Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Judy R Kersten"'
Autor:
John F LaDisa, Serdar Bozdag, Jessica Olson, Ramani Ramchandran, Judy R Kersten, Thomas J Eddinger
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133356 (2015)
Coarctation of the aorta (CoA) is a constriction of the proximal descending thoracic aorta and is one of the most common congenital cardiovascular defects. Treatments for CoA improve life expectancy, but morbidity persists, particularly due to the de
Externí odkaz:
https://doaj.org/article/e3256136a17b40e0ad70195e948d3164
Autor:
Thorsten M Leucker, Zhi-Dong Ge, Jesse Procknow, Yanan Liu, Yang Shi, Martin Bienengraeber, David C Warltier, Judy R Kersten
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70088 (2013)
Endothelial-myocardial interactions may be critically important for ischemia/reperfusion injury. Tetrahydrobiopterin (BH4) is a required cofactor for nitric oxide (NO) production by endothelial NO synthase (eNOS). Hyperglycemia (HG) leads to signific
Externí odkaz:
https://doaj.org/article/2c12d953f25c46dfa5868db72b12b888
Autor:
Zhi-Dong Ge, David C. Warltier, Zhengyuan Xia, Yanan Liu, Shigang Qiao, Shelley L. Baumgardt, Judy R. Kersten, Juan Fang, Yang Shi, Jeannette Vasquez-Vivar, Zeljko J. Bosnjak
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
GTP cyclohydrolase 1 (GCH1) and its product tetrahydrobiopterin play crucial roles in cardiovascular health and disease, yet the exact regulation and role of GCH1 in adverse cardiac remodeling after myocardial infarction are still enigmatic. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866a5d036ee608a06a30b01696574259
http://hdl.handle.net/10722/249606
http://hdl.handle.net/10722/249606
Autor:
Julien Amour, Judy R. Kersten
Publikováno v:
Anaesthesia Critical Care & Pain Medicine. 37:S1-S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d9a2c4a5ad5641e4a587c0752e9977
https://doi.org/10.1016/j.accpm.2018.03.002
https://doi.org/10.1016/j.accpm.2018.03.002
Autor:
David C. Warltier, Dorothee Weihrauch, Adrian Coon, Zhi-Dong Ge, Judy R. Kersten, Ines Baotic, Filip Sedlic
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 305:H219-H227
Acute hyperglycemia (AHG) decreases the availability of nitric oxide (NO) and impairs anesthetic preconditioning (APC)-elicited protection against myocardial infarction. We investigated whether D-4F, an apolipoprotein A-1 mimetic, rescues the myocard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22be325cee475493625b04d6cf71d7a
https://doi.org/10.1152/ajpheart.00850.2012
https://doi.org/10.1152/ajpheart.00850.2012
Autor:
Shelley L. Baumgardt, David C. Warltier, Zhi-Dong Ge, Jianhai Du, Shigang Qiao, Yanan Liu, Juan Fang, Zeljko J. Bosnjak, Judy R. Kersten, Hsiang En Wu, Yang Shi, Mark Paterson
Publikováno v:
Scientific Reports
Diabetic cardiomyopathy increases the risk of heart failure and death. At present, there are no effective approaches to preventing its development in the clinic. Here we report that reduction of cardiac GTP cyclohydrolase 1 (GCH1) degradation by gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d577e4c1536a6281a625dc6468bfddbf
Autor:
Juan Fang, David X. Zhang, Judy R. Kersten, Zeljko J. Bosnjak, Zhi-Dong Ge, Thorsten M. Leucker, Mark Paterson, David C. Warltier, Shelley L. Baumgardt
Publikováno v:
Circulation. Heart failure. 9(1)
Background— Diabetic heart disease is associated with tetrahydrobiopterin oxidation and high arginase activity, leading to endothelial nitric oxide synthase dysfunction. Sepiapterin (SEP) is a tetrahydrobiopterin precursor, and l -citrulline ( l -C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd43215aacfbdc7cd05dc85d01a4a810
https://pubmed.ncbi.nlm.nih.gov/26763290
https://pubmed.ncbi.nlm.nih.gov/26763290
Autor:
Julien Amour, Judy R. Kersten
Publikováno v:
Anesthésie & Réanimation. 3:210-211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6870104833657410c750cd0d9f8d6007
https://doi.org/10.1016/j.anrea.2017.04.017
https://doi.org/10.1016/j.anrea.2017.04.017
Autor:
David C. Warltier, Ines Baotic, Maria Muravyeva, Martin Bienengraeber, Anna K. Brzezinska, Thorsten M. Leucker, Judy R. Kersten, Dorothee Weihrauch, Phillip F. Pratt
Publikováno v:
Journal of Molecular and Cellular Cardiology. 51:803-811
Endothelial cells (EC) serve a paracrine function to enhance signaling in cardiomyocytes (CM), and conversely, CM secrete factors that impact EC function. Understanding how EC interact with CM may be critically important in the context of ischemia-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9df252778e958f98d34cc58afdbfbe
https://doi.org/10.1016/j.yjmcc.2011.06.026
https://doi.org/10.1016/j.yjmcc.2011.06.026
Autor:
Jianhai Du, Zhi-Dong Ge, David C. Warltier, Anna K. Brzezinska, Thorsten M. Leucker, Nikolina Vladic, Phillip F. Pratt, Yang Shi, Judy R. Kersten
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 301:H2130-H2139
Cardioprotection by ischemic preconditioning (IPC) is impaired during hyperglycemia, but the mechanisms underlying this phenomenon are poorly understood. This study investigated the role of hyperglycemia to adversely modulate tetrahydrobiopterin (BH4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c572f242ec4eaf565c2420a9795193
https://doi.org/10.1152/ajpheart.01078.2010
https://doi.org/10.1152/ajpheart.01078.2010