Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy.

Autor: Russell AJ; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., DuVall M; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Barthel B; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Qian Y; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Peter AK; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Newell-Stamper BL; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Hunt K; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Lehman S; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Madden M; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Schlachter S; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Robertson B; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Van Deusen A; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Rodriguez HM; BridgeBio Inc., Palo Alto, California, USA., Vera C; Department of Molecular, Cellular, and Developmental Biology and BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Su Y; Molecular and Integrative Physiology and., Claflin DR; Department of Surgery, Section of Plastic Surgery, University of Michigan, Ann Arbor, Michigan, USA., Brooks SV; Molecular and Integrative Physiology and., Nghiem P; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA., Rutledge A; Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA., Juehne TI; Genome Technology Access Center, Department of Genetics, Washington University in Saint Louis School of Medicine, Saint Louis, Missouri, USA., Yu J; Genome Technology Access Center, Department of Genetics, Washington University in Saint Louis School of Medicine, Saint Louis, Missouri, USA., Barton ER; Department of Applied Physiology and Kinesiology and Myology Institute, University of Florida College of Health and Human Performance, Gainesville, Florida, USA., Luo YE; Department of Applied Physiology and Kinesiology and Myology Institute, University of Florida College of Health and Human Performance, Gainesville, Florida, USA., Patsalos A; Departments of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA., Nagy L; Departments of Medicine and Biological Chemistry, Johns Hopkins University School of Medicine, Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA., Sweeney HL; Department of Pharmacology and Therapeutics and Myology Institute, University of Florida College of Medicine, Gainesville, Florida, USA., Leinwand LA; Department of Molecular, Cellular, and Developmental Biology and BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA., Koch K; Edgewise Therapeutics, BioFrontiers Institute, University of Colorado, Boulder, Colorado, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2023 May 15; Vol. 133 (10). Date of Electronic Publication: 2023 May 15.

A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant.

Autor: Friend LD; Program in Immunology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Shah DD, Deppong C, Lin J, Bricker TL, Juehne TI, Rose CM, Green JM

Publikováno v: The Journal of experimental medicine [J Exp Med] 2006 Sep 04; Vol. 203 (9), pp. 2121-33. Date of Electronic Publication: 2006 Aug 14.