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Publikováno v:
Clinical Endocrinology. 6:19-28
SUMMARY Growth hormone and prolactin are secreted episodically in man and experimental animals. To investigate physiologic mechanisms of GH and PRL secretion, a series of experiments were performed in individual, unanaesthetized male and female rats.
Publikováno v:
Endocrinology. 96(4)
Morphine in intravenous doses ranging from 10 μg/kg t o 8 mg/kg was shown to be effective in stimulating GH release in the unanesthetized rat. The response to thelog of the dose was linear over a range of 10 to 1000 μg/kg. Somatostatin (GH-release
Publikováno v:
Endocrinology. 102(1)
The effects on GH and PRL secretion of several pharmacological agents known to modify central neurotransmitter action were determined in unanesthetized male rats. Phenoxybenzamine, an alpha-adrenergic blocker (5 mg/kg iv), abolished episodic GH secre