Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jue-Lon Shie"'
Autor:
Bruce A. Littlefield, Daniel Romo, Yuan Wang, Roch Boivin, Hong Du, Huiming Zhang, Yimin Jiang, Jue-Lon Shie, Zhihong Chen, Lana Parent, Natalie Twine, Sergei Agoulnik, Joanne Marsh, Nanding Zhao, Murray Towle, Junke Liu, Karen TenDyke, Lori Rudolph-Owen, Qunli Xu, Galina Kuznetsov
We report here that des-methyl, des-amino pateamine A (DMDA-PatA), a structurally simplified analogue of the marine natural product pateamine A, has potent antiproliferative activity against a wide variety of human cancer cell lines while showing rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d511a2972fe43cbe29e1cae8600cf49
https://doi.org/10.1158/1535-7163.c.6532254.v1
https://doi.org/10.1158/1535-7163.c.6532254.v1
Autor:
Bruce A. Littlefield, Daniel Romo, Yuan Wang, Roch Boivin, Hong Du, Huiming Zhang, Yimin Jiang, Jue-Lon Shie, Zhihong Chen, Lana Parent, Natalie Twine, Sergei Agoulnik, Joanne Marsh, Nanding Zhao, Murray Towle, Junke Liu, Karen TenDyke, Lori Rudolph-Owen, Qunli Xu, Galina Kuznetsov
Supplementary Data from Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a57b34d6639a87d9ea2a61f352ba72
https://doi.org/10.1158/1535-7163.22486140
https://doi.org/10.1158/1535-7163.22486140
Autor:
Shuzhen Guo, Angela F. Messmer-Blust, Jiaping Wu, Xiaoxiao Song, Melissa J. Philbrick, Jue-Lon Shie, Jamal S. Rana, Jian Li
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 3, Pp 3816-3833 (2014)
Tumor necrosis factor α (TNF-α) influences endothelial cell viability by altering the regulatory molecules involved in induction or suppression of apoptosis. However, the underlying mechanisms are still not completely understood. In this study, we
Externí odkaz:
https://doaj.org/article/fe2e9e25c7894bcba7c4f66cb905ae40
Autor:
Kenichi Nomoto, Kuan-Chun Huang, Donna Kolber-Simonds, Natalie C. Twine, George A. Moniz, Paul Chang, Jue-lon Shie, Jingzang Tao Miu, Karen Ackermann, Zhihong Chen, Sharon McGonigle, Jiayi Wu
Publikováno v:
Oncotarget
Impact Journals/National Center for Biotechnology Information (U.S.)
Impact Journals/National Center for Biotechnology Information (U.S.)
Inhibition of Poly(ADP-ribose) Polymerase1 (PARP1) impairs DNA damage repair, and early generation PARP1/2 inhibitors (olaparib, niraparib, etc.) have demonstrated clinical proof of concept for cancer treatment. Here, we describe the development of t
Autor:
Zoltan Dezso, Mary Woodall-Jappe, Jue-lon Shie, Galina Kuznetsov, Noel Taylor, Shannon McGrath, Sergei Agoulnik, Sharon McGonigle, Natalie C. Twine, Jiayi Wu, Shanqin Xu, Donna Kolber-Simonds, Kenichi Nomoto, Mark Matijevic
Publikováno v:
Cancer Research. 75:P5-06
Introduction: In a small neoadjuvant study in patients with triple negative breast cancer (TNBC) the combination of eribulin plus carboplatin was effective, with a pathologic complete response rate of 43% following 4 cycles of treatment. Significant
Autor:
Xiaoxiao Song, Angela F. Messmer-Blust, Melissa J. Philbrick, Jamal S. Rana, Jian Li, Jiaping Wu, Shuzhen Guo, Jue-Lon Shie
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 15, Iss 3, Pp 3816-3833 (2014)
International Journal of Molecular Sciences; Volume 15; Issue 3; Pages: 3816-3833
International Journal of Molecular Sciences, Vol 15, Iss 3, Pp 3816-3833 (2014)
International Journal of Molecular Sciences; Volume 15; Issue 3; Pages: 3816-3833
Tumor necrosis factor α (TNF-α) influences endothelial cell viability by altering the regulatory molecules involved in induction or suppression of apoptosis. However, the underlying mechanisms are still not completely understood. In this study, we
Publikováno v:
FEBS Letters. 477:67-72
Interferon-gamma (IFN-gamma) induces growth arrest and apoptosis of tumor cells but the mechanisms for these functions are unknown. Recently, gut-enriched krüppel-like factor (GKLF) was found to possess similar biological properties. Treatment of HT
Autor:
Isabel Lubenec, Yuhong Liu, Ping He, Jue-Lon Shie, Angela F. Messmer-Blust, Jian Li, Qinhui Song, Cuili Zhang, Frank W. Sellke
Objective: Related transcriptional enhancer factor 1 (RTEF-1) is a key transcriptional regulator in endothelial function. In this study, we investigated a possible role for RTEF-1 in the regulation of microvascular relaxation and the underlying mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fcbeb5927e11be00a74fbcd164ceaa6
https://europepmc.org/articles/PMC3369257/
https://europepmc.org/articles/PMC3369257/
Publikováno v:
Biochemical and biophysical research communications. 390(4)
Autor:
Karen TenDyke, Roch Boivin, Hong Du, Sergei Agoulnik, Daniel Romo, Yuan Wang, Zhihong Chen, Lana Parent, Huiming Zhang, Nanding Zhao, Bruce A. Littlefield, Jue-lon Shie, Yimin Jiang, Natalie C. Twine, Lori Rudolph-Owen, Murray J. Towle, Joanne Marsh, Qunli Xu, Junke Liu, Galina Kuznetsov
Publikováno v:
Molecular cancer therapeutics. 8(5)
We report here that des-methyl, des-amino pateamine A (DMDA-PatA), a structurally simplified analogue of the marine natural product pateamine A, has potent antiproliferative activity against a wide variety of human cancer cell lines while showing rel