Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Judy E. Richards"'
Autor:
Judy E. Richards, Caroline Ghio, Mette C. Schladweiler, Andrew J. Ghio, Christopher J. Gordon, Samantha J. Snow, Urmila P. Kodavanti, Joleen M. Soukup
Publikováno v:
Biometals
To determine the effects of repeated physical activity on iron and zinc homeostases in a living system, we quantified blood and tissue levels of these two metals in sedentary and physically active Long-Evans rats. At post-natal day (PND) 22, female r
Autor:
Samantha J. Snow, Jonathan D. Krug, John M. Turlington, Judy E. Richards, Mette C. Schladweiler, Allen D. Ledbetter, Todd Krantz, Charly King, M. Ian Gilmour, Stephen H. Gavett, Urmila P. Kodavanti, Aimen K. Farraj, Mehdi S. Hazari
Publikováno v:
Atmospheric Environment. 295:119525
Autor:
Janice A. Dye, Marie M. Hargrove, Mette C. Schladweiler, Colette N. Miller, Urmila P. Kodavanti, Judy E. Richards, Andres R. Henriquez, Allen D. Ledbetter, Samantha J. Snow
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Agonists of β2 adrenergic receptors (β2AR) and glucocorticoid receptors (GR) are prescribed to treat pulmonary diseases. Since ozone effects are mediated through the activation of AR and GR, we hypothesized that the treatment of rats with relevant
Autor:
Samantha J. Snow, Kymberly M. Gowdy, Myles X Hodge, Andres R. Henriquez, Haiyan Tong, Brian N. Chorley, Judy E. Richards, Mette C. Schladweiler, Virgina Bass, Allen D. Ledbetter, Wan-Yun Cheng, Urmila P. Kodavanti, Gail M. Nelson, Gleta Carswell
Publikováno v:
Toxicological Sciences. 163:57-69
Fish, olive, and coconut oil dietary supplementation have several cardioprotective benefits, but it is not established if they protect against air pollution-induced adverse effects. We hypothesized that these dietary supplements would attenuate ozone
Adrenergic and glucocorticoid receptor antagonists reduce ozone-induced lung injury and inflammation
Autor:
Kevin Mauge-Lewis, Andres R. Henriquez, Mette C. Schladweiler, Colette N. Miller, Urmila P. Kodavanti, Allen D. Ledbetter, Marie A. McGee, Judy E. Richards, Janice A. Dye, Samantha J. Snow
Publikováno v:
Toxicology and Applied Pharmacology. 339:161-171
Recent studies showed that the circulating stress hormones, epinephrine and corticosterone/cortisol, are involved in mediating ozone-induced pulmonary effects through the activation of the sympathetic-adrenal-medullary (SAM) and hypothalamus-pituitar
Autor:
Judy E. Richards, Samantha J. Snow, Mette C. Schladweiler, Urmila P. Kodavanti, Marie A. McGee, Allen D. Ledbetter, Andres R. Henriquez
Publikováno v:
Toxicological Sciences. 158:454-464
Previous studies have demonstrated that exposure to the pulmonary irritant ozone causes myriad systemic metabolic and pulmonary effects attributed to sympathetic and hypothalamus-pituitary-adrenal (HPA) axis activation, which are exacerbated in metab
Diets enriched with coconut, fish, or olive oil modify peripheral metabolic effects of ozone in rats
Autor:
Andres R. Henriquez, Haiyan Tong, Beena Vallanat, Michelle M. Angrish, Anna Fisher, Judy E. Richards, Wan-Yun Cheng, Charles E. Wood, Mette C. Schladweiler, Urmila P. Kodavanti, Travis Goeden, Jenifer I. Fenton, Samantha J. Snow
Publikováno v:
Toxicol Appl Pharmacol
Dietary factors may modulate metabolic effects of air pollutant exposures. We hypothesized that diets enriched with coconut oil (CO), fish oil (FO), or olive oil (OO) would alter ozone-induced metabolic responses. Male Wistar-Kyoto rats (1-month-old)
Autor:
Judy E. Richards, Allen D. Ledbetter, Mette C. Schladweiler, Urmila P. Kodavanti, Samantha J. Snow, Andres R. Henriquez, Desinia B. Miller, Debora L. Andrews
Publikováno v:
Toxicology and Applied Pharmacology. 306:47-57
Acute ozone exposure induces a classical stress response with elevated circulating stress hormones along with changes in glucose, protein and lipid metabolism in rats, with similar alterations in ozone-exposed humans. These stress-mediated changes ov
Autor:
Janice A. Dye, Mette C. Schladweiler, Colette N. Miller, Wanda C. Williams, Judy E. Richards, Andres R. Henriquez, Urmila P. Kodavanti, Marie M. Hargrove, Samantha J. Snow, Allen D. Ledbetter
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 166(2)
We have shown that acute ozone inhalation activates sympathetic-adrenal-medullary and hypothalamus-pituitary-adrenal stress axes, and adrenalectomy (AD) inhibits ozone-induced lung injury and inflammation. Therefore, we hypothesized that stress hormo
Autor:
William O. Ward, Andrew J. Ghio, Wayne E. Cascio, Jan C. Jones, Judy E. Richards, Virginia L. Bass, Allen D. Ledbetter, Mette C. Schladweiler, Samantha J. Snow, Urmila P. Kodavanti, Beena Vallanat, Edward D. Karoly, Debora L. Andrews, Desinia B. Miller
Publikováno v:
Toxicology and Applied Pharmacology. 286:65-79
Air pollution has been linked to increased incidence of diabetes. Recently, we showed that ozone (O3) induces glucose intolerance, and increases serum leptin and epinephrine in Brown Norway rats. In this study, we hypothesized that O3 exposure will c