Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Judy D. Easterbrook"'
Autor:
Jeffery K. Taubenberger, Ishrat Sultana, Judy D. Easterbrook, Mohsen Rajabi, Kemin Xu, Xiufan Liu, Hongjun Chen, Daniel R. Perez, Laura Couzens, Xiu-Feng Wan, Lei Zhong, Katie H. Rivers, Maryna C. Eichelberger, Hongquan Wan, Jin Gao, Kevin Yang, Jianqiang Ye
Publikováno v:
Journal of Virology. 87:9290-9300
Influenza A viruses, including H1N1 and H5N1 subtypes, pose a serious threat to public health. Neuraminidase (NA)-related immunity contributes to protection against influenza virus infection. Antibodies to the N1 subtype provide protection against ho
Autor:
James Edwin Hall, Mariappan Anbazhagan, John H. Ansede, David W. Boykin, Reto Brun, Judy D. Easterbrook
Publikováno v:
Journal of Medicinal Chemistry. 47:4335-4338
Five O-alkoxyamidine analogues of the prodrug 2,5-bis[4-methoxyamidinophenyl]furan were synthesized and evaluated against Trypanosoma brucei rhodesiense in the STIB900 mouse model by oral administration. The observed in vivo activity of these prodrug
Autor:
Farial A. Tanious, David W. Boykin, W. David Wilson, Judy D. Easterbrook, Reto Brun, Mohamed A. Ismail
Publikováno v:
Journal of Medicinal Chemistry. 46:4761-4769
6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine (8a) was synthesized from 6-[5-(4-cyanophenyl)furan-2-yl]nicotinonitrile (4a), through the bis-O-acetoxyamidoxime followed by hydrogenation. Compound 4a was prepared via selective bromination of 6-(fura