Výsledky vyhledávání - "Judy R. Richards"

TEMPORAL ASSOCIATION BETWEEN PULMONARY AND SYSTEMIC EFFECTS OF PARTICULATE MATTER IN HEALTHY AND CARDIOVASCULAR COMPROMISED RATS

Autor: Allen D. Ledbetter, Russ Hauser, Mette C. Schladweiler, David C. Christiani, Daniel L. Costa, Urmila P. Kodavanti, John K. McGee, Judy R. Richards

Publikováno v: Journal of Toxicology and Environmental Health, Part A. 65:1545-1569

Exposure to particulate matter (PM) has been associated with increased morbidity and mortality among individuals with cardiovascular disease. It is hypothesized that systemic alterations occur concurrent to pulmonary injury/inflammation, and contribu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9272bd9431c38be36700adbebab387
https://doi.org/10.1080/00984100290071667

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The Spontaneously Hypertensive Rat as a Model of Human Cardiovascular Disease: Evidence of Exacerbated Cardiopulmonary Injury and Oxidative Stress from Inhaled Emission Particulate Matter

Autor: Matthew J. Campen, Mette C. Schladweiler, Kay M. Crissman, Allen D. Ledbetter, Gary E. Hatch, Darrell W. Winsett, Judy R. Richards, William P. Watkinson, Urmila P. Kodavanti, Daniel L. Costa

Publikováno v: Toxicology and Applied Pharmacology. 164:250-263

Cardiovascular disease is considered a probable risk factor of particulate matter (PM)-related mortality and morbidity. It was hypothesized that rats with hereditary systemic hypertension and underlying cardiac disease would be more susceptible than

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa0b0128ed0c6f7963fd7dd682c0825
https://doi.org/10.1006/taap.2000.8899

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LUNG INJURY FROM INTRATRACHEAL AND INHALATION EXPOSURES TO RESIDUAL OIL FLY ASH IN A RAT MODEL OF MONOCROTALINE-INDUCED PULMONARY HYPERTENSION

Autor: Sarah Y. Gardner, Urmila P. Kodavanti, Mette C. Jackson, Matthew J. Campen, Allen D. Ledbetter, Daniel L. Costa, William P. Watkinson, Judy R. Richards

Publikováno v: Journal of Toxicology and Environmental Health, Part A. 57:543-563

A rat model of monocrotaline (MCT)-induced pulmonary injury/hypertension has been recently used in particulate matter (PM) health effects studies, however, results have been equivocal. Neither the mechanism by which mortality occurs in this model nor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9d45558b0b8c90f99b252959445e26
https://doi.org/10.1080/009841099157502

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Acute lung injury from intratracheal exposure to fugitive residual oil fly ash and its constituent metals in normo- and spontaneously hypertensive rats

Autor: Mette C. Schladweiler, Judy R. Richards, Daniel L. Costa, Urmila P. Kodavanti

Publikováno v: Inhalation toxicology. 13(1)

We have recently shown that the spontaneously hypertensive (SH) rats with underlying cardiovascular disease exhibited greater pulmonary vascular leakage and oxidative stress than healthy normotensive (Wistar Kyoto, WKY) rats after a 3-day inhalation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a116b299fe55e0ed1bf9d9182e02dc50
https://pubmed.ncbi.nlm.nih.gov/11153059

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