Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Judy M Coulson"'
Autor:
Dorota Sabat‐Pośpiech, Kim Fabian‐Kolpanowicz, Helen Kalirai, Natalie Kipling, Sarah E Coupland, Judy M Coulson, Andrew B Fielding
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 4, Pp 383-394 (2022)
Abstract Uveal melanoma (UM) is the most common intraocular cancer in adults. Whilst treatment of primary UM (PUM) is often successful, around 50% of patients develop metastatic disease with poor outcomes, linked to chromosome 3 loss (monosomy 3, M3)
Externí odkaz:
https://doaj.org/article/e52134711fec4d00857b44a97422ee2d
Autor:
Sarah E. Barnett, Anne Herrmann, Liam Shaw, Elisabeth N. Gash, Harish Poptani, Joseph J. Sacco, Judy M. Coulson
Publikováno v:
Cancers, Vol 14, Iss 23, p 5836 (2022)
Malignant pleural mesothelioma (MPM) has limited treatment options and poor prognosis. Frequent inactivation of the tumour suppressors BAP1, NF2 and P16 may differentially sensitise tumours to treatments. We have established chick chorioallantoic mem
Externí odkaz:
https://doaj.org/article/16d633c83b9d456f91783e10d4ea7dbd
Autor:
Junxiu Sheng, Qingzhi Zhao, Jinyao Zhao, Wenjing Zhang, Yu Sun, Pan Qin, Yuesheng Lv, Lu Bai, Quan Yang, Lei Chen, Yangfan Qi, Ge Zhang, Lin Zhang, Chundong Gu, Xiaoqin Deng, Han Liu, Songshu Meng, Hong Gu, Quentin Liu, Judy M. Coulson, Xiaoling Li, Bing Sun, Yang Wang
Publikováno v:
EBioMedicine, Vol 38, Iss , Pp 113-126 (2018)
Background: Radioresistance is the major cause of cancer treatment failure. Additionally, splicing dysregulation plays critical roles in tumorigenesis. However, the involvement of alternative splicing in resistance of cancer cells to radiotherapy rem
Externí odkaz:
https://doaj.org/article/39f754e42fa4466ebce5a89733468611
Autor:
Sarah E. Barnett, Jenna Kenyani, Martina Tripari, Zohra Butt, Rudi Grosman, Francesca Querques, Liam Shaw, Luisa C. Silva, Zoe Goate, Stefan J. Marciniak, Doris M. Rassl, Richard Jackson, Lu-Yun Lian, Peter W. Szlosarek, Joseph J. Sacco, Judy M. Coulson
Publikováno v:
Molecular Cancer Research. 21:411-427
The nuclear deubiquitylase BRCA1-associated protein 1 (BAP1) is frequently inactivated in malignant pleural mesothelioma (MPM) and germline BAP1 mutation predisposes to cancers including MPM. To explore the influence on cell physiology and drug sensi
Publikováno v:
The Biochemical journal
Approximately 15% of all cancer patients harbor mutated KRAS. Direct inhibitors of KRAS have now been generated and are beginning to make progress through clinical trials. These include a suite of inhibitors targeting the KRASG12C mutation commonly f
Autor:
Judy M. Coulson, Joseph J. Sacco, Peter W. Szlosarek, Lu-Yun Lian, Richard Jackson, Doris M. Rassl, Stefan J. Marciniak, Zoe Goate, Luisa C. Silva, Liam Shaw, Francesca Querques, Rudi Grosman, Zohra Butt, Martina Tripari, Jenna Kenyani, Sarah E. Barnett
The nuclear deubiquitylase BRCA1-associated protein 1 (BAP1) is frequently inactivated in malignant pleural mesothelioma (MPM) and germline BAP1 mutation predisposes to cancers including MPM. To explore the influence on cell physiology and drug sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f2a26145563ea502d969aa75f1b8c3
https://doi.org/10.1158/1541-7786.c.6545790
https://doi.org/10.1158/1541-7786.c.6545790
Autor:
Judy M. Coulson, Joseph J. Sacco, Peter W. Szlosarek, Lu-Yun Lian, Richard Jackson, Doris M. Rassl, Stefan J. Marciniak, Zoe Goate, Luisa C. Silva, Liam Shaw, Francesca Querques, Rudi Grosman, Zohra Butt, Martina Tripari, Jenna Kenyani, Sarah E. Barnett
WGS MeT5A isogenics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf2154b4fb25b2e610c07de9a665f9b
https://doi.org/10.1158/1541-7786.22725152.v1
https://doi.org/10.1158/1541-7786.22725152.v1
Autor:
Judy M. Coulson, Joseph J. Sacco, Peter W. Szlosarek, Lu-Yun Lian, Richard Jackson, Doris M. Rassl, Stefan J. Marciniak, Zoe Goate, Luisa C. Silva, Liam Shaw, Francesca Querques, Rudi Grosman, Zohra Butt, Martina Tripari, Jenna Kenyani, Sarah E. Barnett
Supplementary Methods, References and List of Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf91e8fa62edb8842a191d49c5499d5
https://doi.org/10.1158/1541-7786.22528791
https://doi.org/10.1158/1541-7786.22528791
Autor:
Judy M. Coulson, Joseph J. Sacco, Peter W. Szlosarek, Lu-Yun Lian, Richard Jackson, Doris M. Rassl, Stefan J. Marciniak, Zoe Goate, Luisa C. Silva, Liam Shaw, Francesca Querques, Rudi Grosman, Zohra Butt, Martina Tripari, Jenna Kenyani, Sarah E. Barnett
Fig. S1. SNP6.0 analysis of parental MeT5A-BAP1+/+ cells.Fig. S2. Expression of catalytically active BAP1 in parental MeT5A.Fig. S3. Characterisation of BAP1 expression in gene-edited MeT5A.Fig. S4. Whole genome sequencing of gene-edited MeT5A.Fig. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f6fcf22fd1f133b9edf46c65ca1fbe
https://doi.org/10.1158/1541-7786.22528794
https://doi.org/10.1158/1541-7786.22528794
Autor:
Ian A. Prior, Patrick A. Eyers, Paul D. Smith, Joseph R. Slupsky, Sarah J. Ross, David J. MacEwan, Judy M. Coulson, Fiona E. Hood, Dean E. Hammond, Adam Linley, Leah J. Wilson
The human protein kinome comprises 535 proteins that, with the exception of approximately 50 pseudokinases, control intracellular signaling networks by catalyzing the phosphorylation of multiple protein substrates. While a major research focus of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd2ef03c897f56937b46b2d011e2a10
https://doi.org/10.1158/0008-5472.c.6509586.v1
https://doi.org/10.1158/0008-5472.c.6509586.v1