Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Judyta Górka"'
Autor:
Paulina Marona, Judyta Górka, Oliwia Kwapisz, Jolanta Jura, Janusz Rys, Robert M. Hoffman, Katarzyna Miekus
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-17 (2022)
Abstract Tyrosine kinase inhibitors (TKIs) are the most commonly used targeted therapeutics in clear-cell renal cell carcinoma (ccRCC); however, drug resistance limits their utility and can lead to tumor “flare-up” and progression. In this study,
Externí odkaz:
https://doaj.org/article/b9b7dba8693f4e029e928c26b9639543
Autor:
Oliwia Kwapisz, Judyta Górka, Agata Korlatowicz, Jerzy Kotlinowski, Agnieszka Waligórska, Paulina Marona, Natalia Pydyn, Jurek W. Dobrucki, Jolanta Jura, Katarzyna Miekus
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1272 (2021)
Nonalcoholic fatty liver disease is defined as the accumulation of excessive fat in the liver in the absence of excessive alcohol consumption or any secondary cause. Although the disease generally remains asymptomatic, chronic liver inflammation lead
Externí odkaz:
https://doaj.org/article/705a06ddcb52407ba2a7786b755136d9
Autor:
Paulina Marona, Judyta Górka, Jerzy Kotlinowski, Marcin Majka, Jolanta Jura, Katarzyna Miekus
Publikováno v:
Cells, Vol 8, Iss 3, p 272 (2019)
C-Met tyrosine kinase receptor plays an important role under normal and pathological conditions. In tumor cells’ overexpression or incorrect activation of c-Met, this leads to stimulation of proliferation, survival and increase of motile activity.
Externí odkaz:
https://doaj.org/article/ee1bb0332efa4a1397865aa9080afc29
Autor:
Katarzyna Miekus, Jolanta Jura, Marcin Majka, Janusz Rys, Waclaw Wilk, Zofia Mazurek, Judyta Górka, Paulina Marona
Transient transfection with small interfering RNA (siRNA). Table 1. Sequences of primers Table 2. List of antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57702ba3b09fa4c92d3f3e88795017ee
https://doi.org/10.1158/0008-5472.22414575.v1
https://doi.org/10.1158/0008-5472.22414575.v1
Autor:
Katarzyna Miekus, Jolanta Jura, Marcin Majka, Janusz Rys, Waclaw Wilk, Zofia Mazurek, Judyta Górka, Paulina Marona
Supplementary Figure S1. Downregulation level of MCPIP1 using siRNA or shRNA. Supplementary Figure S2. Effect of MCPIP1 downregulation level on tutor growth. Supplementary Figure S3. MCPIP1 upregulation in Caki-1 and Caki-2 cell lines and tutor growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f968f6d86177cf1375d2a7a183f29e
https://doi.org/10.1158/0008-5472.22414578
https://doi.org/10.1158/0008-5472.22414578
Autor:
Katarzyna Miekus, Jolanta Jura, Marcin Majka, Janusz Rys, Waclaw Wilk, Zofia Mazurek, Judyta Górka, Paulina Marona
Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer and it forms highly vascularized tumors. The monocyte endoribonuclease MCPIP1 negatively regulates inflammation by degrading mRNA encoding proinflammatory cytokines, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec5065770b5e9b8f147a2f8d90c4c73
https://doi.org/10.1158/0008-5472.c.6509031.v1
https://doi.org/10.1158/0008-5472.c.6509031.v1
Autor:
Katarzyna Miekus, Jolanta Jura, Janusz Rys, Jurek Dobrucki, Oliwia Kwapisz, Paulina Marona, Ewelina Pospiech, Agnieszka Waligórska, Judyta Górka
Publikováno v:
Oncogene
Epithelial-mesenchymal transition (EMT) refers to the acquisition of mesenchymal properties in cells participating in tumor progression. One hallmark of EMT is the increased level of active β-catenin, which can trigger the transcription of Wnt-speci
Publikováno v:
European Journal of Pharmacology. 888:173591
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer. It is highly vascularized and largely resistant to traditional chemo- and radiotherapy. Decreases in tumour suppressors and low levels of the anti-inflammatory Monoc
Autor:
Janusz Rys, Judyta Górka, Waclaw Wilk, Paulina Marona, Jolanta Jura, Marcin Majka, Katarzyna Miekus, Zofia Mazurek
Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer and it forms highly vascularized tumors. The monocyte endoribonuclease MCPIP1 negatively regulates inflammation by degrading mRNA encoding proinflammatory cytokines, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c01abc0726b1911168f6de8cd9bb4fa
https://ruj.uj.edu.pl/xmlui/handle/item/44944
https://ruj.uj.edu.pl/xmlui/handle/item/44944
Publikováno v:
Cancer Research. 78:898-898
Introduction Clear cell renal cell carcinoma (ccRCC) treatment with small molecules that inhibit multiple receptor tyrosine kinases (RTKs),showed in approximately 38% of patients significant tumor control. However, despite the efficacy of treatment,