Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Judy Cam"'
Autor:
Eliezer Masliah, Abba J. Kastin, Thomas Lake, Alan D. Snow, Paula Y. Choi, Lesley Larsen, Judy Cam, Steven G. Wood, Joel Cummings, Qubai Hu, Edward Rockenstein, Weihong Pan, Stephen Lorimer, Beth P. Nguyen, Daniel A. Kirschner, Rudolph E. Tanzi, Gerardo M. Castillo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-28 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-28 (2019)
Brain aging and Alzheimer’s disease both demonstrate the accumulation of beta-amyloid protein containing “plaques” and tau protein containing “tangles” that contribute to accelerated memory loss and cognitive decline. In the present investi
Autor:
Judy Cam, John R. Cirrito, Kelly R. Bales, Steven M. Paul, Min Zhuo, David F. Wozniak, Celina V. Zerbinatti, David M. Holtzman, Hiroshi Osaka, Guojun Bu
Publikováno v:
Proceedings of the National Academy of Sciences. 101:1075-1080
Amyloid-β peptide (Aβ) is central to the pathogenesis of Alzheimer's disease, and the low-density lipoprotein receptor-related protein (LRP) has been shown to alter Aβ metabolism in vitro . Here, we show that overexpression of a functional LRP min
Autor:
Judy Cam, Alan D. Snow, Joel Cummings, Thomas Lake, Qubai Hu, Kelsey Hanson, Luke A. Esposito
Publikováno v:
Alzheimer's & Dementia. 10
Publikováno v:
Molecular Neurobiology. 23:53-68
The low-density lipoprotein receptor (LDLR) family is composed of a class of single transmembrane glycoproteins, generally recognized as cell surface endocytic receptors, which bind and internalize extracellular ligands for degradation by lysosomes.
Autor:
Kelsey Hanson, Qubai Hu, Alan D. Snow, Marisa-Claire Yadon, Joel Cummings, Judy Cam, Thomas Lake, Luke A. Esposito
Publikováno v:
Alzheimer's & Dementia. 8
Autor:
Alan D. Snow, Luke A. Esposito, Marisa-Claire Yadon, Judy Cam, Joel Cummings, Qubai Hu, Thomas Lake
Publikováno v:
Alzheimer's & Dementia. 7
Autor:
Thomas Lake, Alan D. Snow, Luke A. Esposito, Joel Cummings, Judy Cam, Steve Runnels, Elizabeth Smith, Michael Hudson, Qubai Hu
Publikováno v:
Alzheimer's & Dementia. 5
Autor:
Jocelyn R. Aker, F. Michael Hudson, Luke A. Esposito, Steve Runnels, Joel Cummings, Judy Cam, Qubai Hu, Thomas P. Lake, Alan D. Snow
Publikováno v:
Alzheimer's & Dementia. 4
Autor:
Jiyeon Lee, Maria Paz Marzolo, María Inés Barría, Nibaldo C. Inestrosa, Guojun Bu, Claudia A. Escudero, Claudia Araya, Rodrigo A. Fuentealba, Francisca C. Bronfman, Judy Cam
Publikováno v:
Molecular Neurodegeneration, Vol 2, Iss 1, p 14 (2007)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background The generation of the amyloid-β peptide (Aβ) through the proteolytic processing of the amyloid precursor protein (APP) is a central event in the pathogenesis of Alzheimer's disease (AD). Recent studies highlight APP endocytosis and local
Publikováno v:
Annals of the New York Academy of Sciences. 1086
Amyloid-beta peptide (Abeta) production and accumulation in the brain is a central event in the pathogenesis of Alzheimer's disease (AD). Recent studies have shown that apolipoprotein E (apoE) receptors, members of the low-density lipoprotein recepto