Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Jue Yeon Lee"'
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2473
Multiple myeloma (MM) is the second most common hematological malignancy. It is a clonal B-cell disorder characterized by the proliferation of malignant plasma cells in the bone marrow, the presence of monoclonal serum immunoglobulin, and osteolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0699fc826860ec2677ac717dbac9f45
Autor:
Yoon Jeong Park, Gookjin Yoon, Jinsook Suh, Beom Soo Jo, Dong Woo Lee, Deogil Kim, Moonsil Choi, Eui Kyun Jeong, Hoo Cheol Lee, Jue-Yeon Lee, Chong Pyung Chung, Yoon Shin Park
The RAS-RAF-ERK1/2 pathway is a crucial target for anticancer drug development because of the high prevalence of ERK activation in human cancers. Mitogen-activated protein kinases (MAPKs) are pivotal intracellular cascade molecules critical in all eu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64d964586a9ceb21307c7064a216b035
https://doi.org/10.21203/rs.3.rs-2394020/v1
https://doi.org/10.21203/rs.3.rs-2394020/v1
Autor:
Kwang-Sook Park, Yoon Jeong Park, Beom Soo Jo, Dong Woo Lee, Chong Pyung Chung, Yoon Shin Park, Jue-Yeon Lee
Publikováno v:
Journal of Biomedical Materials Research Part A. 109:2001-2016
Various biomaterials have been used for bone and cartilage regeneration, and inflammation associated with biomaterial implantation is also increased. A 15-mer synthetic anti-inflammatory peptide (SAP15) was designed from human β-defensin 3 to penetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea69b1544bcc3695af2157fd3f195b2c
https://doi.org/10.1002/jbm.a.37192
https://doi.org/10.1002/jbm.a.37192
Autor:
Gookjin Yoon, Beom Soo Jo, Dong Woo Lee, Jinwook Yang, Min-Ho Park, Sanghui Seok, Jue Yeon Lee, Chong Pyoung Chung, Yoon Shin Park, Yoon Jeong Park
Publikováno v:
Molecular Cancer Research. 21:B039-B039
Activation of mutations in RAS has been found in high ratio in human cancers, inducing downstream critical effectors corresponding tumorigenesis. In recent years, RAS-RAF-ERK1/2 pathway is known as a crucial target for the anti-cancer drug developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8ec8de5d96e8bf47ee7a7ee20c7e2e5
https://doi.org/10.1158/1557-3125.ras23-b039
https://doi.org/10.1158/1557-3125.ras23-b039
Autor:
Gookjin Yoon, Beom Soo Jo, Dong Woo Lee, Jinwook Yang, Min-Ho Park, Sanghui Seok, Jue-Yeon Lee, Chong Pyung Chung, Yoon Jeong Park
Publikováno v:
Cancer Research. 83:569-569
Activation of mutations in RAS has been found in high ratio in human cancers, inducing downstream critical effectors corresponding tumorigenesis. The attempts in direct targeting to activated RAS, which is GTP bound, has been somewhat successful in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a44e89cb1856844f098760055e2c6930
https://doi.org/10.1158/1538-7445.am2023-569
https://doi.org/10.1158/1538-7445.am2023-569
Publikováno v:
Molecular & Cellular Toxicology. 15:245-254
Backgrounds: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. However, little is known about the molecular mechanisms of HCC development, progression, or effective therapeutic approaches. Recently, granulin-epithelin precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5316025e2fbef4f0a53d647665c11523
https://doi.org/10.1007/s13273-019-0028-6
https://doi.org/10.1007/s13273-019-0028-6
Autor:
Da Hyeon Choi, Jue Yeon Lee, Inho Jo, Jong Chul Park, Si Min Lee, Yoon Jeong Park, Yoon Shin Park, Kyeong Eun Lee, Ki Dong Park, Beom Soo Jo, Se Young Oh
Publikováno v:
Biomaterials. 278
Controlling the senescence of mesenchymal stem cells (MSCs) is essential for improving the efficacy of MSC-based therapies. Here, a model of MSC senescence was established by replicative subculture in tonsil-derived MSCs (TMSCs) using senescence-asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea5a69c8c154ff79a36b641e28b968e
https://pubmed.ncbi.nlm.nih.gov/34597900
https://pubmed.ncbi.nlm.nih.gov/34597900
Autor:
Da Hyeon Choi, Kyeong Eun Lee, Beom Soo Jo, Jue-Yeon Lee, Kwang-Sook Park, Yoon Jeong Park, Ju Kwang Choi, Yoon Shin Park, Dong Woo Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4251, p 4251 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 12
International Journal of Molecular Sciences
Volume 21
Issue 12
We report dual therapeutic effects of a synthetic heparin-binding peptide (HBP) corresponding to residues 15&ndash
24 of the heparin binding site in BMP4 in a collagen-induced rheumatic arthritis model (CIA) for the first time. The cell penetrat
24 of the heparin binding site in BMP4 in a collagen-induced rheumatic arthritis model (CIA) for the first time. The cell penetrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100650099f469a751a9383923281fd24
https://www.mdpi.com/1422-0067/21/12/4251
https://www.mdpi.com/1422-0067/21/12/4251
Publikováno v:
Annals of physical and rehabilitation medicine. 64(3)
Background Individuals with cerebral palsy (CP) experience bone loss due to impaired weight bearing. Despite serious complications, there is no standard medication. Objective To develop a new pharmacological agent, we performed a series of studies. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e80abee3a1cc9e1744a63ec933e8c6
https://pubmed.ncbi.nlm.nih.gov/33130040
https://pubmed.ncbi.nlm.nih.gov/33130040
Autor:
Deogil Kim, Dong Woo Lee, Eui Kyun Jeong, Hoo Cheol Lee, Yoon Shin Park, Jue Yeon Lee, Chong Pyung Chung, Yoon Jeong Park
Publikováno v:
Gastroenterology. 162:S64
Under Inflammatory bowel disease (IBD), impaired intestinal barrier from lumen is highly associated with ongoing IBD symptoms and it also contributes as a precursor for IBD. Current IBD therapeutics lack on mucosal regeneration, which the unmet needs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb968c904a93c89d1303609f0fbb516
https://doi.org/10.1053/j.gastro.2021.12.133
https://doi.org/10.1053/j.gastro.2021.12.133