s10162-020-00762-3
Autor:
Juemei Wang, Pezhman Salehi, Aline Mendonça, Rick A. Friedman, Mariele Bressan, Joel Lavinsky, Ely Cheikh Boussaty, Vagner Antonio Rodrigues da Silva, Guilherme Kasperbauer
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 32(6)
ABR wave I amplitude represents the synapse of auditory nerve fibers with the inner hair cell and is highly correlated with synapse counts. Cochlear synaptopathy, the loss of synaptic connections between inner hair cells and auditory nerve fibers, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797dddad09dbd66f6c3bdf72fe7aaccb
https://pubmed.ncbi.nlm.nih.gov/34487237
https://pubmed.ncbi.nlm.nih.gov/34487237
Autor:
Joel Lavinsky, Ricardo Ferreira Bento, Juemei Wang, Guilherme Kasperbauer, Rick A. Friedman, Hooman Allayee, Aline Mendonça, Amanda L. Crow
Publikováno v:
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Audiol Neurootol
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Audiol Neurootol
Background: Although several candidate-gene association studies have been conducted to investigate noise-induced hearing loss (NIHL) in humans, most are underpowered, unreplicated, and account for only a fraction of the genetic risk. Mouse genome-wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a727d353067fc7ba7c978bafa7e0e418
Autor:
Jorge H. Martin, Juemei Wang, Daniel H. Cohn, David R. Eyre, Sitaram Vangala, Jorge Ortiz‐Sanchez, Karthika Balasubramanian, Deborah Krakow, Rick A. Friedman, Ivan Duran, MaryAnn Weis
Publikováno v:
American Journal of Medical Genetics Part A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fb16e3bb801e154f5df44f6eada9b7
https://doi.org/10.1002/ajmg.a.61208
https://doi.org/10.1002/ajmg.a.61208