Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Judy K, VanSlyke"'
Autor:
Linda S. Musil, Michael Heinrich, Amber E Bannon, Lillian R. Klug, Jonathan A. Fletcher, Ajia Town, William H. Fleming, Nathalie Javidi-Sharifi, Judy K. VanSlyke, Jeffrey W. Tyner
Publikováno v:
Oncogene
Certain cancers, including gastrointestinal stromal tumor (GIST) and subsets of melanoma, are caused by somatic KIT mutations that result in KIT receptor tyrosine kinase constitutive activity, which drives proliferation. The treatment of KIT-mutant G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e95518a9e8a0b2d4a29331edd8cb8c
https://doi.org/10.1038/s41388-018-0508-5
https://doi.org/10.1038/s41388-018-0508-5
Publikováno v:
Journal of cell science. 131(22)
Lens epithelial cells are bound to the lens extracellular matrix capsule, of which laminin is a major component. After cataract surgery, surviving lens epithelial cells are exposed to increased levels of fibronectin, and so we addressed whether fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::989fe6438ae7aa6a1ee251dc1c811577
https://pubmed.ncbi.nlm.nih.gov/30404825
https://pubmed.ncbi.nlm.nih.gov/30404825
Publikováno v:
Journal of Cell Science.
Lens epithelial cells are bound to the lens extracellular matrix capsule, of which laminin is a major component. After cataract surgery, surviving lens epithelial cells are exposed to increased levels of fibronectin, and so we addressed whether fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77eec25f397acf31dba333659e920d86
https://doi.org/10.1242/jcs.217240
https://doi.org/10.1242/jcs.217240
Publikováno v:
Molecular Biology of the Cell
Using cultured lens epithelial cells, we discovered a new type of cross-talk between the FGF and TGF-β pathways, as well as a novel role for TGF-β and p38 kinase in the regulation of gap junctional intercellular communication. Our findings provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e6ddb3b74afe39685df229ece65b9c
https://doi.org/10.1091/mbc.e10-01-0055
https://doi.org/10.1091/mbc.e10-01-0055
Publikováno v:
Molecular Biology of the Cell
For all previously well-characterized oligomeric integral membrane proteins, folding, multisubunit assembly, and recognition of conformationally immature molecules for degradation occurs at their organelle of synthesis. This cannot, however, be the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0eeccc84e5dc186619eea26ce09a5e9
https://doi.org/10.1091/mbc.e09-01-0062
https://doi.org/10.1091/mbc.e09-01-0062
Autor:
Linda S. Musil, Judy K. VanSlyke
Publikováno v:
Molecular Biology of the Cell. 16:5247-5257
The protein constituents of gap junctions, connexins, have a rapid basal rate of degradation even after transport to the cell surface. We have used cell surface biotinylation to label gap junction-unassembled plasma membrane pools of connexin43 (Cx43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0c71658e8c4b9a60ef6535f5036547
https://doi.org/10.1091/mbc.e05-05-0415
https://doi.org/10.1091/mbc.e05-05-0415
Autor:
Linda S. Musil, Judy K. VanSlyke
Publikováno v:
Cell Communication & Adhesion. 10:329-333
Little is known about the mechanism and regulation of connexin turnover from the plasma membrane. We have used a combination of cell surface biotinylation, immunofluorescence microscopy, and scrape-load dye transfer assays to investigate the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0e5bb61f42cc4f97c169a84bbf3d98
https://doi.org/10.1080/cac.10.4-6.329.333
https://doi.org/10.1080/cac.10.4-6.329.333
Autor:
Linda S. Musil, Judy K. VanSlyke
Publikováno v:
Methods. 20:156-164
Central to understanding the establishment and regulation of gap junction-mediated intercellular communication is a detailed knowledge of how these complex structures are assembled. In this article, we describe methods to modulate and/or monitor the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bdf7ea22fccff12cf4d026ae921869
https://doi.org/10.1006/meth.1999.0933
https://doi.org/10.1006/meth.1999.0933
Publikováno v:
The EMBO Journal. 16:1508-1518
Activation of furin requires autoproteolytic cleavage of its 83‐amino acid propeptide at the consensus furin site, Arg‐Thr‐Lys‐Arg107 ↓ . This RER‐localized cleavage is necessary, but not sufficient, for enzyme activation. Rather, full ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7c9b6624609970e0cb7b98907336d8
https://doi.org/10.1093/emboj/16.7.1508
https://doi.org/10.1093/emboj/16.7.1508
Publikováno v:
Virus Genes. 7:311-324
Vaccinia virus (VV) virion morphogenesis is a complex sequence of events that occurs late in viral infection that is essential for the production of mature progeny. Electron microscopy studies have identified multiple morphogenic forms of virus parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5280da6ed250353f891ff06007087547
https://doi.org/10.1007/bf01703388
https://doi.org/10.1007/bf01703388